Navigation Links
Hepatitis C Treatment May Hamper Kids' Growth
Date:8/13/2012

MONDAY, Aug. 13 (HealthDay News) -- Children with hepatitis C who are treated with peginterferon alpha may experience growth-related side effects from the therapy, a new study reveals.

Although weight changes are reversible, many children's height for their age may be lower even after the treatment for hepatitis C virus (HCV) ends, the researchers found.

The study was published in the August issue of Hepatology.

"While HCV in children is typically mild, some cases do progress to cirrhosis and liver cancer," lead study author Dr. Maureen Jonas, director of the Center for Childhood Liver Disease and medical director of the Liver Transplant Program at Boston Children's Hospital, said in a journal news release.

"Treatment of HCV with peginterferon and ribavirin is approved for young children and offers the most benefit while liver disease is mild. However, there are concerns about the potential side effects of peginterferon therapy in children, which is the focus of our current study," Jonas explained.

The researchers followed 107 children (average age 11) with chronic hepatitis C, who participated in a study on the safety of hepatitis C treatments for an additional two years. Of these children, 55 percent were boys and 82 percent were white. When their treatment began, all of the children were of normal height, weight and body mass index (BMI), a measurement that takes both weight and height into account.

The children were divided into three groups based on how long they were treated with peginterferon: 24, 48 or 72 weeks. The study found that while on the therapy, some of the children had decreases in height, weight, and BMI scores compared to standard scores. Moreover, 33 percent of the children on the therapy for 48 weeks showed even larger decreases in height-for-age scores.

Children who had been treated with peginterferon for 48 or 72 weeks had lower average height scores at the two-year follow-up point than when treatment began. The children's height-for-age scores did not rebound as quickly as their weight and BMI. However, the children's diet and level of physical activity had not changed over the course of the study.

"Additional investigation of growth patterns is needed to determine long-term outcomes so that optimal timing of treatment can be determined for children with chronic HCV," Jonas concluded.

Although the study found an association with peginterferon treatment and changes in children's growth patterns, it did not show a cause-and-effect relationship.

More information

Visit the U.S. Centers for Disease Control and Prevention to learn more about hepatitis C.

-- Mary Elizabeth Dallas

SOURCE: Hepatology, news release, Aug. 9, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hepatitis A vaccination in children under 2 remains effective for 10 years
2. World Hepatitis Day - EASL calls on the United Nations to join the effort to tackle viral hepatitis
3. Smoking Tied to Risk for Hepatitis Return After Liver Transplant
4. NIH scientists identify likely predictors of hepatitis C severity
5. Herbal remedy used to treat hepatitis C proves ineffective, Penn study finds
6. Adding Vitamin B12 to Standard Drugs Might Help Fight Hepatitis C
7. Hepatitis C may increase deaths from both liver-related and other diseases
8. Milk Thistle of Little Help Against Hepatitis C: Study
9. Helper T cells, not killer T cells, might be responsible for clearing hepatitis A infection
10. Hepatitis C Virus Levels Higher in Certain Injection Drug Users
11. Current and former smokers at risk for recurrent hepatitis post-liver transplantation
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Hepatitis C Treatment May Hamper Kids' Growth
(Date:6/27/2017)... ... June 27, 2017 , ... Two residents from the ... a video designed to encourage lawmakers to protect Medicaid funding. , The ... Assisted Living (AHCA/NCAL), highlights the story of Chuck and Cathy Schwarz, a couple who ...
(Date:6/27/2017)... York, NY (PRWEB) , ... June 27, 2017 ... ... and marketing experts to contribute to an upcoming case studies guidebook. This guidebook ... her organization. , This book will include articles, case studies and how-to’s that ...
(Date:6/27/2017)... ... June 27, 2017 , ... ... Foundation Fundraiser hygiene symposium in Mystic, CT. Covering the process and maintenance strategies ... experience in these popular periodontal procedures. Drs. Toback and Urbanski practice as experienced ...
(Date:6/27/2017)... ... ... Hammer Strength, the world’s leading performance strength training brand, and the National ... the NBSCA Strength & Conditioning Coach of the Year. , In its 11th ... select the coach who embodies the highest level of excellence and outstanding service to ...
(Date:6/27/2017)... , ... June 27, 2017 , ... ... . Orthodontics is a dental specialty that focuses on treating alignment and occlusion ... improved aesthetics and function. , North Hollywood dentist , Dr. Garemani, ...
Breaking Medicine News(10 mins):
(Date:5/30/2017)... , May 30, 2017 Hill-Rom Holdings, Inc. (NYSE: ... Annual Global Healthcare Conference on Tuesday, June 13, 2017, in ... Greisch , Hill-Rom,s president and chief executive officer, is scheduled ... live audio webcast can be accessed at http://ir.hill-rom.com/events.cfm . ... of the live event through September 13, 2017. ...
(Date:5/29/2017)...  Cellect Biotechnology Ltd. (NASDAQ: APOP ; TASE: ... functional selection of stem cells, today provided a corporate ... ended March 31 st , 2017. ... first quarter of 2017," said Dr. Shai Yarkoni, Chief ... treatment of the first blood cancer patient in the ...
(Date:5/26/2017)... , May 25, 2017  In response to ... , Direct Relief is working with Pfizer to ... available at no cost to community health centers, free ... providers nationwide. "Pfizer has a long-standing ... medicines and ensuring patient safety through educational activities," said ...
Breaking Medicine Technology: