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Heart failure hospitalization more than doubles in IBD flares
Date:5/18/2014

riod. Persistent activity was defined as repeated prescriptions or hospitalisations.

Dr Kristensen said: "We found that patients with new-onset IBD had a 37% increased risk of hospitalisation for heart failure during a mean follow-up of 6.4 years compared to the healthy population. But the risk more than doubled during periods of IBD activity."

He added: "When IBD patients had flares their risk of hospitalisation for heart failure was 2.5 times greater, and it was 2.7 times greater during persistent activity. There was no increased risk during the quiescent stages of IBD. Our findings suggest that efficient IBD treatment aimed at reducing the length and number of disease activity episodes might lower the risk of heart failure."

Dr Kristensen continued: "We found an increased risk of hospitalisation for heart failure in IBD patients of all ages, not just older patients. Gastroenterologists and other health professionals need to be aware of the increased risk of cardiovascular diseases, including heart failure, in their daily handling of patients with IBD. It's also important that they don't neglect younger patients, who are also at cardiovascular risk."

IBD is known to have effects in the body beyond the intestine including anaemia, and musculoskeletal, dermatologic, hepatic and ocular complications. Dr Kristensen said: "Our results indicate that heart failure may need to be added to this list, and hence be considered when assessing these patients. Detecting heart failure early is crucial to halting its progression and improving prognosis."

Biological anti-inflammatory treatments offer the possibility of longer term remission to patients with IBD. Dr Kristensen said: "It will be interesting to see if these medications, which are increasingly used in IBD, lead to a reduction in the risk of heart failure and other cardiovascular diseases. We will investigate this question in a future observational study of all IBD patients i
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Contact: ESC Press Office
press@escardio.org
33-622-834-576
European Society of Cardiology
Source:Eurekalert

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