Navigation Links
Heart drug effective for treating symptom of muscular dystrophy
Date:5/4/2010

A medication most often used to treat heart arrhythmias also reduces a central symptom of myotonic dystrophy, the most common type of muscular dystrophy in adults.

The findings about the medication mexiletine a chemical cousin of lidocaine were published May 4 in the journal Neurology, a publication of the American Academy of Neurology.

Currently there is no drug approved to treat myotonic dystrophy, an inherited disease that is marked by progressive muscle weakness. While the course of the disease can vary dramatically from patient to patient, symptoms besides weakness can include muscle stiffness, difficulty speaking and swallowing, problems walking, and in some patients, heart problems and cataracts. Physicians estimate that approximately 40,000 Americans have the condition.

The researchers at the University of Rochester Medical Center found that mexiletine is effective at treating the myotonia muscle stiffness that is at the center of the disease. Turning a key in a lock, writing with a pen or pencil, picking up and setting down a pitcher of water all are formidable tasks for patients with myotonia. Sometimes the symptom first occurs when a patient shakes someone's hand, then cannot relax his or her grip for several seconds.

While several doctors have suspected that mexiletene helps relieve myotonia, this is the first placebo-controlled, double-blind study to show that it actually does so, said neurologist Richard Moxley III, M.D., an author of the study and an international expert on muscular dystrophy.

"It's important for physicians who treat patients to know that mexiletine is an option," said Moxley, who is director of the University's Neuromuscular Disease Center and professor of Neurology. "Several physicians who specialize in treating patients with myotonic dystrophy have found it to be effective for their patients, but we really wanted to study the issue closely. The medication really addresse
'/>"/>

Contact: Tom Rickey
tom_rickey@urmc.rochester.edu
585-275-7954
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New research identifies modifiable risk factors for heart disease
2. Magnetic field measurements of the human heart at room temperature
3. Summit Medical Group hosts “Go Red Day” to Raise Awareness of Heart Disease and Stroke
4. Top 10 Ways to Avoid a Heart Attack This Super Bowl
5. Blood Thinner Combos Risky for Heart Attack Patients
6. HeartMath Offers Free Certificates that Celebrate Love and the Heart
7. Texas Health Dallas Launches Screening Program for Female Heart Disease
8. NHLBI funds preclinical tests on devices for infants and children with congenital heart defects
9. Surgery on beating heart thanks to robotic helping hand
10. Renowned Cardiologist Offers Heart Healthy Tips for the Holiday Season
11. American Heart Month Recognized Feb. 1-28, 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... SC (PRWEB) September 02, 2014 The Wm. ... outreach fair and public town hall meeting for Veterans and ... available at the outreach fair to provide Veterans with valuable ... McMurry. “The town hall will provide a forum where we ... VA programs.” , The outreach fair will be held 4:45 ...
(Date:9/2/2014)... with lumpectomy followed by radiation therapy survived as ... to a large study conducted by researchers at ... Cancer Prevention Institute of California. , The comprehensive ... disease is the first to directly compare survival ... bilateral mastectomy (the removal of both breasts), unilateral ...
(Date:9/2/2014)... for their own spread throughout the body by coaxing ... according to a new report by Johns Hopkins scientists. ... Nature Communications , the researchers describe animal and cell-culture ... released by breast cancer cells. These molecules cause lymphatic ... to produce proteins called CCL5 and VEGF. CCL5 attracts ...
(Date:9/2/2014)... The Dream2Walk Foundation along with Gas Monkey Bar and ... Spinal Cord Injury Awareness Month featuring full band performances by ... Linear Automotive will be there hosting a Hot Rod, Rat ... 2pm. The car show is Pre 1964 only, with a ... concert. There will be trophies for top 3 and best ...
(Date:9/2/2014)... TUESDAY, Sept. 2, 2014 (HealthDay News) -- Two new ... One suggests that 6-year-olds who were breast-fed have a ... to bottle-fed infants, while the other finds a similar ... upholds the "many benefits of breast-feeding in the immediate ... Lenox Hill Hospital in New York City. She was ...
Breaking Medicine News(10 mins):Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 2Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 3Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 4Health News:‘Prepped’ by tumor cells, lymphatic cells encourage breast cancer cells to spread 2Health News:Gas Monkey Hosts Concert in Dallas Benefiting Dream2Walk Foundation with Linear Automotive 2Health News:More Evidence Breast-Feeding Lowers Child's Risk of Infections, Allergies 2
... HOUSTON - A genetic mutation that drives the initiation ... tumor growth and progression, scientists report in the journal ... the Kras oncogene opens up a new category of ... proved difficult to attack directly, said study co-lead author ...
... THURSDAY, April 26 (HealthDay News) -- Dogs who accidentally eat ... emit a toxic gas that can sicken veterinary staff, ... for Disease Control and Prevention say such canine gas attacks ... and such incidents "might be underreported." All of the ...
... issue of the journal Neurology , researchers at ... a simple, unobtrusive wrist sensor could gauge the severity ... but without the ungainly scalp electrodes and electrical ... clinically useful data from epilepsy patients as they go ...
... from University Hospitals (UH) Case Medical Center and Case ... findings that mammography remains beneficial for women in their ... issue of American Journal of Roentgenology , women ... mammography were diagnosed at earlier stages with smaller tumors ...
... , WEDNESDAY, April 25 (HealthDay News) -- When patients ... risk goes up quickly, new research finds. That ... warfarin or a newer, more expensive drug, Xarelto (rivaroxaban). ... which the upper chambers of the heart quiver or ...
... , WEDNESDAY, April 25 (HealthDay News) -- Heroin ... this sensitivity does not subside over the course of ... Researchers from the University of California-Los Angeles sought ... hyperalgesia) might change as a heroin addict moves from ...
Cached Medicine News:Health News:Mutant Kras drives pancreatic cancer maintenance via metabolic pathways 2Health News:Mutant Kras drives pancreatic cancer maintenance via metabolic pathways 3Health News:Mutant Kras drives pancreatic cancer maintenance via metabolic pathways 4Health News:Toxic Gas in Dogs' Vomit a Threat to Vets: CDC 2Health News:Gauging seizures' severity 2Health News:Gauging seizures' severity 3Health News:Study finds mammography beneficial for younger women 2Health News:Stopping Blood Thinners Raises Stroke Risk for Patients With Irregular Heartbeat 2
(Date:9/2/2014)... 2014 Reportbuyer.com has added a new ... Technologies for Molecular Imaging Devices ... The objectives of this study are to ... used for diagnostic purposes, present global market measurements ... market segments as well as forecast market and ...
(Date:9/2/2014)... , Sept. 2, 2014 Reportlinker.com ... available in its catalogue: Asia-Pacific ... http://www.reportlinker.com/p02353210/Asia-Pacific-Infusion-Therapy-Device-Market.html Abstract: The ... therapy devices included volumetric infusion pumps, syringe infusion ... connectors and stopcocks. These categories are segmented based ...
(Date:9/2/2014)... 2, 2014 The Pharmaceutical Care Management Association ... (PBMs), today filed a lawsuit in Iowa ... Iowa law that restricts tools used ... state,s employers and consumers.  The law—HF ... restricting the use of Maximum Allowable Cost (MAC) lists ...
Breaking Medicine Technology:Global Markets and Technologies for Molecular Imaging Devices 2Global Markets and Technologies for Molecular Imaging Devices 3Global Markets and Technologies for Molecular Imaging Devices 4Global Markets and Technologies for Molecular Imaging Devices 5Global Markets and Technologies for Molecular Imaging Devices 6Global Markets and Technologies for Molecular Imaging Devices 7Global Markets and Technologies for Molecular Imaging Devices 8Global Markets and Technologies for Molecular Imaging Devices 9Global Markets and Technologies for Molecular Imaging Devices 10Global Markets and Technologies for Molecular Imaging Devices 11Global Markets and Technologies for Molecular Imaging Devices 12Global Markets and Technologies for Molecular Imaging Devices 13Global Markets and Technologies for Molecular Imaging Devices 14Global Markets and Technologies for Molecular Imaging Devices 15Global Markets and Technologies for Molecular Imaging Devices 16Global Markets and Technologies for Molecular Imaging Devices 17Global Markets and Technologies for Molecular Imaging Devices 18Global Markets and Technologies for Molecular Imaging Devices 19Global Markets and Technologies for Molecular Imaging Devices 20Global Markets and Technologies for Molecular Imaging Devices 21Global Markets and Technologies for Molecular Imaging Devices 22Global Markets and Technologies for Molecular Imaging Devices 23Global Markets and Technologies for Molecular Imaging Devices 24Global Markets and Technologies for Molecular Imaging Devices 25Asia-Pacific Infusion Therapy Device Market 2Asia-Pacific Infusion Therapy Device Market 3Asia-Pacific Infusion Therapy Device Market 4Asia-Pacific Infusion Therapy Device Market 5Asia-Pacific Infusion Therapy Device Market 6Asia-Pacific Infusion Therapy Device Market 7Asia-Pacific Infusion Therapy Device Market 8Asia-Pacific Infusion Therapy Device Market 9Asia-Pacific Infusion Therapy Device Market 10Asia-Pacific Infusion Therapy Device Market 11Asia-Pacific Infusion Therapy Device Market 12
... ZURICH, December 9, 2011 NHS National ... ALFApump System Sequana Medical announced today the ... System commissioned by the National Innovation Centre, the NHS ... up the development and use of innovations that will ...
... ATLANTA, Dec. 8, 2011 CardioMEMS announced today that ... Devices advisory panel voted against the Champion Heart Failure ... allows cardiologists to monitor heart failure patients from their ... is safe with a vote of 9-1, the majority ...
Cached Medicine Technology:NHS National Innovation Centre Estimates Sequana Medical's ALFApump® System Could Save the NHS £50 Million in ascites Care Annually 2FDA Advisory Panel Recommends Against Approval of Champion® Heart Failure Management System for Patients With Heart Failure 2FDA Advisory Panel Recommends Against Approval of Champion® Heart Failure Management System for Patients With Heart Failure 3
... the PROTG® GPS™ Self-Expanding Nitinol ... delivered on a commitment to ... PROTG GPS Stents take that ... by adding tantalum markers at ...
Colloidal Gold Conjugated, Streptavidin - 12 OD...
Patent Pending lateral flow assay platform that contributes to increased sensitivty...
Gold Labeling kit for antibodies, the Coat-Block-Run Conjugation Kit pH 8-11; contains 1 bottle each of 20 nm and 40 nm Naked Gold...
Medicine Products: