Navigation Links
Heart disease risk appears associated with breast cancer radiation
Date:10/28/2013

Among patients with early stages of breast cancer, those whose hearts were more directly irradiated with radiation treatments on the left side in a facing-up position had higher risk of heart disease, according to research letter by David J. Brenner, Ph.D, D.Sc, of Columbia University Medical Center, New York, and colleagues.

Several reports have suggested links between breast cancer radiation and long-term cardiovascular-related deaths, according to the study background.

Researchers examined the radiation treatment plans of 48 patients with stage 0 through IIA breast cancer who were treated after 2005 at the New York University Department of Radiation Oncology. They calculated the association between radiation treatment factors, such as mean cardiac dose, cardiac risk, treatment side, body positioning and coronary events.

According to study results, the highest coronary risks were seen for left-sided treatment in women of high baseline risk treated in the supine (lying down, head facing up) position. The lowest risks were for right-sided treatment in low-baseline risk women. In left-sided radiation, prone (lying down, facing down) position reduces cardiac doses and risks, while body positioning has little effect in right-sided therapy (where the heart is always out of field).

"Because the effects of radiation exposure on cardiac disease seem to be multiplicative, the highest absolute radiation risks correspond to the highest baseline cardiac risk," the authors conclude. "Consequently, radiotherapy-induced risks of major coronary events are likely to be reduced in these patients by targeting baseline cardiac risk factors (cholesterol, smoking, hypertension), by lifestyle modification, and/or by pharmacological treatment."


'/>"/>

Contact: Karin Eskenazi
ket2116@cumc.columbia.edu
212-342-0508
The JAMA Network Journals
Source:Eurekalert

Page: 1

Related medicine news :

1. Pregnant women with hepatitis C may pass heartier viral strain to newborns, study suggests
2. Victory Healthcare Announces Heartburn Centers of Texas
3. Encouraging a healthy weight for a healthy heart
4. Rheumatoid arthritis and heart disease: Mayo Clinic studies shed light on dangerous connection
5. Congenital Heart Disease Global Clinical Trials Review, H2, 2013
6. Study shows no increased risk for heart attacks among HIV-positive patients with high CD4 cell count
7. AED.com Offers Recertified Philips HeartStart OnSite AED for $675
8. PharmaPoint: Chronic Heart Failure - US Drug Forecast and Market Analysis to 2022
9. Flu shot halves risk of heart attack or stroke in people with history of heart attack, study finds
10. Flu shot halves risk of heart attack or stroke in people with history of heart attack, study finds
11. AGH Cardiovascular Team Explores Implantable Device Designed to Treat Congestive Heart Failure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2016)... ... February 13, 2016 , ... ... Clinical Data Management Solution Providers list for its expertise in eClinical Solutions. DDi ... expertise to serve the technology needs of global clients. DDi provides smarter technology ...
(Date:2/12/2016)... LA (PRWEB) , ... February 12, 2016 , ... The ... St. Landry and Evangeline Parishes. The purpose of these scholarships is to encourage ... encourage those individuals to seek employment within these two parishes. , “We have ...
(Date:2/12/2016)... ... February 12, 2016 , ... CDRH Enforcement Trends: , Back to the Future , ... , As Winston Churchill said, “Those who don’t learn from history are doomed to ... expect when they come knocking this year. But that takes time. , Take a ...
(Date:2/12/2016)... ... February 12, 2016 , ... As a former television executive, ... demanding job, and no time to decompress, Rabinowitz found herself drawn to a casual ... for its impact on her life, implementing a 20-minute-per-day meditation practice with her team. ...
(Date:2/12/2016)... ... February 12, 2016 , ... The ... Zuckerberg San Francisco General Hospital on April 5-7. The series is a multi-day, ... new habits. The workshops cover a broad range of topics, including coaching skills, ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... Feb. 11, 2016 Laboratory glassware ... in laboratories. These may range from microscope slides to ... is made from borosilicate glass because of its low ... the other hand, started gaining popularity over the past ... to replace glass with plastic in several applications due ...
(Date:2/11/2016)... -- Governor Andrew M. Cuomo today announced a major expansion ... Western New York . This announcement, made ... includes a major expansion of Athenex,s North American headquarters ... , as well as the creation of a state-of-the-art, ... . The combined projects are expected to yield ...
(Date:2/11/2016)... 11, 2016  NOIT™ Research LLC, a private, leading-edge ... Change" campaign to assist needy families in obtaining one ... sold between February 10, 2016 and March 31, 2016, ... family. The NOIT is an auditory stimulus that plays ... language skills. Beth Shier , NOIT ...
Breaking Medicine Technology: