Navigation Links
Herpes Suppression May Not Prevent HIV Infection
Date:6/19/2008

Study with antiviral aciclovir shows no added benefit

THURSDAY, June 19 (HealthDay News) -- The herpes drug aciclovir (Zovirax) doesn't reduce the risk of HIV-1 infection in people who have sex with men infected with genital herpes, a U.S. study finds.

Previous research has shown that herpes simplex virus type-2 (HSV-2) infection -- the most common cause of genital herpes -- increases the risk for HIV-1 infection by two- to threefold.

In this new, randomized, placebo-controlled phase III study, Dr. Connie Celum, of the University of Washington in Seattle, and colleagues examined whether aciclovir, an antiviral drug commonly used to help suppress genital herpes, would reduce the risk of HIV-1 infection.

The final analysis included almost 1,400 HIV-negative but HSV-2 positive women in Africa and more than 1,800 American and Peruvian men who have sex with men. Of those participants, almost 1,600 received 400 milligrams of aciclovir and a similar number received a placebo, for 12 to 18 months.

The incidence of HIV-1 infection was 3.9 per 100 person years in the aciclovir group and 3.3 per 100 in the placebo group -- not a significant difference, the researchers reported in the June 21 edition of The Lancet. In the aciclovir group, incidence of genital ulcers was reduced by 47 percent, and incidence of genital ulcers caused by HSV-2 was reduced by 63 percent.

"Our results show that suppressive therapy with standard doses of aciclovir is not effective in reduction of HIV-1 acquisition in HSV-2 seropositive women and MSM (men who have sex with men). Novel strategies are needed to interrupt interactions between HSV-2 and HIV-1," the researchers concluded.

Further research is needed to determine why aciclovir doesn't reduce the risk of HIV infection, they added.

These findings and others raise doubts about whether control of sexually-transmitted infections should be promoted sp
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Study Ties Herpes Virus to Emerging Form of Diabetes
2. Study finds genetic link to human herpes susceptibility
3. Study shows suppressing herpes virus may reduce infectiousness of HIV
4. Vicriviroc Demonstrates Potent and Sustained Viral Suppression Through 48 Weeks of Therapy in Treatment-Experienced HIV-Infected Patients
5. Ninety-one Percent of BARACLUDE(R) (entecavir) Treated Patients in a Four-Year Cohort Demonstrated Virologic Suppression to Undetectable Levels
6. Safe to Stop the Flow?: Differing Attitudes Found Between Women and Doctors Concerning Menstrual Suppression
7. Differing attitudes found between women and doctors concerning menstrual suppression
8. Pill box organizers increase HIV patients adherence and improve viral suppression
9. National Campaign to Prevent Teen and Unplanned Pregnancy Statement on Jamie Lynn Spears
10. U.S. Preventive Medicine Views Bernankes Comments as Strong Support for Prevention and Wellness Programs
11. Data Published in Plastic and Reconstructive Surgery Show Cohera Medicals Surgical Adhesive, TissuGlu(R), Prevents Seroma Formation in Animal Abdominoplasty Model
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Herpes Suppression May Not Prevent HIV Infection
(Date:3/5/2015)... FL (PRWEB) March 05, 2015 Nutrition ... nutrition products, is pleased to offer reformulated Millennium 500 ... website, Millennium 500 is a German grade creatine supplement ... hydration, promote muscle recovery, and aid with overall strength ... compound that acts as a reserve energy source in ...
(Date:3/5/2015)... (PRWEB) March 05, 2015 Think it’s tough ... even tougher to get them to brush their teeth. That’s ... parents released today by Delta Dental(1) in conjunction with National ... (45 percent) say getting kids to brush their teeth is ... to do. That’s slightly higher than getting children to eat ...
(Date:3/5/2015)... IL (PRWEB) March 05, 2015 The ... announce their sponsorship of the upcoming Crain’s Chicago Business ... , The Physicians' Breakfast will take place from 7:30 ... East Pearson Street, Chicago, IL 60611. The morning’s events ... Chicago’s top healthcare professionals. , The panel discussion ...
(Date:3/5/2015)... March 5, 2015 – As National ... (March 8-14, 2015), children’s hospitals around the country are ... hospital stays as safe as possible for their children. ... Solutions for Patient Safety (SPS) and the Children’s Hospital ... follow when visiting the hospital with their child. ...
(Date:3/5/2015)... 2015 Daily Greens™, an organic ... smoothie line, Half Pint that will debut nationwide, ... Greens’™ current offerings, Half Pint is crafted with ... and other ingredients that are sourced locally whenever ... To preserve nutrients and extend shelf life, the ...
Breaking Medicine News(10 mins):Health News:Nutrition Leaders Offers Reformulated Millennium 500 German Grade Creatine 2Health News:Delta Dental Survey Says Parents Have Harder Time Getting Kids to Brush than to Eat Vegetables 2Health News:Delta Dental Survey Says Parents Have Harder Time Getting Kids to Brush than to Eat Vegetables 3Health News:Cook County Law Firm to Sponsor Physicians Breakfast 2Health News:Children’s Hospitals Offer Safety Tips for Patient Families During National Patient Safety Awareness Week 2Health News:Children’s Hospitals Offer Safety Tips for Patient Families During National Patient Safety Awareness Week 3Health News:Children’s Hospitals Offer Safety Tips for Patient Families During National Patient Safety Awareness Week 4Health News:Daily Greens™ Debuts Organic Cold-Pressed Smoothie Line for Kids Exclusively in Whole Foods Markets 2Health News:Daily Greens™ Debuts Organic Cold-Pressed Smoothie Line for Kids Exclusively in Whole Foods Markets 3
... Although gynecologic cancers account for only 10 percent ... account for 20 percent of all female cancer survivors. ... increasingly important to detect recurrence. The Clinical Practice Committee ... a Clinical Document outlining their expert recommendations for cancer ...
... which provide prior authorization for imaging services using proprietary ... physicians and have the potential to either increase or ... June issue of the Journal of the American ... RBMs are widely used by private payers to manage ...
... HealthDay Reporter , TUESDAY, May 31 (HealthDay News) -- ... are as prone to fractures as people with osteoporosis, a ... recommend a bone density test to look for signs of ... use in older people with type 2 diabetes has been ...
... Mich. Children who are bullies or have conduct ... during the day according to University of Michigan Medical ... in the Ypsilanti, Michigan public schools who had exhibited ... that there was a two-fold higher risk for symptoms ...
... News) -- Surgeon fatigue has been blamed for adverse outcomes ... that time of day has no effect on the survival ... aren,t suggesting that fatigue is good," said the study,s lead ... at the Johns Hopkins University School of Medicine, in a ...
... article in The New Republic, Daniel Callahan and Sherwin ... requiring new ways of thinking about living, aging, and dying. ... the U.S. will have to reprioritize to emphasize public health ... the elderly. An interesting twist on their argument, which ...
Cached Medicine News:Health News:SGO sets new standards to monitor recurrence of gynecologic cancer more effectively 2Health News:Radiology benefit managers adversely affect referring physicians, study suggests 2Health News:In Diabetics, Good Scores on Bone Tests May Not Rule Out Risk 2Health News:In Diabetics, Good Scores on Bone Tests May Not Rule Out Risk 3Health News:Kids who bully, are aggressive are twice as likely to have sleep problems 2Health News:Transplant Surgery No Riskier at Night: Study 2Health News:What can we do about death? Reinventing the American medical system 2
(Date:3/5/2015)... , March 5, 2015 LUNGevity ... the Food and Drug Administration,s (FDA) approval of ... Opdivo and other immunotherapy treatments add another critical ... harnessing the power of a patient,s own immune ... has been approved specifically for patients with squamous ...
(Date:3/5/2015)... and Markets ( http://www.researchandmarkets.com/research/4q7gwz/india_pharma ) has announced ... Accelerating growth to the next level - Moving up ... offering. Domestic sales improved in 2014, ... the market,s reaction to the new drug pricing policy. ... healthy, as the momentum continues and improving economic growth ...
(Date:3/5/2015)... , Mar. 05, 2015 Research and Markets ... the "Japan Pharma Outlook 2015: Year to Watch ... Initiatives" report to their offering. ... from April -2014 (Annexure 1) is a ... - whether generic or innovator. The most of the ...
Breaking Medicine Technology:LUNGevity Foundation Applauds FDA Approval of Immunotherapy Drug Opdivo 2LUNGevity Foundation Applauds FDA Approval of Immunotherapy Drug Opdivo 3India Pharma Outlook 2015: Accelerating growth to the next level - Moving up the value chain beyond Generics 2India Pharma Outlook 2015: Accelerating growth to the next level - Moving up the value chain beyond Generics 3Japan Pharma Outlook 2015: Year to Watch out for Authorized Generics (AGs), Biosimilars and Overseas Strategic Initiatives 2Japan Pharma Outlook 2015: Year to Watch out for Authorized Generics (AGs), Biosimilars and Overseas Strategic Initiatives 3
... user-friendly instrument is the ... analyzer for the medium ... a well established nephelometric ... for a wide range ...
... Medtronic Diagnostic Workstation is the ... gastrointestinal function testing needs. , ... allowing you to expand with ... consistency and reliability of working ...
The Medtronic G|3 Urodynamic System is designed to make,your job easier, with the intuitive Sensic Navigation,Software and increased hardware functionality and options....
... 2000 Capillary Electrophoresis System uses revolutionary ... electrophoresis (SPE), urine protein electrophoresis and ... accurate analysis. The system is truly ... and no staining to process patient ...
Medicine Products: