Navigation Links
Heart failure risk model validated

Researchers at Emory University School of Medicine created the Health ABC Heart Failure Model for predicting risk of new onset heart failure in the elderly. Now that model has been strengthened by validating it in a separate library of patient data from an earlier cardiovascular study.

The results suggest the Health ABC risk model can be used to identify high-risk individuals for whom interventions can be targeted cost-effectively to prevent heart failure.

"This is a scoring system that could help individuals or their physicians understand their five-year risk for heart failure, using basic risk factors that are easily obtained at relatively low cost," says Javed Butler, MD, MPH, associate professor of medicine and director of heart failure research at Emory University School of Medicine.

Andreas Kalogeropoulos, MD, a post-doctoral research fellow with Butler, presents the findings Monday at the American College of Cardiology conference in Orlando.

Heart failure is the leading cause of hospitalization in people older than 65 and greatly increases the risk of sudden cardiac arrest.

The Health ABC model uses nine clinical measures to estimate the risk of heart failure in patients who haven't necessarily been seen by doctors for coronary heart disease before. The nine measures are: age, history of coronary heart disease, smoking, blood pressure, heart rate, left ventricular hypertrophy measured by electrocardiography, and blood levels of glucose, creatinine and albumin.

Several individual risk factors for heart failure have been identified, but Butler says the model is the first that combines the risk factors into a system for predicting risk for any given individual. The model categorizes individuals into four risk categories ranging from less than 5 (low) to more than 20 percent (very high) 5-year risk, and has been shown to perform well for men, women, Caucasians and African Americans.

"Considering the high cost of care and poor outcomes for patients who develop heart failure, any effort to identify these individuals early on and facilitate intervention is likely to be of significant benefit," Butler says.

The Health ABC model grew out of the Health Aging and Body Composition Study, which followed 2,935 elderly people in the Pittsburgh and Memphis areas over seven years starting in 1998. The model was validated by assessing it in 5,335 people without pre-existing heart failure from North Carolina, California, Maryland and Pennsylvania who were participants in the Cardiovascular Health Study beginning in 1989.

Butler and his colleagues also are presenting data from the Health ABC study confirming previous work elsewhere showing that blood glucose can predict heart failure risk even in non-diabetics and evaluating the additional information doctors can glean from different measures of blood pressure.

Reference for the Health ABC heart failure risk model: Circulation Heart Failure 2008,1:125-133


Contact: Sarah Goodwin
Emory University

Related medicine news :

1. Drug for cluster headaches may cause heart problems
2. Use of certain lipid measures not more effective in predicting coronary heart disease
3. Restricting Blood Flow May Help Heart Bypass Patients
4. Urban Smog Tough on Young Adults Hearts
5. Stanford study highlights cost-effective method of lowering heart disease risks
6. Vitamin Es lack of heart benefit linked to dosage
7. Drug That Lowers Resting Heart Rate Being Tested
8. Heart Attack Boosts Diabetes Risk
9. Embryonic Stem Cells Repair Human Heart
10. U of M study: Early treatment can reverse heart damage
11. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
Post Your Comments:
(Date:11/30/2015)... ... 30, 2015 , ... An inventor from Charlottesville, Va., is concerned about the ... had high blood pressure due to loud noises," she said, "so I decided that ... pollution as well as radio waves and microwaves." , The baby BABY MUFF prevents ...
(Date:11/30/2015)... ... November 30, 2015 , ... In an interview with Andy Mitchell of Peconic ... on Long Island’s east end. During the broadcast, entitled “Eyes: the Window to the ... glaucoma and cataracts, and how a visit with his grandmother to her physician put ...
(Date:11/30/2015)... ... November 30, 2015 , ... Since its inception, Seniors ... independent living, assisted living and all other retirement options. Support for issues surrounding ... research remains a top priority. , So it’s no surprise that every ...
(Date:11/30/2015)... ... November 30, 2015 , ... Holcomb – Kreithen Plastic ... surgery practices in Florida, is proud to announce that Dr. Joshua Kreithen, one ... Ethicon Inc., a Johnson & Johnson Company. , Ethicon is a global medical ...
(Date:11/30/2015)... ... November 30, 2015 , ... Sikka Software announced today that they are showcasing ... dentists to make complex business decisions by providing the tools and information they need ... survey with 10 procedures customized by zip code. , The Sikka Software Ecosystem ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... , Nov. 30, 2015   Nuance Communications, Inc. ... National Decision Support Company (NDSC) today jointly announced ... collaboration capabilities that utilize the American College of Radiology,s ... provider organizations to comply with current and emerging ... --> By combining clinical decision support, ...
(Date:11/30/2015)... Booth #4303 – The Imaging Components business of ... broader array of products in a new booth (#4303) at ... North America in Chicago ... X-ray components "At the Heart of Imaging." Products will include ... Varian,s Claymount brand, and computer-aided diagnostic software from MeVis as ...
(Date:11/30/2015)... 30, 2015  Hanger, Inc. (NYSE: HGR ) ... the terms of its previously announced consent solicitation (as ... $200,000,000 aggregate principal amount 7⅛% Senior Notes due 2018 ... consent fees payable pursuant to the Consent Solicitation, (ii) ... (iii) the expiration date of the Consent Solicitation.    ...
Breaking Medicine Technology: