Navigation Links
Heart attack risk differs between men and women
Date:11/29/2011

CHICAGO Findings on coronary CT angiography (CTA), a noninvasive test to assess the coronary arteries for blockages, show different risk scenarios for men and women, according to a study presented today at the Radiological Society of North America (RSNA).

Coronary artery disease (CAD) is a narrowing of the blood vessels that supply blood and oxygen to the heart. It is caused by a build-up of fat and other substances that form plaque on vessel walls. According to the Centers for Disease Control and Prevention, heart disease is the leading cause of death for both men and women in the U.S.

Researchers at the Medical University of South Carolina analyzed the results of coronary CTA on 480 patients, mean age 55, with acute chest pain. Approximately 65 percent of the patients were women, and 35 percent were men. The possibility of acute coronary syndrome was ruled out for each of the patients.

Using coronary CTA, the researchers were able to determine the number of vessel segments with plaque, the severity of the blockage and the composition of the plaque.

"The latest CT scanners are able to produce images that allow us to determine whether the plaque is calcified, non-calcified or mixed," said John W. Nance Jr., M.D., currently a radiology resident at Johns Hopkins Hospital in Baltimore, Md.

By comparing the coronary CTA results with outcome data over a 12.8-month follow-up period, the researchers were able to correlate the extent, severity and type of plaque build-up with the occurrence of major adverse cardiac events, such as a heart attack or coronary bypass surgery. The statistical analysis tested all plaques combined (calcified, non-calcified and mixed) and each individual plaque type separately.

"We found that the risks for cardiovascular events associated with plaque were significantly different between women and men," Dr. Nance said.

Within the follow-up period, 70 of the patients experienced major adverse cardiac events, such as death, heart attack, unstable angina or revascularization. In total, 87 major adverse cardiac events occurred among the patients during the follow-up period.

When the outcome data were correlated with the CTA combined plaque findings, the results indicated that women with a large amount of plaque build-up and extensive atherosclerosis are at significantly greater cardiovascular risk than men.

Specifically, the risk for major adverse cardiac events was significantly higher in women than in men when extensive plaque of any kind was present or when more than four artery segments were narrowed.

"This research tells us that extensive coronary plaque is more worrisome in women than the equivalent amount in men," Dr. Nance said.

However, when analyzing risk factors associated with the presence of individual types of plaque, the risk for major adverse cardiac events was greater in men, compared to women, when their artery segments contained non-calcified plaque.

Dr. Nance said the new data suggested that the atherosclerotic process, or hardening of the arteries, is not necessarily linear and that more research is needed to better understand the disease.

"Our research confirms that coronary CTA provides excellent prognostic information that helps identify risk, but there are gender differences that need to be considered," Dr. Nance said.


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Related medicine news :

1. Heart Attack Severity May Depend on Time of Day
2. Lengthy Hospital Transfers May Hamper Heart Attack Care
3. Depression can lead to heart disease
4. Low-Cal Diet Cuts Fat Around Heart in Obese People: Study
5. Scientists identify key area that could sever communication between brain and heart in disease
6. Substance in cancer medicine could prevent heart attacks
7. Surgery May Boost Survival With Dangerous Heart Condition
8. How Much Salt Is Best for the Heart?
9. Physically Demanding Work Raises Heart Risk in Unfit Men: Study
10. Disparities in heart health to be addressed by national leaders at womens health summit
11. Severity of heart attack is dependent on the time of day
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... March 23, 2017 , ... ... firm serving the families and businesses of the Norwalk and Vermillion areas, ... Ohio Recovery Center (N.O.R.A.) is a nonprofit, community-based substance abuse prevention and ...
(Date:3/23/2017)... Yardley, PA (PRWEB) , ... March 23, 2017 ... ... received Patient Oriented Disease Management Accreditation from the NCQA. The accreditation covers StayWell’s ... programs. , Accredited status is granted to organizations that have excellent programs ...
(Date:3/23/2017)... ... , ... The TouchPoint Solution, home of Buzzies *, is boosting the ... , “Buzzies change the way we interact with stress and live our day-to-day lives,” ... date in December 2016, The TouchPoint Solution has sold more than $750,000 in product ...
(Date:3/23/2017)... ... March 23, 2017 , ... After raising more than $1.135 million ... most-funded travel pillow in crowdfunding history, has established a U.S. Headquarters in ... travel innovation to Americans. , “We’re excited to be operating on U.S. shores, where ...
(Date:3/23/2017)... , ... March 23, 2017 , ... ... for seniors, today announced rapid completion of the strategic executive team expansion needed ... notable additions to the ChenMed executive team,” says Christopher Chen, MD, ChenMed Chief ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... 2017  The U.S. Food and Drug Administration today ... of adults and pediatric patients 12 years and older ... have not received prior chemotherapy. This is the first ... of skin cancer. "While skin cancer is ... rare form called Merkel cell cancer have not had ...
(Date:3/23/2017)... , March 23, 2017   BioSpace , ... resource, has partnered with Indiana Biosciences Research Institute ... organizations and educational institutions to bring the state,s ... first-ever BioIndiana Hotbed map, an artistic representation of the ... was presented to Vice President Mike Pence , ...
(Date:3/23/2017)... Texas , March 23, 2017  Digital ... www.digitalpharmacist.com ), a rapidly growing digital health ... a mobile app that allows patients to manage ... multi-store locations such as Denver Health Pharmacy, USave ... The acquisition helps Digital Pharmacist accelerate its product ...
Breaking Medicine Technology: