Navigation Links
Hepatitis C Treatment May Hamper Kids' Growth
Date:8/13/2012

MONDAY, Aug. 13 (HealthDay News) -- Children with hepatitis C who are treated with peginterferon alpha may experience growth-related side effects from the therapy, a new study reveals.

Although weight changes are reversible, many children's height for their age may be lower even after the treatment for hepatitis C virus (HCV) ends, the researchers found.

The study was published in the August issue of Hepatology.

"While HCV in children is typically mild, some cases do progress to cirrhosis and liver cancer," lead study author Dr. Maureen Jonas, director of the Center for Childhood Liver Disease and medical director of the Liver Transplant Program at Boston Children's Hospital, said in a journal news release.

"Treatment of HCV with peginterferon and ribavirin is approved for young children and offers the most benefit while liver disease is mild. However, there are concerns about the potential side effects of peginterferon therapy in children, which is the focus of our current study," Jonas explained.

The researchers followed 107 children (average age 11) with chronic hepatitis C, who participated in a study on the safety of hepatitis C treatments for an additional two years. Of these children, 55 percent were boys and 82 percent were white. When their treatment began, all of the children were of normal height, weight and body mass index (BMI), a measurement that takes both weight and height into account.

The children were divided into three groups based on how long they were treated with peginterferon: 24, 48 or 72 weeks. The study found that while on the therapy, some of the children had decreases in height, weight, and BMI scores compared to standard scores. Moreover, 33 percent of the children on the therapy for 48 weeks showed even larger decreases in height-for-age scores.

Children who had been treated with peginterferon for 48 or 72 weeks had lower average height scores at the two-year follow-up point than when treatment began. The children's height-for-age scores did not rebound as quickly as their weight and BMI. However, the children's diet and level of physical activity had not changed over the course of the study.

"Additional investigation of growth patterns is needed to determine long-term outcomes so that optimal timing of treatment can be determined for children with chronic HCV," Jonas concluded.

Although the study found an association with peginterferon treatment and changes in children's growth patterns, it did not show a cause-and-effect relationship.

More information

Visit the U.S. Centers for Disease Control and Prevention to learn more about hepatitis C.

-- Mary Elizabeth Dallas

SOURCE: Hepatology, news release, Aug. 9, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hepatitis A vaccination in children under 2 remains effective for 10 years
2. World Hepatitis Day - EASL calls on the United Nations to join the effort to tackle viral hepatitis
3. Smoking Tied to Risk for Hepatitis Return After Liver Transplant
4. NIH scientists identify likely predictors of hepatitis C severity
5. Herbal remedy used to treat hepatitis C proves ineffective, Penn study finds
6. Adding Vitamin B12 to Standard Drugs Might Help Fight Hepatitis C
7. Hepatitis C may increase deaths from both liver-related and other diseases
8. Milk Thistle of Little Help Against Hepatitis C: Study
9. Helper T cells, not killer T cells, might be responsible for clearing hepatitis A infection
10. Hepatitis C Virus Levels Higher in Certain Injection Drug Users
11. Current and former smokers at risk for recurrent hepatitis post-liver transplantation
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Hepatitis C Treatment May Hamper Kids' Growth
(Date:1/22/2017)... ... 22, 2017 , ... Zifam Pinnacle, an Australian company dedicated to providing a ... retail buyers at the January ECRM Trade Show in Hilton Head, SC. , Zifam ... standards in all of its creations to help create a more traditional and natural ...
(Date:1/21/2017)... ... 2017 , ... "ProDOF is the perfect set of tools for video editors that want to ... said Christina Austin - CEO of Pixel Film Studios. , Video editors using ProDOF ... of a DSLR racking focus from one area into the next. ProDOF comes with ...
(Date:1/21/2017)... ... January 21, 2017 , ... ... new medical office in Petaluma, located at 167 Lynch Creek Way. The Petaluma ... SRO sports medicine and rehabilitation services and on-site x-ray services. Two ...
(Date:1/20/2017)... ... 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh has posted a ... Yisrayl says this generation is a time like no other and society needs to understand ... Yisrayl says he does not want to sound like an old bible beater because religion ...
(Date:1/20/2017)... ... January 20, 2017 , ... ATP Science, an Australian-based ... recently attended the January ECRM Trade Show in Hilton Head, SC, benefiting from ... large range of supplements that keep the body functioning at its peak performance ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... Research and Markets has announced the ... and Future" report to their offering. ... This research service on the global ... and provides a snapshot of the key participants in the market. ... provided from 2016 to 2020. The market is expected to grow ...
(Date:1/19/2017)... Germany Cataract Surgery Devices Market Outlook ... Cataract Surgery Devices Market Outlook to 2022", provides key ... The report provides value, in millions of US dollars, ... segements - Phacoemulsification Equipment and Ophthalmic Viscoelastic Devices (OVD). ... shares data for each of these market segements, and ...
(Date:1/19/2017)... WASHINGTON , Jan. 19, 2017 Conference Call and ... VNDA ) today announced it will release results for the ... market closes. ... Vanda will host a conference call at 4:30 PM ET on ... quarter and full year 2016 financial results and other corporate activities. ...
Breaking Medicine Technology: