Navigation Links
Hepatitis C Treatment May Hamper Kids' Growth
Date:8/13/2012

MONDAY, Aug. 13 (HealthDay News) -- Children with hepatitis C who are treated with peginterferon alpha may experience growth-related side effects from the therapy, a new study reveals.

Although weight changes are reversible, many children's height for their age may be lower even after the treatment for hepatitis C virus (HCV) ends, the researchers found.

The study was published in the August issue of Hepatology.

"While HCV in children is typically mild, some cases do progress to cirrhosis and liver cancer," lead study author Dr. Maureen Jonas, director of the Center for Childhood Liver Disease and medical director of the Liver Transplant Program at Boston Children's Hospital, said in a journal news release.

"Treatment of HCV with peginterferon and ribavirin is approved for young children and offers the most benefit while liver disease is mild. However, there are concerns about the potential side effects of peginterferon therapy in children, which is the focus of our current study," Jonas explained.

The researchers followed 107 children (average age 11) with chronic hepatitis C, who participated in a study on the safety of hepatitis C treatments for an additional two years. Of these children, 55 percent were boys and 82 percent were white. When their treatment began, all of the children were of normal height, weight and body mass index (BMI), a measurement that takes both weight and height into account.

The children were divided into three groups based on how long they were treated with peginterferon: 24, 48 or 72 weeks. The study found that while on the therapy, some of the children had decreases in height, weight, and BMI scores compared to standard scores. Moreover, 33 percent of the children on the therapy for 48 weeks showed even larger decreases in height-for-age scores.

Children who had been treated with peginterferon for 48 or 72 weeks had lower average height scores at the two-year follow-up point than when treatment began. The children's height-for-age scores did not rebound as quickly as their weight and BMI. However, the children's diet and level of physical activity had not changed over the course of the study.

"Additional investigation of growth patterns is needed to determine long-term outcomes so that optimal timing of treatment can be determined for children with chronic HCV," Jonas concluded.

Although the study found an association with peginterferon treatment and changes in children's growth patterns, it did not show a cause-and-effect relationship.

More information

Visit the U.S. Centers for Disease Control and Prevention to learn more about hepatitis C.

-- Mary Elizabeth Dallas

SOURCE: Hepatology, news release, Aug. 9, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hepatitis A vaccination in children under 2 remains effective for 10 years
2. World Hepatitis Day - EASL calls on the United Nations to join the effort to tackle viral hepatitis
3. Smoking Tied to Risk for Hepatitis Return After Liver Transplant
4. NIH scientists identify likely predictors of hepatitis C severity
5. Herbal remedy used to treat hepatitis C proves ineffective, Penn study finds
6. Adding Vitamin B12 to Standard Drugs Might Help Fight Hepatitis C
7. Hepatitis C may increase deaths from both liver-related and other diseases
8. Milk Thistle of Little Help Against Hepatitis C: Study
9. Helper T cells, not killer T cells, might be responsible for clearing hepatitis A infection
10. Hepatitis C Virus Levels Higher in Certain Injection Drug Users
11. Current and former smokers at risk for recurrent hepatitis post-liver transplantation
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Hepatitis C Treatment May Hamper Kids' Growth
(Date:5/6/2016)... ... May 06, 2016 , ... Online HR/benefits platforms offer a ... the game for traditional brokers and health plans. “ The Rapid Emergence of Online ... from Atlantic Information Services, Inc. (AIS), will offer an accurate picture of online benefits ...
(Date:5/6/2016)... ... ... From the Speaker Podium to the Exhibit Floor at Booth#514, Worldwide Leading Contact Center ... at SpeechTek 2016 Event, taking place May 23-25 at the Omni Shoreham in Washington ... “5 Customer Engagement Strategies to improve Customer Satisfaction in your Contact Center” on May ...
(Date:5/6/2016)... NY (PRWEB) , ... May 06, 2016 , ... The ... & Resort on the north end of the island close to the town famous ... 17th- August 10th 2016. , “We continue to have an amazing experience in ...
(Date:5/6/2016)... ... May 06, 2016 , ... Multiple award winning plumbing company ... over 35 years. Maintaining core values of exceptional customer service, quality work at reasonable ... a leading name in San Diego plumbing, and other services including heating & air ...
(Date:5/6/2016)... ... 2016 , ... Few events in healthcare changed the landscape ... cost despite its potential to wipe out a silent killer, hepatitis C virus. ... called direct-acting antivirals (DAAs)—have created fallout in the courts and state governments. Advocates ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... Research and Markets has ... Ischemic Stroke Market and Competitive Landscape Highlights ...      (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ) ... Market and Competitive Landscape Highlights 2016, provides ... products, Acute Ischemic Stroke epidemiology, Acute Ischemic ...
(Date:5/4/2016)... , May 4, 2016 ... addition of the  "Global Actinic Keratosis Market ... to their offering.       (Logo: ... Keratosis Market and Competitive Landscape Highlights 2016, ... products, Actinic Keratosis epidemiology, Actinic Keratosis market ...
(Date:5/3/2016)... PUNE, India , May 4, 2016 /PRNewswire/ ... report spreads across 154 pages, profiling 09 key ... It is a professional and in-depth study on ... providing a basic overview of the industry including ... Insulin Needles market analysis is provided for the ...
Breaking Medicine Technology: