Navigation Links
Helping preterm babies get the best start
Date:6/27/2011

Babies born prematurely could be at greater risk of developing kidney diseases later in life according to a landmark study investigating the impacts of preterm birth on kidney development.

The Monash University study is identifying new strategies for minimising the consequences of being born preterm, which accounts for around eight per cent of births each year in Australia.

By comparing the kidneys of babies born prematurely with those born after the full nine-month gestation, the research team, led by Associate Professor Jane Black from the Department of Anatomy and Cell Biology, identified that preterm babies had far fewer nephrons the 'building blocks' that make our kidneys.

"An average person has around 800,000 to 1.5 million nephrons and the number we have at birth is the number we have for life," Associate Professor Black said.

"We have shown that babies born preterm have less nephrons, in the range of 400,000 600,000. This is because nephron development occurs in the last few weeks of pregnancy, so babies born preterm have not had time to complete the developmental process."

"Even moderate preterm babies, those born within four weeks of full gestation, who were previously considered to have achieved 'normal' development, were found to have far fewer nephrons and underdeveloped kidneys."

Associate Professor Black said the findings were of critical importance because of the known link between having fewer nephrons and renal, or kidney, diseases.

"The more nephrons you have the more 'solid' a structure your kidneys will have. When we look at kidneys that have fewer nephrons, abnormalities are present, which indicates that preterm babies could be much more susceptible to renal disease and possible kidney failure later in life," Associate Professor Black said.

"Particularly in the last 30 years, we have had great successes with preterm births and today even babies born 26 weeks premature have an 80 per cent chance of survival. Preterm babies now account for around eight per cent of births in Australia and 12-14 per cent in the USA."

"Because the improvements in survival rates are only recent, we have not yet witnessed the impact of premature births on the health system."

Associate Professor Black has received two prestigious grants from the National Health and Medical Research Council (NHMRC) administered by Monash University.

"The NHMRC funding will enable Monash researchers to study the development of kidneys and hearts in preterm babies," Associate Professor Black said.

"With the kidney studies, our aim is to develop strategies that will ensure these babies have the highest number of nephrons possible, in order to give them the best start in life."

"We need to know the things that restrict nephron development and are looking at a range of factors, including blood pressure, respiration, medications taken during pregnancy, and care following birth."

"We are also working with Indigenous communities in the Northern Territory so we can make a comparison between the renal development of Indigenous and non-Indigenous babies. This is timely as Indigenous people have 17 times greater incidence of renal disease than the non-Indigenous population," said Associate Professor Black.


'/>"/>

Contact: Monash Media and Communciations
media@monash.edu
61-399-034-840
Monash University
Source:Eurekalert

Related medicine news :

1. Helping deaf people to enjoy music again
2. Helping the aged during natural disasters
3. Sedentary Jobs Helping to Drive Obesity Epidemic
4. New UTHealth trial aimed at helping pregnant women stop smoking
5. Wii key to helping kids balance
6. U. of Colorado study shows acupressure effective in helping to treat traumatic brain injury
7. Helping Fellow Addicts Can Help Maintain Sobriety
8. Helping others helps alcoholics stay on the road to recovery, Case Western Reserve shows
9. FSU researchers helping electric-wheelchair users move more easily
10. School-based program effective in helping adolescents
11. States Urged to Fill Gap in Helping Smokers Quit
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... ... 2016 , ... Delta Dental of California and its affiliated companies announced today ... Radine, who recently retired as president and CEO of Delta Dental of California and ... the Year , helped lead the effort to raise funds for studies to strengthen ...
(Date:2/8/2016)... , ... February 08, 2016 , ... Discover the Rocky ... over 1,400 booths and 700 companies. Attendees also get to see the most ... Colorado Garden & Home Show , at the Colorado Convention Center - 700 14th ...
(Date:2/8/2016)... , ... February 08, 2016 , ... Guruji Mahendra Kumar ... 10th and 11th, 2016 in honor of his birthday on February 10th. During ... Mahendra Trivedi is known by over 250,000 people from over 40 different countries ...
(Date:2/7/2016)... ... February 07, 2016 , ... ... empowers employers and organizations with the tools and information to lower the costs, ... to cut the cost of providing employee healthcare benefits by as much as ...
(Date:2/6/2016)... ... , ... Shark Finds and Kevin Harrington, along with the Product ... with Belly Bands. , Having a dog is great—except when it wets every couch, ... nothing works, get Belly Bands, the easiest way to stop dogs from wetting ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... --> ... Market Research titled, "World Synthetic Biology ... the world synthetic biology market to be $5.2 ... segment would continue to lead the market until ... held around half of the market share in ...
(Date:2/5/2016)... ANGELES , Feb. 5, 2016  Redwood Scientific ... a new product designed to help women balance their ... strip delivery technology. Jason Cardiff , ... will be able to help the millions of women ... from the effects of imbalanced hormones. Our research and ...
(Date:2/5/2016)... 2016  Aralez Pharmaceuticals Inc. ("Aralez") today announced the ... Tribute Pharmaceuticals Canada Inc. ("Tribute") following approval of the ... The combined company will operate under Aralez Pharmaceuticals Inc. ... Canada , Ireland ... Under the terms of the Agreement and Plan of ...
Breaking Medicine Technology: