Navigation Links
Heat Therapy May Help Prevent Esophageal Cancer
Date:5/27/2009

Barrett's esophagus patients benefit from destruction of abnormal cells, study shows

WEDNESDAY, May 27 (HealthDay News) -- Radiofrequency ablation is an effective treatment for precancerous Barrett's esophagus, researchers have found.

In people with Barrett's esophagus, repeated acid reflux causes cells that line the esophagus to be replaced by cells similar to those found in the intestine, according to background information provided in a news release. A small number of people with Barrett's esophagus develop a deadly form of cancer called esophageal adenocarcinoma.

The new study included 127 people randomly selected to receive either radiofrequency ablation (RFA) -- which uses heat to destroy abnormal cells -- or a "sham" version of the procedure, to assess the effect on dysplasia, a more advanced stage of Barrett's esophagus in which the abnormal cells acquire precancerous traits.

Among patients with low-grade dysplasia, 90.5 percent of those who received RFA were dysplasia-free 12 months after treatment, compared with 22.7 percent of those in the sham therapy group. Of those with high-grade dysplasia, 81 percent had complete eradication of abnormal cells, compared with 19 percent of those in the sham treatment group, the researchers found.

Overall, 77.4 percent of patients treated with RFA had complete eradication of abnormal cells, compared with 2.3 percent of the sham treatment group. The study also found that 3.6 percent of those in the RFA group and 16.3 percent of those in the sham group had progression towards disease, while 1.2 percent of RFA patients and 9.3 percent of sham patients developed esophageal adenocarcinoma.

"These results show there is a substantial difference between treatment with radiofrequency ablation and a placebo or 'sham' treatment. It's a strongly positive finding," principal investigator Dr. Nicholas Shaheen, director of the Center for Esophageal Diseases and Swallowing at the University of North Carolina at Chapel Hill, said in the news release.

The study, published in the May 28 issue of the New England Journal of Medicine, received funding from the company that makes the radiofrequency ablation unit used in the study.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about Barrett's esophagus.



-- Robert Preidt



SOURCE: University of North Carolina at Chapel Hill, news release, May 27, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New therapy enlists immune system to boost cure rate in a childhood cancer
2. Worlds First Animatronic Animal Therapy Program Set to Open
3. What You Need to Know in Your 40s to Have a Healthy Menopause -- Without Hormone Replacement Therapy
4. Heart Rhythm Society Introduced to New Method for Optimizing Cardiac Resynchronization Therapy During Exercise
5. CORRECTION: Viral Genetics Pursues Promising New Therapy for Lyme Disease With Grant from Time for Lyme, Inc.
6. Pills Plus Psychotherapy Can Beat Insomnia
7. Study Shows NeuroStar TMS Therapy(R) Improved Key Elements of Cognition in Patients with Major Depressive Disorder
8. MEDai Helps Medicare Part D Sponsors Adhere to CMS Medication Therapy Management Initiative
9. Theravive.com Expands Values Counseling and Therapy Into Michigan, Florida, and Washington State
10. Rexin-G Controls Tumor Growth and Improves Survival in Chemotherapy-Resistant Sarcoma and Osteosarcoma: Phase I/II and Phase II Studies, ASCO 2009
11. Light Sciences Oncology Announces Results of Study on Immunotherapeutic Mechanism of Aptocine(TM), a Novel Light-Activated Drug Therapy for Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Heat Therapy May Help Prevent Esophageal Cancer
(Date:6/27/2016)... , ... June 27, 2016 , ... ... edge technology to revolutionize the emergency ambulance transport experience for the millions of ... of how Uber has disrupted the taxi industry through the use of technology. ...
(Date:6/26/2016)... Viejo, California (PRWEB) , ... June 26, 2016 , ... ... Final Cut Pro X. , "Film editors can give their videos a whole new ... said Christina Austin - CEO of Pixel Film Studios. , ProSlice Levels contains ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, ... work on several important health care topics including advance care planning, healthcare costs ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the largest ... as the Medical Director of its new Mesquite-Samuell Farm facility. , “We are ... Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical Systems ... "Company"), which develops, markets and sells medical devices and ... , signed a strategic cooperation agreement with Hongyuan Supply ... Supply Chain") on June 20, 2016, to develop Dehaier,s ... strategic cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s ...
(Date:6/24/2016)... Mass. , June 24, 2016   Pulmatrix, ... pharmaceutical company developing innovative inhaled drugs, announced today that ... Russell Investments reconstituted its comprehensive set of ... "This is an important milestone for Pulmatrix," ... will increase shareholder awareness of our progress in developing ...
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
Breaking Medicine Technology: