Navigation Links
Heat Therapy May Help Prevent Esophageal Cancer
Date:5/27/2009

Barrett's esophagus patients benefit from destruction of abnormal cells, study shows

WEDNESDAY, May 27 (HealthDay News) -- Radiofrequency ablation is an effective treatment for precancerous Barrett's esophagus, researchers have found.

In people with Barrett's esophagus, repeated acid reflux causes cells that line the esophagus to be replaced by cells similar to those found in the intestine, according to background information provided in a news release. A small number of people with Barrett's esophagus develop a deadly form of cancer called esophageal adenocarcinoma.

The new study included 127 people randomly selected to receive either radiofrequency ablation (RFA) -- which uses heat to destroy abnormal cells -- or a "sham" version of the procedure, to assess the effect on dysplasia, a more advanced stage of Barrett's esophagus in which the abnormal cells acquire precancerous traits.

Among patients with low-grade dysplasia, 90.5 percent of those who received RFA were dysplasia-free 12 months after treatment, compared with 22.7 percent of those in the sham therapy group. Of those with high-grade dysplasia, 81 percent had complete eradication of abnormal cells, compared with 19 percent of those in the sham treatment group, the researchers found.

Overall, 77.4 percent of patients treated with RFA had complete eradication of abnormal cells, compared with 2.3 percent of the sham treatment group. The study also found that 3.6 percent of those in the RFA group and 16.3 percent of those in the sham group had progression towards disease, while 1.2 percent of RFA patients and 9.3 percent of sham patients developed esophageal adenocarcinoma.

"These results show there is a substantial difference between treatment with radiofrequency ablation and a placebo or 'sham' treatment. It's a strongly positive finding," principal investigator Dr. Nicholas Shaheen, director of the Center for Esophageal Diseases and Swallowing at the University of North Carolina at Chapel Hill, said in the news release.

The study, published in the May 28 issue of the New England Journal of Medicine, received funding from the company that makes the radiofrequency ablation unit used in the study.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about Barrett's esophagus.



-- Robert Preidt



SOURCE: University of North Carolina at Chapel Hill, news release, May 27, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New therapy enlists immune system to boost cure rate in a childhood cancer
2. Worlds First Animatronic Animal Therapy Program Set to Open
3. What You Need to Know in Your 40s to Have a Healthy Menopause -- Without Hormone Replacement Therapy
4. Heart Rhythm Society Introduced to New Method for Optimizing Cardiac Resynchronization Therapy During Exercise
5. CORRECTION: Viral Genetics Pursues Promising New Therapy for Lyme Disease With Grant from Time for Lyme, Inc.
6. Pills Plus Psychotherapy Can Beat Insomnia
7. Study Shows NeuroStar TMS Therapy(R) Improved Key Elements of Cognition in Patients with Major Depressive Disorder
8. MEDai Helps Medicare Part D Sponsors Adhere to CMS Medication Therapy Management Initiative
9. Theravive.com Expands Values Counseling and Therapy Into Michigan, Florida, and Washington State
10. Rexin-G Controls Tumor Growth and Improves Survival in Chemotherapy-Resistant Sarcoma and Osteosarcoma: Phase I/II and Phase II Studies, ASCO 2009
11. Light Sciences Oncology Announces Results of Study on Immunotherapeutic Mechanism of Aptocine(TM), a Novel Light-Activated Drug Therapy for Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Heat Therapy May Help Prevent Esophageal Cancer
(Date:12/2/2016)... Milford, NJ (PRWEB) , ... December 02, 2016 , ... ... Nothing Water has some unique properties including its unmatched natural purity of just 6 ... as clean and crisp. , Nothing Water has been available in several ShopRite and ...
(Date:12/2/2016)... ... December 02, 2016 , ... Clarify Health ... has raised $6.0 million in an initial round of funding. The round was ... and their caregivers can receive far better care through the application of the ...
(Date:12/2/2016)... ... December 02, 2016 , ... ‘Tis the season for giving! Today, 20 ... the National Family Partnership and the Drug Enforcement Administration as part of the National ... the 10 winning schools who decorated their campuses with this year’s Red Ribbon Week ...
(Date:11/30/2016)... PALMYRA, Wisconsin (PRWEB) , ... November 30, 2016 ... ... inclusion in the 2016 Deloitte Wisconsin 75, an annual ranking and recognition of ... consecutive year on the list, having ranked from 2008-2016. In addition, Standard Process ...
(Date:11/30/2016)... ... November 30, 2016 , ... ... and stylish design wanted by today’s consumers at an affordable price, is now ... says the new watch is “a game changer” when it comes to the ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... in the ECG Cables And ECG Leadwires Market owing to ... devices. On the other hand, the Asia-Pacific ... rate during the forecast period. The market players ... plc ( Ireland ), Koninklijke Philips N.V. ( ... ( China ), held major share of the ...
(Date:12/2/2016)... PUNE, India , December 2, 2016 /PRNewswire/ ... research report "In Vitro Diagnostics/IVD Market by Product ... Diagnostics, Hematology), Application (Diabetes, Oncology, Cardiology, Nephrology, Infectious ... the global market is valued at USD 60.22 ... grow at a CAGR of 5.5% during the ...
(Date:12/2/2016)... On Thursday, December 1st 2016, ... research, development and innovation in the biopharmaceutical industry at ... in the presence of Sergey Tsyb, Vice Minister of ... , Natalia Sanina, First Vice Chairman of the ... of Roszdravnadzor, National Service of Control in Healthcare, Sergey ...
Breaking Medicine Technology: