Navigation Links
Heavy Drinking Linked to Aggressive Prostate Cancer
Date:7/13/2009

Consumption also appears to undercut effect of cancer-prevention drug,,

MONDAY, July 13 (HealthDay News) -- Heavy drinking, especially when it's beer, increases the risk for highly aggressive prostate cancer, a new study finds.

The researchers did not set out to determine the effect of alcohol consumption on prostate cancer risk but rather to test the effectiveness of finasteride (Proscar, Propecia), a drug prescribed to prevent prostate cancer.

And they found that heavy drinking reduces the cancer-preventing effect of finasteride. But the researchers did not stop there.

"Within the data in that trial, we could address a large number of questions," said Alan R. Kristal, associate head of the cancer prevention program at the Fred Hutchinson Cancer Research Center and an author of a report on the study published online July 13 in Cancer.

One question was the possible relationship between alcohol consumption and prostate cancer risk. The study, which included more than 10,000 men, found that those who drank heavily -- 50 grams (1.7 ounces) of pure alcohol a day, the amount in four shots of hard liquor, five or more days a week -- were more than twice as likely as less heavy drinkers to develop what is called high-grade prostate cancer. There was no difference in prostate cancer risk between nondrinkers and those who drank moderately.

"The majority of [prostate] cancers are low-grade," explained Kristal, who is also a professor of epidemiology at the University of Washington. "They grow very slowly, and 100 percent of men with it live for 10 years. Most men die of something else. With high-grade prostate cancer, survival at 10 years is only 60 to 70 percent."

Most heavy drinkers in the study drank beer, Kristal said. "They are six-pack-a-day drinkers," he said. "But there is no logical reason to think there is anything special about beer that increases the risk that does not apply to other forms of alcohol."

True, said Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society. The number of men in the study was too small to establish a relationship between prostate cancer and overall alcohol consumption, he said, but the finding might be enough to put prostate cancer on the list of malignancies that are affected by alcohol intake.

"Certain cancers are commonly associated with alcohol -- head and neck cancer, esophageal cancer, breast cancer," Lichtenfeld said. "Similar consistent information in regard to prostate cancer and alcohol really doesn't exist. But this was a well-defined and carefully developed study, an excellent opportunity to help answer that question."

The study provides "what is probably the best information we have on the possible relationship," Lichtenfeld said. "And one of the take-away messages we have is that drinking a lot of alcohol is a risk factor for developing aggressive prostate cancer."

It's not possible, Lichtenfeld said, to say anything about heavy drinking of wine and hard liquor because of the small number of such drinkers in the study. But people who drink equivalent amounts of alcohol in wine or hard liquor should not take comfort from that lack of statistical significance, he said.

"To reduce the risk of prostate cancer, it is best for you to reduce your intake of large amounts of alcohol," he said.

More information

The American Cancer Society has more on the established risk factors for prostate cancer.



SOURCES: Alan R. Kristal, D.P.H., associate head, cancer prevention program, Fred Hutchinson Cancer Research Center, Seattle, and professor, epidemiology, University of Washington, Seattle; Len Lichtenfeld, M.D., deputy chief medical officer, American Cancer Society, Atlanta; July 13, 2009, Cancer, online


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Summer Travel Destinations are Heavy on Fun - and Sun
2. US Navy culture and workplace leads to heavy drinking
3. Heavy Periods May Be Due to a Clotting Disorder
4. Years of Heavy Smoking Raises Heart Risks
5. Grapefruit-Heavy Diet Helped Spur Dangerous Clot
6. Xanodynes New Drug Application for the Treatment of Heavy Menstrual Bleeding (Menorrhagia) Accepted for Filing with a Priority Review Classification
7. Obesity Just as Risky for Teens as Heavy Smoking
8. Heavy marijuana use may damage developing brain in teens, young adults
9. Wake Up to the Health Risks of Heavy Snoring
10. Heavy Smoking as Teenager Might Add Pounds Later
11. Mayo researchers offer new insight into effectiveness of procedure to stop heavy menstrual bleeding
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Heavy Drinking Linked to Aggressive Prostate Cancer
(Date:10/13/2017)... EDWARDSVILLE, Ill. (PRWEB) , ... ... ... University Edwardsville School of Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and ... educated healthcare professionals on guideline updates for the primary prevention of cardiovascular ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for ... for action towards gender equality at their inaugural Summit in New York City in ... reached a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the ... save lost souls in the Philippines. “The Journey: From the Mountains to the Mission ... of the Bible. She has taught all ages and currently teaches a class of ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company ... of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every ... meet the highest standard. , These products are also: Gluten Free, Non-GMO, ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... Hair Restoration, has recently contributed a medical article to the newly revamped ... Dr. Mohebi’s article spotlights the hair transplant procedure known as Follicular Unit ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... and NEW YORK , Sept. 27, 2017 ... mobile health and big data solutions, today announced that its MyDario product ... check your local TV listings for when The Dr. Oz Show airs ... The ... this month. ...
(Date:9/22/2017)... -- As the latest Obamacare repeal effort moves is debated, ... and Lindsey Graham (R-SC) medical device market ... is in an odd place.  The industry wants repeal ... on medical device sales passed along with the Affordable ... visits and hospital customers with the funding to invest ...
(Date:9/18/2017)... KALAMAZOO, Mich. , Sept. 18, 2017 ... , and OptiMed Specialty Pharmacy of Kalamazoo, ... offer a strategic hub service that expedites and streamlines ... personal spirometer, Spiro PD 2.0, and wellness management services.  ... is a medical device used to measure lung function ...
Breaking Medicine Technology: