Navigation Links
Henry Ford Hospital study: hVISA linked to high mortality
Date:9/12/2010

A MRSA infection with a reduced susceptibility to the potent antibiotic drug vancomycin is linked to high mortality, according to a Henry Ford Hospital study.

Researchers found that patients who contracted a MRSA infection with heteroresistance, called hVISA, stayed in the hospital longer, were more likely to have the infection return after 90 days, and were twice as likely to die from it after 90 days than patients who do not have hVISA.

The study is being presented Sunday at the 50th annual Interscience Conference on Antimicrobial Agents and Chemotherapy in Boston.

"Based on our findings, we recommend that hospitals consider routine testing for hVISA," says Katherine Reyes, M.D., a Henry Ford Hospital Internal Medicine physician and the study's lead author. "It remains controversial how differently we will manage these patients upfront. Close follow-up on these patients to make sure their infection is resolved or controlled may save lives."

MRSA, or Methicillin-resistant Staphylococcus aureus, is a bacterium that is resistant to common antibiotics like penicillin. It can cause skin, bloodstream and surgical wound infections and pneumonia. The majority of infections occur among patients in hospitals or other health care settings, though a growing number of infections are being acquired by otherwise healthy people outside those settings.

MRSA strains can be resistant to many drugs, though they are typically susceptible to the antibiotic vancomycin. MRSA infections are often treated with vancomycin administered intravenously.

The study followed 521 patients with MRSA bloodstream infections who were admitted between January 2006 to September 2009 to Henry Ford, an 805-bed tertiary care hospital, education and research complex in Detroit. These infections were screened for heteroresistance, and 19 hVISA cases were identified.

Dr. Reyes and researchers then compared characteristics and outcomes of the 19 hVISA patients against 19 non-hVISA patients, eliminating such factors as age, source of infection and level of sickness. The results:

  • Six hVISA patients died within 30 days compared to three non-hVISA patients.
  • Twelve hVISA patients died within 90 days compared to six non-hVISA patients.
  • Five hVISA patients saw their infection return after 90 days compared to zero for non-hVISA patients.
  • hVISA patients stayed on average four more days in the hospital than non-hVISA patients.
  • hVISA patients were more likely to have received vancomycin in the past.


'/>"/>

Contact: David Olejarz
dolejar1@hfhs.org
313-874-4094
Henry Ford Health System
Source:Eurekalert

Related medicine news :

1. The Henry Ford Production System LEAN training for health care
2. Henry Ford Hospital study: Donor Risk Index does not impact outcomes on a small scale
3. Healthy U Chosen as Exclusive Concessions Provider for McHenry's 1st Annual Kicks 4 Kids Youth Charity Soccer Tournament
4. Sung-Cheng (Henry) Huang receives 2010 Benedict Cassen Prize for Research in Nuclear Medicine
5. Henry Gabelnick receives lifetime achievement award
6. Henry Ford Hospital study: Fewer infections with new heart-pump implant
7. Henry Ford Hospital: New left-side heart pump improves right-side heart function
8. Henry Ford Hospital study: Less prep needed for colonoscopy
9. Henry Ford Health System goes radical: Creating the hospital of the future
10. Henry Ford Hospital atudy: Hepatitis C infection doubles risk for kidney cancer
11. Henry Ford Hospital study: Shoulder function not fully restored after surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2017)... ... March 29, 2017 , ... The Wall Centre Dental team ... patients from Burnaby, BC. Patients in need of experienced orthodontics, laser dentistry, porcelain ... the esteemed team at Wall Centre Dental. Drs. Parviz Roshan, Siamak Tehrani, Milton ...
(Date:3/29/2017)... ... March 29, 2017 , ... ... developing an ANSI-approved, consensus-based American National Standard for Good Manufacturing Practices (GMPs) ... first ANSI-approved GMP standard for dietary supplements this spring, is hiring an ...
(Date:3/29/2017)... PA (PRWEB) , ... March 29, 2017 , ... ... hassles associated with wearing oral braces. "The rubber bands used in conjunction with ... said, "so I decided to design a way to prevent this problem." The ...
(Date:3/29/2017)... ... 29, 2017 , ... Hamlin Dental Group, multi-location dental office in North ... Dental lasers are safe and effective options, and can be used alone or in ... overall quality of care. , Dr. Hamid Reza of Hamlin Dental Group offers other ...
(Date:3/29/2017)... (PRWEB) , ... March 29, 2017 , ... AvePoint ... seventh North American office location in Richmond, Virginia, located at the Riverfront Plaza, 901 ... attended by Lieutenant Governor of Virginia Ralph S. Northam and Mayor of Richmond Levar ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... Research and Markets has announced the addition ... their offering. ... The global lifestyle drugs market to grow at a CAGR of ... Lifestyle Drugs Market 2017-2021, has been prepared based on an in-depth ... market landscape and its growth prospects over the coming years. The ...
(Date:3/29/2017)... March 29, 2017 Varian Medical Systems (NYSE: ... for the second quarter of fiscal year 2017 following the ... news release will be followed by a teleconference available to ... and a link to the conference call webcast will be ... access the teleconference call and replay: ...
(Date:3/29/2017)... , March 29, 2017  Designers of primary cell ... solution size by 50% and extend battery life with ... management integrated circuit (PMIC) from Maxim Integrated Products, Inc. ... a low input voltage of just 0.7V for new ... Silver Oxide, as well as the more common Alkaline ...
Breaking Medicine Technology: