Navigation Links
Height May Boost Prostate Cancer Risk, Study Suggests

But the findings could be pure chance, one expert says

WEDNESDAY, Sept. 3 (HealthDay News) -- Taller men are at greater risk for prostate cancer and more likely to have cancer that progresses quickly, a new British study suggests.

The researchers doubt that height itself is the reason for the increased risk, but it may serve as a marker for something biological associated with developing cancer.

And other cancer experts said other risk factors for the disease are far more significant than being tall.

"We believe that factors that influence height -- not height itself -- could also influence cancer, said lead study researcher Luisa Zuccolo, of the University of Bristol Department of Social Medicine. "One plausible mechanism behind this association could be the insulin-like growth factor-1 system, which new lines of inquiry should address."

The findings were published in the September issue of the journal Cancer Epidemiology, Biomarkers & Prevention.

For the study, Zuccolo's team collected data on more than 9,000 men with and without prostate cancer and reviewed 57 relevant studies. The researchers found that the risk of developing prostate cancer increased about 6 percent for every 3.9 inches in height above the shortest men in the study. The average height of the men in the study was 5 feet, 7 inches.

In other words, a man who's a foot taller than the shortest person in the study would have a 19 percent increased risk of developing prostate cancer. The statistical data supporting this finding was weak, the researchers noted.

However, the researchers did find stronger evidence that height was associated with more aggressive tumors. For every 3.9 inches of increased height, the risk of a high-grade tumor rose 23 percent, Zuccolo's group found.

Compared with the main risk factors for prostate cancer -- such as aging, ethnicity and a family history of the disease -- the magnitude of the additional risk of being taller is small, Zuccolo said.

"We do not believe that height should interfere with preventive or clinical decisions in managing prostate cancer," Zuccolo said. "However, although not yet directly transferrable to medical practice, results from this research are of great scientific interest, especially given that so little is known of preventable causes of prostate cancer."

Dr. Anthony D'Amico, chief of radiation oncology at Brigham and Women's Hospital in Boston, said the study findings may be due to chance and not represent a real association.

"When you do a study like this, where you look at a very common attribute like height, eye color or skin color, and then you look at a very common disease like prostate cancer, you can find association that may just be by chance," he said.

There may be an association between height and a high-grade prostate cancer, D'Amico added. "But that association should not be taken to mean that if you are tall that there is something about being tall and getting high-grade prostate cancer. It could simply be that being tall is a surrogate for something else biological, which may be what is causing the effect."

"I don't think that this study convinces me, or makes me conclude that height in and of itself is a risk factor, and we should start screening earlier in men who are above a certain height," he said.

Dr. Stephen Freedland, an associate professor of urology and pathology and director of outcomes and translational research at the Duke Prostate Center at Duke University Medical Center, thinks other risk factors for prostate cancer are much more important than height.

"This is something I'd hate to see people get all worried about," he said. "If you eat right, take care of yourself, prevent yourself from being obese, I think you are doing the best you can. Everyone, short or tall, should be checked regularly."

More information

Learn more about prostate cancer from the American Cancer Society.

SOURCES: Luisa Zuccolo, M.Sc., Department of Social Medicine, the University of Bristol, United Kingdom; Anthony D'Amico, M.D., Ph.D., chief, radiation oncology, Brigham and Women's Hospital, Boston; Stephen Freedland, M.D., associate professor of urology and pathology, director of outcomes and translational research, Urological Surgery, Duke Prostate Center, Duke University Medical Center, Durham, N.C.; September 2008, Cancer Epidemiology, Biomarkers & Prevention

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. High and mighty: first common height gene identified by researchers behind obesity gene finding
2. Metabolic syndrome heightens risk for development of uric-acid kidney stones
3. Sun Safety Awareness Reaches New Heights at Plano Hot Air Balloon Festival
4. The American Liver Foundation Encourages Heightened Awareness of Hepatitis B and C in Light of Recent Events in the News
5. Test for Life Marks World AIDS Day, Heightens Awareness of HIV/AIDS Testing in the U.S.
6. Night Shift Work May Heighten Risk for Cancer
7. High Meat Consumption Linked to Heightened Cancer Risk
8. Genes Linked to Height Also Tied to Osteoarthritis Risk
9. CCH Outlines 10 Steps to Keeping the Workplace Healthy in the Height of Flu Season
10. White Hat Brands Takes Dog On It! Fortified Juice Beverage for Kids to New Heights
11. Height of Pitchers Mound Can Strain Shoulders
Post Your Comments:
(Date:11/25/2015)... ... 25, 2015 , ... Finnleo, a leader in the traditional and far-infrared sauna ... and far-infrared saunas. , For traditional saunas, Finnleo is offering 20% ... wood, and Finnleo uses only European Grade A Nordic White Spruce from sustainably grown ...
(Date:11/25/2015)... ... November 25, 2015 , ... TyloHelo Inc , North ... , Sauna accessories help improve the bather experience in the sauna, and the ... for the purist looking for simplicity in design to accessories that encourage a ...
(Date:11/25/2015)... ... November 26, 2015 , ... Ministers, senior ... (EU), ANDI Pan African Centres of Excellence, and public R&D institutions, civil societies ... the opening of the 5th African Network for Drugs and Diagnostics Innovation, ANDI, ...
(Date:11/25/2015)... ... November 25, 2015 , ... For the first time, ... Two Organizations, One Beat ” campaign. The partnership between the two groups began in ... in MAP International’s cause. , MAP International was founded in 1954 and is an ...
(Date:11/25/2015)... ... 2015 , ... Lakeview Health, a Jacksonville-based drug and alcohol ... and show through pictures what a positive difference it makes. The social media ... hashtag #FacesOfGratitude on their Facebook, Twitter, and Instagram accounts. Short stories can ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015 On ... first federal bellwether trial against Wright Medical Technology, ... to their Conserve metal-on-metal hip implant device, awarded ... Following a two week trial and three days ... metal-on-metal hip device was defectively designed and unreasonably ...
(Date:11/25/2015)...  Trovagene, Inc. (NASDAQ: TROV ), a developer ... Officer Antonius Schuh, Ph.D., is scheduled to present a ... Jaffray Healthcare Conference. th Annual Piper ... in New York on Tuesday, ... will be available for one-on-one meetings during the conference. ...
(Date:11/25/2015)... , November 25, 2015 ... of self-monitoring blood glucose devices was valued at $11,171.1 ... with a CAGR of 5.7% during 2015 - 2022. ... population and increasing prevalence of diabetes. In addition, the ... care is also contributing to the growth of the ...
Breaking Medicine Technology: