Navigation Links
Heart attacks are more serious if they occur at certain times of the day
Date:4/27/2011

People who have a heart attack are likely to be more seriously affected if the attack happens in the morning, reveals research published ahead of print in Heart journal.

Heart attacks that occur between 6am and noon are more likely to leave a 20% larger area of dead tissue (infarct) caused by the attack, which is more serious for the person affected, than at any other time of the day.

It is well established that a person's 24 hour body clock influences several cardiovascular physiological processes including the incidence of heart attacks, which tend to happen more around the time when a person is waking up from sleep, but what is less known is the extent of damage that this leads to.

Researchers in Madrid, Spain set out to determine the impact of time of day of a heart attack on the size of the dead tissue (infarct) caused in patients with an ST segment elevation myocardial infarction (STEMI) a type of heart attack caused by a prolonged period of blocked blood supply.

They analysed data on 811 patients with a STEMI heart attack admitted to the coronary care unit of Hospital Clinico San Carlos in Madrid between 2003 and 2009. They calculated the size of infarct by looking at enzyme release in patients.

The time of STEMI onset was divided into four 6-hour time periods in phase with 24-hour body clock rhythms.

Patients with the largest infarct size were found to be those who had a heart attack in the dark to light transition period of 6am to noon. These patients were found to have around a 21% higher level of enzymes in this period (which indicated a larger infarct size) than patients who had their heart attack between 6pm and midnight.

The greatest number of patients (269) had their heart attack in the 6am to noon period, followed by 240 patients who had their attack between noon and 6pm, 161 during the 6pm to midnight period, and 141 between midnight and 6am.

They also found that patients with a STEMI that happened in the anterior wall of the heart were left with a larger size of infarct than patients whose heart attacks happened in other locations.

The authors conclude: "If confirmed, these results may have a significant impact on the interpretation of clinical trials of cardioprotective strategies in STEMI."


'/>"/>

Contact: Emma Dickinson
edickinson@bmjgroup.com
44-020-738-36529
BMJ-British Medical Journal
Source:Eurekalert

Related medicine news :

1. ICU Patients at Risk for Rare Heart Rhythm Problem
2. Cook With Love This Valentines Day With Heart-Smart Recipes
3. Study finds racial gaps continue in heart disease awareness
4. Highmark Foundation Awards $120,000 to the American Heart Association
5. Womens Heart Disease Awareness Still Lacking
6. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
7. Migraine Linked to Increased Heart Attack Risk
8. PERSONALABS Offers Discounted Healthy Heart Online Blood Tests in February
9. Compound shows promise against intractable heart failure
10. New American Heart Association Survey Finds Heart Disease and Stroke Patients Face Significant Barriers in Obtaining Quality, Affordable Care
11. Ex-President Clinton Undergoes Heart Procedure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... ... April 29, 2016 , ... Innovations with Ed Begley ... upcoming episode, airing third quarter 2016 via Discovery Channel. Dates and show times ... Dairy Products, located in Greenwood, Wisconsin applies product research and development and continuous ...
(Date:4/29/2016)... ... April 29, 2016 , ... Natren, Inc. recently sent representatives ... Petbiotics ™, as they fondly call them. As animal lovers, they were ... their non-profit organizations. Animal rescues across the nation face huge hurdles rescuing animals ...
(Date:4/29/2016)... ... 2016 , ... Intellitec Solutions will be a sponsor at ... the Broward County Convention Center. The event is a chance for finance professionals ... public facility management. Intellitec Solutions will highlight their customized accounting solutions designed for ...
(Date:4/29/2016)... (PRWEB) , ... April 29, 2016 , ... In its ... 1Heart Caregiver Services continues its successful franchise development and expansion as it welcomes Ferdie ... extensive managerial and administrative experience in his 32 years of working in various industries. ...
(Date:4/28/2016)... ... April 28, 2016 , ... Sanford Health’s work ... A group of researchers and leaders from Sanford Health were selected to participate ... Its Cultural Impact ” and receive the 2016 Pontifical Key Innovation Award at ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... April 27, 2016 Oasmia ... developer of a new generation of drugs within ... survival results for Paclical/Apealea in the Phase III ... with epithelial ovarian cancer. These preliminary results showed ... combination with carboplatin versus Taxol in combination with ...
(Date:4/27/2016)... 2016 At the Sachs CEO ... a Phase 2 clinical study of its lead drug ... cochlear implantation (CI) surgery. This large, placebo-controlled, double-blind, phase ... Germany and France . ... the time of surgery. "Despite advances in cochlear implant ...
(Date:4/26/2016)... 26, 2016 US demand for infection ... 4.9 percent annually to $27.6 billion in 2020.  ... to decrease rates of healthcare-associated infections (HAIs) will ... and services.  Although declining, the overall rate of ... levels set by the CDC.  Recent statistics indicate ...
Breaking Medicine Technology: