Navigation Links
Heavy birthweight babies twice as likely to develop rheumatoid arthritis
Date:6/29/2008

Heavy birthweight female babies are twice as likely to develop rheumatoid arthritis in adulthood as their average birthweight peers, suggests research published ahead of print in the Annals of the Rheumatic Diseases.

The results support the fetal origin of disease theory, which argues that certain conditions and diseases in adult life are programmed by factors during the pregnancy.

Diabetes, coronary heart disease, and high blood pressure, for example, have been linked to low birthweight, while an increased risk of breast cancer and leukaemia have been linked to high birthweight.

The findings are based on over 87,000 women taking part in the US Nurses' Health Study between 1976 and 2002. All the participants were aged between 30 and 55 at the start of the study in 1976.

Every two years, the women were quizzed about their health, lifestyle, and family illness. And in 1992 they were asked to provide information on their birthweight.

During the study period, 619 women were diagnosed with rheumatoid arthritis for the first time.

Women who weighed more than 4.54 kg at birth were twice as likely to develop the autoimmune disease as those who weighed between the average of 3.2 to 3.85 kg at birth.

The results held true even after taking account of factors likely to influence the baby's birthweight.

These included socioeconomic status, parental smoking, maternal diabetes, age at first period, use of oral contraceptives or HRT, breastfeeding and weight.

There is no obvious biological explanation for the findings, say the authors. But adults with rheumatoid arthritis have abnormal hormone regulation, and it is thought that this process may be triggered while in the womb.

Although completely speculative, they go on to suggest that if the risk of rheumatoid arthritis could be lessened during pregnancy, altering the mother's diet could open up an exciting avenue for prevention.


'/>"/>

Contact: Rachael Davies
rdavies@bma.org.uk
44-020-738-36529
BMJ-British Medical Journal
Source:Eurekalert

Page: 1

Related medicine news :

1. AARP: Under Heavy Economic Pressure, Hispanics 45+ Look To Workplace, Families
2. Preference for alcohol in adolescence may lead to heavy drinking
3. Alzheimers Starts Earlier for Heavy Drinkers, Smokers
4. Its Spring Break: How Much Does Heavy Drinking Affect Your Body?
5. Elbow, Shoulder Injuries Take Heavy Toll on Pro Baseball Players
6. New sensor system improves detection of lead, heavy metals
7. Heavy marijuana use linked to gum disease
8. Heavy metal slips down UK air quality charts
9. Cardiovascular disease death rates decline, but risk factors still exact heavy toll
10. Heavy traffic makes breathing a burden in children
11. Heavy drinking, conduct disorder linked to high-risk sexual behavior
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2017)... ... September 23, 2017 , ... Silicon Valley Hair Institute, the leading ... new blog post focused on the ARTAS® hair transplant system and the younger demographic. ... the latest, most technologically sophisticated methods of hair restoration. , “It can be emotionally ...
(Date:9/22/2017)... Plano, TX (PRWEB) , ... September 22, 2017 , ... ... created to strengthen the communities they serve as part of the nationally recognized ‘Agents ... by working closely with nonprofit organizations and community leaders to seek out those who ...
(Date:9/22/2017)... ... 22, 2017 , ... Happy Living’s mission - to improve the health and ... the entertaining and delicious worlds of theatre and wines. , After watching Scott ... to turn his play into a book. The Greener The Grass ( https://www.happyliving.com/books/the-greener-the-grass ) ...
(Date:9/22/2017)... (PRWEB) , ... September 22, 2017 , ... ... host Rob Lowe, explores the world of Alzheimer’s. Alzheimer’s is a disease estimated ... disease. This according to information published by the Alzheimer’s Association, a leading voice ...
(Date:9/22/2017)... ... September 22, 2017 , ... Egg freezing and embryo freezing ... have a slight statistical advantage for live births, frozen eggs offer many advantages, ... women undergoing medical treatment or who are concerned about the decline of their ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... YORK , Sept. 12, 2017   EcoVadis , the leading ... has published the first annual edition of its Global CSR Risk and ... companies evaluated by EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 ... ... Index ...
(Date:9/9/2017)... -- Eli Lilly and Company (NYSE: LLY ) ... lasmiditan, an investigational, oral, first-in-class molecule for the acute ... to placebo in the Phase 3 SPARTAN study. Detailed ... of the International Headache Society (IHC) in ... demonstrate lasmiditan,s potential to reduce pain and provide freedom ...
(Date:9/7/2017)... , Sept. 7, 2017  Zimmer Biomet Holdings, Inc. ... healthcare, today announced that it will be participating in ... Conference at the Grand Hyatt hotel in New York.  ... at 11:40 a.m. Eastern Time. A live ... Biomet,s Investor Relations website at http://investor.zimmerbiomet.com .   ...
Breaking Medicine Technology: