Navigation Links
Heart attack risk differs between men and women
Date:11/29/2011

CHICAGO Findings on coronary CT angiography (CTA), a noninvasive test to assess the coronary arteries for blockages, show different risk scenarios for men and women, according to a study presented today at the Radiological Society of North America (RSNA).

Coronary artery disease (CAD) is a narrowing of the blood vessels that supply blood and oxygen to the heart. It is caused by a build-up of fat and other substances that form plaque on vessel walls. According to the Centers for Disease Control and Prevention, heart disease is the leading cause of death for both men and women in the U.S.

Researchers at the Medical University of South Carolina analyzed the results of coronary CTA on 480 patients, mean age 55, with acute chest pain. Approximately 65 percent of the patients were women, and 35 percent were men. The possibility of acute coronary syndrome was ruled out for each of the patients.

Using coronary CTA, the researchers were able to determine the number of vessel segments with plaque, the severity of the blockage and the composition of the plaque.

"The latest CT scanners are able to produce images that allow us to determine whether the plaque is calcified, non-calcified or mixed," said John W. Nance Jr., M.D., currently a radiology resident at Johns Hopkins Hospital in Baltimore, Md.

By comparing the coronary CTA results with outcome data over a 12.8-month follow-up period, the researchers were able to correlate the extent, severity and type of plaque build-up with the occurrence of major adverse cardiac events, such as a heart attack or coronary bypass surgery. The statistical analysis tested all plaques combined (calcified, non-calcified and mixed) and each individual plaque type separately.

"We found that the risks for cardiovascular events associated with plaque were significantly different between women and men," Dr. Nance said.

Within the follow-up period, 70 of the patients experienced major adverse cardiac events, such as death, heart attack, unstable angina or revascularization. In total, 87 major adverse cardiac events occurred among the patients during the follow-up period.

When the outcome data were correlated with the CTA combined plaque findings, the results indicated that women with a large amount of plaque build-up and extensive atherosclerosis are at significantly greater cardiovascular risk than men.

Specifically, the risk for major adverse cardiac events was significantly higher in women than in men when extensive plaque of any kind was present or when more than four artery segments were narrowed.

"This research tells us that extensive coronary plaque is more worrisome in women than the equivalent amount in men," Dr. Nance said.

However, when analyzing risk factors associated with the presence of individual types of plaque, the risk for major adverse cardiac events was greater in men, compared to women, when their artery segments contained non-calcified plaque.

Dr. Nance said the new data suggested that the atherosclerotic process, or hardening of the arteries, is not necessarily linear and that more research is needed to better understand the disease.

"Our research confirms that coronary CTA provides excellent prognostic information that helps identify risk, but there are gender differences that need to be considered," Dr. Nance said.


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Related medicine news :

1. Heart Attack Severity May Depend on Time of Day
2. Lengthy Hospital Transfers May Hamper Heart Attack Care
3. Depression can lead to heart disease
4. Low-Cal Diet Cuts Fat Around Heart in Obese People: Study
5. Scientists identify key area that could sever communication between brain and heart in disease
6. Substance in cancer medicine could prevent heart attacks
7. Surgery May Boost Survival With Dangerous Heart Condition
8. How Much Salt Is Best for the Heart?
9. Physically Demanding Work Raises Heart Risk in Unfit Men: Study
10. Disparities in heart health to be addressed by national leaders at womens health summit
11. Severity of heart attack is dependent on the time of day
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2016)... Milford, PA (PRWEB) , ... May 02, 2016 , ... ... now available at MilfordMD Cosmetic Dermatology Surgery & Laser Center, in Milford, Penn. “Patients ... the office, have their unwanted fat treated and go home or back to work ...
(Date:5/1/2016)... (PRWEB) , ... May 02, 2016 , ... ... search for original 1968 Jimi Hendrix Merriweather Post Pavilion in Columbia, Maryland concert ... Hendrix concert poster. The concert was held on August 16. According to Hawley, ...
(Date:5/1/2016)... ... , ... Good Circle Insurance Agency of Mission Viejo, California recently introduced a ... verity of health, life and injury policies and this new plan allows coverage for ... insurance plans don’t cover chiropractic care, so we decided to create this new plan ...
(Date:4/30/2016)... ... April 30, 2016 , ... Saturday, April ... veterinarians’ global impact on public health. The World Veterinary Association (WVA) and the ... year have selected continuing education with a One Health focus, which emphasizes how ...
(Date:4/29/2016)... ... April 30, 2016 , ... ... products, announces the Pick Up Springboard, an automotive invention that improves the storage ... industry is worth $162 billion," says Scott Cooper, CEO and Creative Director of ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... , April 29, 2016 ... Review, H1 2016" market research report that provides ... with comparative analysis at various stages, therapeutics assessment ... of administration (RoA) and molecule type, along with ... It also reviews key players involved in the ...
(Date:4/28/2016)... Mich. , April 28, 2016   ... . Diplomat Pharmacy, Inc. (NYSE: DPLO), the nation,s ... has signed a definitive agreement to acquire Valley ... Specialty Pharmacy ("TNH"), a leading specialty pharmacy that ... Van Nuys, California . In 2015, TNH ...
(Date:4/28/2016)... YORK , April 28, 2016  The blood ... 275 million dollars, according to Kalorama Information and The ... typing, immunoassays and nucleic acid testing.  The healthcare research ... made progress in developing blood collection stations and in ... made in Kalorama Information,s report, Blood Testing ...
Breaking Medicine Technology: