Navigation Links
Heart may hold key to unexplained nausea in youths
Date:8/25/2011

WINSTON-SALEM, N.C. Aug. 24, 2011 -- Heart rate and blood pressure regulation may hold the key to treating unexplained chronic nausea in children. In a new study by researchers at Wake Forest Baptist Medical Center, a drug commonly used to treat a condition known as orthostatic intolerance (OI), which causes dizziness and occasional fainting when patients stand for long periods, was shown to reduce debilitating chronic nausea in patients.

"There seems to be a connection between heart rate and blood pressure, and chronic nausea," said John Fortunato, M.D., assistant professor of pediatrics at Wake Forest Baptist and lead author of the study. "When we treated the heart rate issues, the nausea was reduced."

Unexplained chronic nausea affects up to 25 percent of children in the United States and can be a debilitating disorder. Because the condition is poorly understood, treatments have not been very effective and have typically focused on alleviating the gastroenterology symptoms.

The retrospective study published in the August issue of Clinical Autonomic Research, involved 17 patients, ages 11 to 17 years, who had suffered from unexplained nausea and dizziness for a year and had OI.

Study participants were treated with fludrocortisone for four weeks. Fludrocortisone is a drug used in OI patients to diminish the exaggerated increase in heart rate and drop in blood pressure that occurs when standing. Sixty-five percent (11 out of 17) of the patients in this study experienced at least 50 percent or greater improvement in nausea after treatment with fludrocortisone, the same drug used to treat their OI.

"We may now have a more directed way to treat this condition," Fortunato said. "This is proof of concept research and gives us a real possibility for a new treatment."

Based on this study, Fortunato hopes to conduct a larger clinical trial to determine the possibility of this drug's use, as well as other potential drugs, as management tools for children with unexplained chronic nausea and OI.


'/>"/>

Contact: Marguerite Beck
marbeck@wakehealth.edu
336-716-2415
Wake Forest Baptist Medical Center
Source:Eurekalert

Related medicine news :

1. Antidepressant Tied to Dangerous Heart Rhythm: FDA
2. Antidepressant Tied to Dangerous Heart Rhythm, FDA Says
3. Common Heart Dysfunction Can Help Bring on Heart Failure
4. Women With Heart Failure Treated as Well as Men: Study
5. Injectable Psoriasis Drugs May Not Hike Heart Risks: Study
6. Most Heart Attack Patients Who Need Angioplasty Quickly Get It: Study
7. Infections Among Those With Heart Devices Has Doubled: Study
8. Steps Outlined to Screen All Newborns for Heart Defects
9. Marriage May Do a Heart Good for Bypass Surgery
10. Newest screen for newborns will indicate heart problems
11. Imaging probe allows noninvasive detection of dangerous heart-valve infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... FL (PRWEB) , ... April 30, 2016 , ... ... and engineer of patented products, announces the Pick Up Springboard, an automotive invention ... and Light Truck Manufacturing industry is worth $162 billion," says Scott Cooper, CEO ...
(Date:4/29/2016)... ... April 29, 2016 , ... Since launching its ... charitable foundation serving the footwear industry, has broken all previous participation records in ... companies across 23 states during the months of April and May, the 2016 ...
(Date:4/29/2016)... Calif. (PRWEB) , ... April 29, 2016 , ... Our ... An effective way to confront and deal with these stressors is to adopt a ... to be good for you. Risa Groux, a certified Holistic Nutritionist and the creator ...
(Date:4/29/2016)... CA (PRWEB) , ... April 29, 2016 , ... ... advocating optimistic healthcare awareness and author of best seller "LOVE, MEDICINE and MIRACLES") ... Radio Monday, May 2, 2016 and podcasted thereafter . Dr. Bernie Siegel, ...
(Date:4/29/2016)... ... April 29, 2016 , ... Coast Dental Fort Stewart is celebrating its grand ... in the Exchange Furniture Mall at 112 Vilseck Road in Fort Stewart. There will ... Plus attendees will have the opportunity to meet general dentists Thomas Richards, DDS, and ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... Glycotope GmbH, a clinical-stage immuno-oncology company built ... Dr. Alfredo Zurlo as Chief Medical Officer. ... years clinical experience and a proven track record in ... at Mologen AG where he was Chief Medical Officer ... held various positions at F Hoffmann La Roche and ...
(Date:4/28/2016)... , April 28, 2016  Marking its ... accessible breast and ovarian cancer risk test, ... analyzing 30 genes that highly impact the most ... Available today, the Color Test analyzes hereditary cancer ... stomach, and uterine cancers. The Color Test is ...
(Date:4/28/2016)... , April 28, 2016 Dr. ... and Ste phen ... ArisGlobal®, a leading provider of cloud-based software solutions for life sciences, ... team to bring a wealth of insight to a growing business. ... knowledge. George Phillips joined ArisGlobal in the ...
Breaking Medicine Technology: