Navigation Links
Heart attack patients who stop statin risk death, say McGill researchers

This release is available in French.

Patients discontinuing statin medication following an acute myocardial infarction (AMI) increase their risk of dying over the next year, say researchers at McGill University and the McGill University Health Centre (MUHC). Their study was published in a recent issue of the European Heart Journal.

Using data on British patients who survived an AMI and were still alive three months later, Dr. Stella Daskalopoulou and colleagues found that those who discontinued their statin medication were 88% more likely to die during the following year compared to those who had never been on the medication.

"Statins were found to be beneficial drugs," said Dr. Daskalopoulou, of McGill's Faculty of Medicine and the Department of Medicine and the Division of Clinical Epidemiology at the MUHC. "Patients who used statins before an AMI and continued to take them after were 16% less likely to die over the next year than those who never used them. So even if it appears that the statins failed to prevent your AMI, it is beneficial to continue taking them and potentially quite harmful to stop."

The large, population-based cohort study was conducted using UK data to take advantage of the medical records kept in the General Practice Research Database (GPRD), which collects information on the health of more than three million patients across the UK.

"In the general population the statin discontinuation rate within the first year of prescription is 30 percent. That's very high," Dr. Daskalopoulou continued. "Because statins are preventative drugs, patients may not feel the immediate benefit of taking them and sometimes stop. However, it looks like this might be quite a dangerous practice after an AMI."

The harmful effects of statin discontinuation may be the result of many different mechanisms, including individual patient characteristics, the researchers explained. "Regardless of the mechanism or explanation, physicians should be careful when assessing each patient's medication needs," Dr. Daskalopoulou said. "Patients also need to take their medications exactly as prescribed after an AMI. Statins in particular should only be withdrawn after an AMI under close clinical supervision."


Contact: Mark Shainblum
McGill University

Related medicine news :

1. University Hospitals Case Medical Center recognized by American Heart Association
2. Vitamin B, Folate Supplements Wont Help Heart
3. Ultrasound used to predict heart attack risk
4. Reaching the Heart Through the Wrist
5. Air Pollution Can Damage Heart, Blood Vessels, Too
6. Infant Heart Transplant Controversy Continues
7. Morpace Inc. Reports: Hispanic American Women Unaware of Heart Disease Threat
8. Kaiser Permanente - Stanford Heart Research Center Funded to Study Treatment Outcomes
9. Turbulence Predicts Death Risk for Heart Failure Patients
10. Fat Cell Protein Boosts Heart Attack Risk in Elderly
11. New implant device remotely monitors heart failure patients at Northwestern Memorial
Post Your Comments:
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... DMG Productions ... Ed Begley Jr., airing first quarter 2016 via Discovery Channel. Dates and show times ... the Province, and is in the business of producing and supplying medical marijuana pursuant ...
(Date:11/24/2015)... ... November 24, 2015 , ... It takes only three to five seconds to ... that the first impression be positive and reflects business values. If a client starts ... or want to return. They will also share their thoughts about a business with ...
(Date:11/24/2015)... ... 2015 , ... In response to recent news highlighting Oxycodone fraud, Novus Medical ... the United States grew 400 percent between 1999 and 2010, far more than the ... percent of all fatal drug overdoses. (1) , While oxycodone and the extended release ...
(Date:11/24/2015)... ... 2015 , ... The American Association of Poison Control Centers ... through donations on Tuesday, Dec. 1, 2015. Since 2012, the Tuesday following Thanksgiving ... to collaborate in improving their local communities and help give back in impactful ...
(Date:11/24/2015)... ... 24, 2015 , ... With Thanksgiving right around the corner, holiday travel season ... protect your family and vehicle. , According to the National Highway Traffic Safety Administration, ... is sharing the following safety tips from the NHTSA: , ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... Va. , Nov. 24, 2015  DILON Diagnostics ... have signed an agreement for DILON to distribute GE,s ... across the globe. The signing of this distribution agreement will ... NM750b Molecular Breast Imaging system and is considered an ... provide better healthcare solutions for clinicians and their patients. ...
(Date:11/24/2015)... 2015 . ... adds Latest Guidebook for Chinese Medical Device GMP ... in November 2015 to the medical devices market ... at . China ... global economies with a fifth population in the ...
(Date:11/24/2015)... , Nov. 24, 2015  Figure 1, a free ... share medical cases, has launched a new completely redesigned ... web version allows radiologists, who work primarily on a ... further engage with its radiologist user base, Figure 1 ... North America (RSNA) Annual Meeting. ...
Breaking Medicine Technology: