Navigation Links
Heart may hold key to unexplained nausea in youths
Date:8/25/2011

WINSTON-SALEM, N.C. Aug. 24, 2011 -- Heart rate and blood pressure regulation may hold the key to treating unexplained chronic nausea in children. In a new study by researchers at Wake Forest Baptist Medical Center, a drug commonly used to treat a condition known as orthostatic intolerance (OI), which causes dizziness and occasional fainting when patients stand for long periods, was shown to reduce debilitating chronic nausea in patients.

"There seems to be a connection between heart rate and blood pressure, and chronic nausea," said John Fortunato, M.D., assistant professor of pediatrics at Wake Forest Baptist and lead author of the study. "When we treated the heart rate issues, the nausea was reduced."

Unexplained chronic nausea affects up to 25 percent of children in the United States and can be a debilitating disorder. Because the condition is poorly understood, treatments have not been very effective and have typically focused on alleviating the gastroenterology symptoms.

The retrospective study published in the August issue of Clinical Autonomic Research, involved 17 patients, ages 11 to 17 years, who had suffered from unexplained nausea and dizziness for a year and had OI.

Study participants were treated with fludrocortisone for four weeks. Fludrocortisone is a drug used in OI patients to diminish the exaggerated increase in heart rate and drop in blood pressure that occurs when standing. Sixty-five percent (11 out of 17) of the patients in this study experienced at least 50 percent or greater improvement in nausea after treatment with fludrocortisone, the same drug used to treat their OI.

"We may now have a more directed way to treat this condition," Fortunato said. "This is proof of concept research and gives us a real possibility for a new treatment."

Based on this study, Fortunato hopes to conduct a larger clinical trial to determine the possibility of this drug's use, as well as other potential drugs, as management tools for children with unexplained chronic nausea and OI.


'/>"/>

Contact: Marguerite Beck
marbeck@wakehealth.edu
336-716-2415
Wake Forest Baptist Medical Center
Source:Eurekalert

Related medicine news :

1. Antidepressant Tied to Dangerous Heart Rhythm: FDA
2. Antidepressant Tied to Dangerous Heart Rhythm, FDA Says
3. Common Heart Dysfunction Can Help Bring on Heart Failure
4. Women With Heart Failure Treated as Well as Men: Study
5. Injectable Psoriasis Drugs May Not Hike Heart Risks: Study
6. Most Heart Attack Patients Who Need Angioplasty Quickly Get It: Study
7. Infections Among Those With Heart Devices Has Doubled: Study
8. Steps Outlined to Screen All Newborns for Heart Defects
9. Marriage May Do a Heart Good for Bypass Surgery
10. Newest screen for newborns will indicate heart problems
11. Imaging probe allows noninvasive detection of dangerous heart-valve infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... KS (PRWEB) , ... February ... ... StaffBridge sets a new technology standard in staffing, scheduling, and reporting for ... monitor, and predict activity throughout the entire staffing process. StaffBridge technology improves ...
(Date:2/26/2017)... , ... February 26, 2017 , ... ... after receiving cognitive rehabilitation, according to a study released today at the 1st ... cognitive rehabilitation programs are proven to be effective in improving cognitive function in ...
(Date:2/25/2017)... ... February 25, 2017 , ... FCPX users now have the ability ... Film Studios. With ProSharpen Color users have total control over sharpening amount, sharpening radius, ... range. With color spectrum tools users can visually see the color range effected with ...
(Date:2/24/2017)... ... February 24, 2017 , ... Houston ... options at his office, Antoine Dental Center. Currently, patients can get single dental ... may apply, but patients can learn more about these offers by contacting Antoine ...
(Date:2/24/2017)... , ... February 24, 2017 , ... ... business development, education, networking and recognition opportunities as well as advocacy for the ... in Holmdel, NJ on February 23. The Council's Innovation Forecast event highlights ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... STOCKHOLM , Feb 27, 2017 Period October – ... Operating result amounted to SEK -16.4 (-6.4) million ... -0.27 per share (-0.22) before and after dilution Cash flow ... ... amounted to SEK 0.4 (0.4) million Operating result amounted to ...
(Date:2/24/2017)... -- Research and Markets has announced the addition of ... Forecast to 2025" report to their offering. ... The Global Wireless Health Market ... the next decade to reach approximately $330.5 billion by 2025. ... all the given segments on global as well as regional levels ...
(Date:2/24/2017)... and Markets has announced the addition of the "Dry eye Drugs ... ... Drugs Price Analysis and Strategies - 2016, provides drug pricing data and ... following questions: What are the key drugs ... in the Global Dry eye market? What are the ...
Breaking Medicine Technology: