Navigation Links
Here comes the sun
Date:1/17/2014

>Simulation of vitamin D deficiency in mice

The scientists worked with genetically modified mice to explore the details of the mechanism. The vitamin D receptors in the animals were changed so that no vitamin D signalling was possible. Vitamin D also regulates the body's calcium and phosphate balance, so the rodents were given a special diet to ensure that they had enough calcium and phosphorus. The lack of vitamin D was therefore the only deficiency that could have affected the physiology of the animals.

After about a year without vitamin D signalling, the mice had increased blood pressure amplitude. The researchers conducted a series of studies on various tissues from the animals. To understand what lies behind the increased blood pressure amplitude, they focused particularly on the aorta and found decreased expression of eNOS, increased deposition of collagen and fewer elastic fibres. Over time, the blood vessels had become more rigid and less able to adapt flexibly to the volume of blood streaming through them. The consequence was increased blood pressure amplitude and changes in cardiac structure and function. In future studies, the researchers want to examine whether vitamin D affects different cell types in blood vessels in different ways.

Refuelling light for the heart and the circulation

In Europe, it has often been considered to enrich certain foods with vitamin D, as is customary in the United States, for example. However, an external source of vitamin D also carries risks since any excess vitamin D cannot be excreted by the body. When used at very high doses it can lead to calcium deposits in blood vessels, kidneys, lungs and the heart. However, a lack of vitamin D can also have dramatic consequences. Institute board Professor Reinhold Erben states: "It is not that vitamin D deficiency will lead immediately to an increase in blood pressure amplitude or blood pressure, but over the long term it can lead to ca
'/>"/>

Contact: Reinhold Erben
reinhold.erben@vetmeduni.ac.at
43-125-077-4550
University of Veterinary Medicine -- Vienna
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. A Delray Beach Fav, Bella Reina Spa, Becomes a Vocus Video Feature
2. Family Voices Awarded Project to Fight Childhood Obesity by the Patient-Centered Outcomes Research Institute
3. OhioHealth Welcomes New Physical Medicine and Rehabilitation Specialist
4. Global Food Exchange Welcomes D. Scott Robinson and Duane Reed
5. Global Food Exchange™ Welcomes Joe Ignat
6. How to Make 2014 the Year Your Agency Becomes More Efficient, Improves Communication and Goes Mobile with Online Services from Aladtec
7. Passages Malibu Welcomes 2014 With Tips for Starting Fresh
8. Crisis and Trauma Recovery Self-help Book by Renowned Therapist Tracie O’Keefe Becomes Number 1 Amazon Bestseller
9. Home Care Assistance of Cleveland Welcomes New Client Care Manager
10. Hiscall, Inc. Becomes a Member of the Mid-South Sign Association, an Affiliate of the International Sign Association
11. The Florida State Hospital Association Becomes Supporting Organization of the Healthier Hospitals Initiative
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Here comes the sun
(Date:11/27/2014)... In addition to a new dessert recipe ... this holiday season and become educated about the warning ... over the holidays may raise questions about the physical ... in cognitive ability can occur with age, serious memory ... the difference between normal aging and more serious problems ...
(Date:11/26/2014)... Angeles, CA (PRWEB) November 26, 2014 ... to treat themselves this holiday season! With Parsa Mohebi ... incredible 10% off of their next FUE procedure, making ... transplant. , FUE—which stands for “Follicular Unit Extraction”—is an ... advantages over traditional “strip” Follicular Unit Transplantation (FUT). FUE, ...
(Date:11/26/2014)... 2014 Boxing Day is traditionally the ... receive gifts, known as a "Christmas box", from their ... With the coming of Boxing Day, some people may ... before every business opportunity, and it has recently announced ... site-wide promotion for its global customers. Then people can ...
(Date:11/26/2014)... Dallas, Texas (PRWEB) November 26, 2014 ... surgeon and Distinguished Teaching Professor in the ... Center, recently discussed facial fat compartments, fat grafting, ... Surgery, The Meeting," an annual conference held by ... importance and intricacies of this underlying facial structure ...
(Date:11/26/2014)... HealthDay Reporter WEDNESDAY, Nov. 26, 2014 ... understand what they,re saying, a new study suggests they are ... way. Past research has shown that dogs respond to ... and the emotional tone, said study author Victoria Ratcliffe. ... canine brain, according to Ratcliffe, a Ph.D. candidate at the ...
Breaking Medicine News(10 mins):Health News:Alzheimer's Association Shares Tips to Navigate the Holiday Season 2Health News:Alzheimer's Association Shares Tips to Navigate the Holiday Season 3Health News:Alzheimer's Association Shares Tips to Navigate the Holiday Season 4Health News:Alzheimer's Association Shares Tips to Navigate the Holiday Season 5Health News:FUE Special at Parsa Mohebi Hair Restoration This Holiday Season 2Health News:Tbdress.com: Best Boxing Day Sales For Ladies Worldwide 2Health News:Dr. Rod J. Rohrich Discusses Facelifts at ASPS Annual Assembly 2Health News:Dr. Rod J. Rohrich Discusses Facelifts at ASPS Annual Assembly 3Health News:Your Dog Really Is Listening to You 2Health News:Your Dog Really Is Listening to You 3
... of patients who contracted Hepatitis C in the 1980s had ... condition.// This is same as delayed is denied. ... McGuire, after studying documents obtained through the Freedom of Information ... and advise patients and that some had infected their partners. ...
... England is at its lowest ever with 8.5 deaths per 100,000 ... also noted that for the first time in 25 years there ... committing suicide. ,The British government had pledged to cut ... in 2002. The current report was jointly issued by the Department ...
... inflammation. According to a German clinical trail conducted by ... found that high doses of Vitamin D supplements inhibit ... function. The results of the study were published in ... researchers studied the effect of a high-dose vitamin D3 ...
... experts about the hearing loss caused by the MP3 ... without paying// any heed to those warnings. But sensing ... started limiting the volume on the devices. ,The ... damage to the ears associated with MP3 players. The ...
... to avoid controversial breast enlargement gel injections after six ... ,Fifty-three women from Hong Kong have complained of ... gel injected into their breasts. ,Six women ... after suffering severe complications from the operation, a spokesman ...
... an outbreak of malaria that claimed 35 lives and affected ... across Assam and medical teams are working on a war ... Bhumidhar Barman told IANS. ,Most of the casualties ... Lakhimpur, besides from areas bordering Bhutan. ,"Some 35 ...
Cached Medicine News:Health News:High Dose Of Vitamin D3 A Boon for Patients Suffering From Heart Failure 2Health News:Sensing The Health Hazard MP3 Makers Tone Down The Volume 2Health News:Malaria Claims 35 Lives In Assam 2
(Date:11/26/2014)... and NEW YORK ... As the leading distributor of market intelligence, ... new research report by IQ4I Research and Consultancy focusing ... To learn more about IQ4I Research visit: ... Active Pharmaceutical Ingredients Global Market – Forecast to ...
(Date:11/26/2014)... 25, 2014  At the American Dental Association,s Annual ... October, KaVo Kerr Group was honored to be part ... the opportunity to see and test the Best of ... deliver lectures on the latest developments in dental technology. ... new DEXIS CariVu Caries Detection Device and Kerr Demi ...
(Date:11/26/2014)... ANDOVER, Mass. , Nov. 25, 2014 ... Royal Philips (NYSE: PHG ... Food and Drug Administration (FDA) for its IQon ... spectral imaging. This first-of-its kind technology adds a new ... and offering the ability to characterize structures based on ...
Breaking Medicine Technology:MarketResearch.com: Active Pharmaceutical Ingredient Market to Reach $175 Billion by 2020 Says IQ4I Report 2MarketResearch.com: Active Pharmaceutical Ingredient Market to Reach $175 Billion by 2020 Says IQ4I Report 3KaVo Kerr Group Showcased in Pride Institute Technology Expo at ADA Annual Meeting 2KaVo Kerr Group Showcased in Pride Institute Technology Expo at ADA Annual Meeting 3Philips receives FDA 510(k) clearance for IQon Spectral CT 2Philips receives FDA 510(k) clearance for IQon Spectral CT 3
... China, July 21, 2011 /PRNewswire-Asia-FirstCall/ -- Mindray Medical International Limited ... marketer of medical devices worldwide, today announced that it will ... 30, 2011 after the U.S. market closes on August 8, ... 8:00 AM on August 9, 2011 U.S. Eastern Time (8:00 ...
... 21, 2011 Mettler-Toledo International Inc. (NYSE: MTD ... discuss the Company,s second-quarter results on Thursday, July 28, 2011 ... of the call, visit www.mt.com/investors on the Company,s ... August 1, 2011. METTLER TOLEDO is a ...
Cached Medicine Technology:Mindray to Report Second Quarter 2011 Financial Results on August 8, 2011 2
Jaffe tying forceps is very delicate with smooth jaws, straight, 6 mm long platform. For 8-0 to 11-0 sutures....
Curved shafts and tips with tying surfaces. Wide serrated handle with dull finish. Overall length 4.3 inches....
Curved shafts and tips with 7 mm tying platform. Serrated handle with polished finish. Overall length 4 inches....
Straight shafts with 5 mm tying platform. Wide handle with dull finish. Overall length 4.3 inches....
Medicine Products: