Navigation Links
Helping preterm babies get the best start
Date:6/27/2011

Babies born prematurely could be at greater risk of developing kidney diseases later in life according to a landmark study investigating the impacts of preterm birth on kidney development.

The Monash University study is identifying new strategies for minimising the consequences of being born preterm, which accounts for around eight per cent of births each year in Australia.

By comparing the kidneys of babies born prematurely with those born after the full nine-month gestation, the research team, led by Associate Professor Jane Black from the Department of Anatomy and Cell Biology, identified that preterm babies had far fewer nephrons the 'building blocks' that make our kidneys.

"An average person has around 800,000 to 1.5 million nephrons and the number we have at birth is the number we have for life," Associate Professor Black said.

"We have shown that babies born preterm have less nephrons, in the range of 400,000 600,000. This is because nephron development occurs in the last few weeks of pregnancy, so babies born preterm have not had time to complete the developmental process."

"Even moderate preterm babies, those born within four weeks of full gestation, who were previously considered to have achieved 'normal' development, were found to have far fewer nephrons and underdeveloped kidneys."

Associate Professor Black said the findings were of critical importance because of the known link between having fewer nephrons and renal, or kidney, diseases.

"The more nephrons you have the more 'solid' a structure your kidneys will have. When we look at kidneys that have fewer nephrons, abnormalities are present, which indicates that preterm babies could be much more susceptible to renal disease and possible kidney failure later in life," Associate Professor Black said.

"Particularly in the last 30 years, we have had great successes with preterm births and today even babies born 26 weeks premature have an 80 per cent chance of survival. Preterm babies now account for around eight per cent of births in Australia and 12-14 per cent in the USA."

"Because the improvements in survival rates are only recent, we have not yet witnessed the impact of premature births on the health system."

Associate Professor Black has received two prestigious grants from the National Health and Medical Research Council (NHMRC) administered by Monash University.

"The NHMRC funding will enable Monash researchers to study the development of kidneys and hearts in preterm babies," Associate Professor Black said.

"With the kidney studies, our aim is to develop strategies that will ensure these babies have the highest number of nephrons possible, in order to give them the best start in life."

"We need to know the things that restrict nephron development and are looking at a range of factors, including blood pressure, respiration, medications taken during pregnancy, and care following birth."

"We are also working with Indigenous communities in the Northern Territory so we can make a comparison between the renal development of Indigenous and non-Indigenous babies. This is timely as Indigenous people have 17 times greater incidence of renal disease than the non-Indigenous population," said Associate Professor Black.


'/>"/>

Contact: Monash Media and Communciations
media@monash.edu
61-399-034-840
Monash University
Source:Eurekalert

Related medicine news :

1. Helping deaf people to enjoy music again
2. Helping the aged during natural disasters
3. Sedentary Jobs Helping to Drive Obesity Epidemic
4. New UTHealth trial aimed at helping pregnant women stop smoking
5. Wii key to helping kids balance
6. U. of Colorado study shows acupressure effective in helping to treat traumatic brain injury
7. Helping Fellow Addicts Can Help Maintain Sobriety
8. Helping others helps alcoholics stay on the road to recovery, Case Western Reserve shows
9. FSU researchers helping electric-wheelchair users move more easily
10. School-based program effective in helping adolescents
11. States Urged to Fill Gap in Helping Smokers Quit
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2017)... Plano, TX (PRWEB) , ... July 27, 2017 ... ... technology and outsourced services, announces the internal promotion of Elrene Clinkscales to Vice ... Operations – Claims & Remittance Management, reporting to Derek Morkel, chief executive officer ...
(Date:7/27/2017)... ... 2017 , ... Team Novo Nordisk, the world’s first all-diabetes professional cycling team, ... a stagiaire for the remainder of the 2017 season. One of our best development ... Tour of Utah. , “Every season we are excited to move an athlete from ...
(Date:7/26/2017)... ... July 26, 2017 , ... Written By: Ashley D. Beall, ... in drug therapy for patients living with relapsing and primary multiple sclerosis that ... cell targeted therapy that has been proven to significantly reduce signs of disease ...
(Date:7/26/2017)... ... July 26, 2017 , ... “We are dentists and we thought there ... Jose, Calif., “so we invented the MAGNETIC/ LOCK BRACKETS.” , The patent-pending MAGNETIC/ LOCK ... In doing so, it offers an effective alternative to traditional braces. As a result, ...
(Date:7/26/2017)... ... July 26, 2017 , ... “We are thrilled to be ... for patients to schedule an appointment online in real time,” said Keith English, LocalMed ... Smiles provider directory will bring more Six Month Smiles patients to their providers.” , ...
Breaking Medicine News(10 mins):
(Date:7/27/2017)...  West Pharmaceutical Services, Inc. (NYSE: WST ... 2017 and updated financial guidance for the full-year 2017. ... Reported net sales of $397.6 million, ... Net sales at constant currency (organic) grew by 3.9%. ... compared to $0.60 in the prior-year quarter. Second-quarter 2017 ...
(Date:7/26/2017)... Aesthetics, a leading medical aesthetic clinic in Singapore ... skin conditions from the inside. The natural process of ... skin becomes more transparent due to the thinning of the epidermis. Over ... the sun contributes to aging skin, causing age spots and other ... ...
(Date:7/26/2017)... 26, 2017 The Galien Foundation announced ... USA Award Nominees. Counted among the global ... recognizes outstanding biomedical and technology product achievement that improves the ... qualify, each candidate must be U.S. Food and Drug Administration ... demonstrate tremendous potential to impact human health. Sales data are ...
Breaking Medicine Technology: