Navigation Links
Helping preterm babies get the best start
Date:6/27/2011

Babies born prematurely could be at greater risk of developing kidney diseases later in life according to a landmark study investigating the impacts of preterm birth on kidney development.

The Monash University study is identifying new strategies for minimising the consequences of being born preterm, which accounts for around eight per cent of births each year in Australia.

By comparing the kidneys of babies born prematurely with those born after the full nine-month gestation, the research team, led by Associate Professor Jane Black from the Department of Anatomy and Cell Biology, identified that preterm babies had far fewer nephrons the 'building blocks' that make our kidneys.

"An average person has around 800,000 to 1.5 million nephrons and the number we have at birth is the number we have for life," Associate Professor Black said.

"We have shown that babies born preterm have less nephrons, in the range of 400,000 600,000. This is because nephron development occurs in the last few weeks of pregnancy, so babies born preterm have not had time to complete the developmental process."

"Even moderate preterm babies, those born within four weeks of full gestation, who were previously considered to have achieved 'normal' development, were found to have far fewer nephrons and underdeveloped kidneys."

Associate Professor Black said the findings were of critical importance because of the known link between having fewer nephrons and renal, or kidney, diseases.

"The more nephrons you have the more 'solid' a structure your kidneys will have. When we look at kidneys that have fewer nephrons, abnormalities are present, which indicates that preterm babies could be much more susceptible to renal disease and possible kidney failure later in life," Associate Professor Black said.

"Particularly in the last 30 years, we have had great successes with preterm births and today even babies born 26 weeks premature have an 80 per cent chance of survival. Preterm babies now account for around eight per cent of births in Australia and 12-14 per cent in the USA."

"Because the improvements in survival rates are only recent, we have not yet witnessed the impact of premature births on the health system."

Associate Professor Black has received two prestigious grants from the National Health and Medical Research Council (NHMRC) administered by Monash University.

"The NHMRC funding will enable Monash researchers to study the development of kidneys and hearts in preterm babies," Associate Professor Black said.

"With the kidney studies, our aim is to develop strategies that will ensure these babies have the highest number of nephrons possible, in order to give them the best start in life."

"We need to know the things that restrict nephron development and are looking at a range of factors, including blood pressure, respiration, medications taken during pregnancy, and care following birth."

"We are also working with Indigenous communities in the Northern Territory so we can make a comparison between the renal development of Indigenous and non-Indigenous babies. This is timely as Indigenous people have 17 times greater incidence of renal disease than the non-Indigenous population," said Associate Professor Black.


'/>"/>

Contact: Monash Media and Communciations
media@monash.edu
61-399-034-840
Monash University
Source:Eurekalert

Related medicine news :

1. Helping deaf people to enjoy music again
2. Helping the aged during natural disasters
3. Sedentary Jobs Helping to Drive Obesity Epidemic
4. New UTHealth trial aimed at helping pregnant women stop smoking
5. Wii key to helping kids balance
6. U. of Colorado study shows acupressure effective in helping to treat traumatic brain injury
7. Helping Fellow Addicts Can Help Maintain Sobriety
8. Helping others helps alcoholics stay on the road to recovery, Case Western Reserve shows
9. FSU researchers helping electric-wheelchair users move more easily
10. School-based program effective in helping adolescents
11. States Urged to Fill Gap in Helping Smokers Quit
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... , ... Source Vitál Apothecary, a skin and body care company dedicated to ... had a successful visit to the 2017 ECRM Diet, Vitamin & Sports Nutrition Conference ... the nutritional, sports and health industries a chance to meet in private sessions with ...
(Date:1/20/2017)... ... January 20, 2017 , ... Lice Troopers, the lice ... in families with school-aged children since the holiday season. , “It happens every ... their families, sharing hugs and taking photos, which is the head-to-head gateway that lice ...
(Date:1/20/2017)... boca raton florida (PRWEB) , ... January 20, 2017 , ... ... trial at the Dana Farber Cancer Institute. For Betsy, the clinical trial has ... and her cancer has not worsened. , Betsy Brauser was diagnosed with ovarian ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... “Mary Magdalene: ... the mysterious life of the woman who witnessed Jesus Christ firsthand. “Mary Magdalene: Grace ... denizen, who spent her career as an educator interacting with countless women who had ...
(Date:1/20/2017)... ... January 20, 2017 , ... “I Forgive You”: a fine examination of how ... You” is the creation of published author, Stephen Miller, who, for over ten long years ... given to him. Born in Trinidad and Tobago, he has been serving the Lord for ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... Avillion LLP, a co-developer and financier of late-stage pharmaceutical ... MBA as Chief Medical Officer. Dr Weinberg will be based in ... ... more than 17 years as a pharmaceutical and biotech executive with ... the course of his career, he has interfaced with the US ...
(Date:1/19/2017)... YORK , Jan. 19, 2017 The ... provides understanding and access to partnering deals and agreements ... - Trends in partnering deals - Top deals by ... stage of development, technology type The report provides ... entered into by the world,s leading healthcare companies. ...
(Date:1/19/2017)... 19, 2017 This report on the opioid ... scenario of the global market. Large number of chronic ... chronic constipation is a major side effect of consumption ... novel targeted therapy has been prescribed to treat opioid ... targeted medicines, and growing awareness about the therapy are ...
Breaking Medicine Technology: