Navigation Links
Heart Failure Drug May Help More in Higher Doses
Date:11/18/2009

Study finds increase lowers chance of hospitalization or death

TUESDAY, Nov. 17 (HealthDay News) -- For people with heart failure, high doses of the drug losartan, an angiotensin-receptor blocker (ARB), reduce the risk for hospital admission and death, a new study shows.

Though ARBs are known to benefit people with heart failure, the study focused on whether dose level makes a difference. The findings were to be presented during the American Heart Association's annual meeting, Nov. 14 to 18, in Orlando, Fla., and were published online Nov. 17 in The Lancet.

The study included 3,846 people in 30 countries who had heart failure, a left-ventricular ejection fraction of 40 percent or less and intolerance to angiotensin-converting-enzyme (ACE) inhibitors. The participants were randomly assigned to take 50 or 150 milligrams a day of losartan (Cozaar).

After a median follow-up of 4.7 years, 43 percent of those in the high-dose group and 46 percent of those in the lower-dose group had died or were admitted to hospital for heart failure.

Overall, the higher dose of losartan reduced the risk for death or admission for heart failure by 10 percent, according to the study. When looked at separately, the risk for death was 6 percent lower for the high-dose group, and the risk for hospital admission for heart failure was 13 percent lower.

Kidney impairment, low blood pressure and hyperkalemia (high levels of blood potassium that can cause potentially fatal abnormal heart rhythm) were more common in the high-dose group, the study reported.

"These findings suggest that increased doses of an ARB are needed to achieve the maximum benefit for clinical outcomes and symptoms related to heart failure in this population," wrote Dr. Marvin A. Konstam, a cardiologist at Tufts Medical Center and Tufts University School of Medicine in Boston, and his fellow researchers.

More information<
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. New Heart Attack Treatment Guidelines Stress Coordination
2. Terumo Heart, Inc. Wins Top Healthcare Category Honors at AnnArbor.com's 5th Annual &#8216;Deals Of The Year' Award Ceremony
3. Study Reveals Evidence of Heart Disease in Ancient Egyptian Mummies
4. American College of Cardiology/American Heart Association Comment on the FDA Public Health Advisory Regarding a Drug Interaction Between Clopidogrel and Omeprazole
5. Your own stem cells can treat heart disease
6. Obesity Rolling Back Gains in Heart Health
7. The Mummies Curse: Heart Disease
8. Heartburn Drugs Can Thwart Popular Blood Thinner
9. Highlights of NHLBI-supported research presented at American Heart Associations Scientific Sessions
10. Newer heart devices significantly improve survival, complication rate and quality of life
11. Pitt part of $100 million NHLBI Bench to Bassinet effort in congenital heart disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... 25, 2014 The global HCIT outsourcing ... 7.6%, to reach $50.4 billion by 2018 from $35 ... industry, and pharmaceutical industry are driving the HCIT outsourcing ... enhance their focus on core business, reduce operational and ... staff (further reducing hiring and training costs), share risk, ...
(Date:10/25/2014)... 2014 Background: , In 1998 Bob ... is a pioneer in the field of establishing recovery community ... treatment system and when he retired, he set out to ... public service. , 1. Where are the ... them? , 2. Can the recovery community be organized ...
(Date:10/25/2014)... TX (PRWEB) October 25, 2014 ... Chinese Molecular Diagnostics Industry, 2009-2019 is a ... and Chinese Molecular Diagnostics industry. The report ... Diagnostics including its classification, application and manufacturing ... China’s top manufacturers of Molecular Diagnostics listing ...
(Date:10/25/2014)... York, New York (PRWEB) October 25, 2014 ... transvaginal mesh lawsuits ( http://www.vaginalmeshlawsuit2015.com/ ) filed ... litigation underway in U.S. District Court, Southern District ... for Summary Judgment on Punitive Damages in a ... plaintiffs. In a ruling issued on October 21st, ...
(Date:10/25/2014)... blood supply to an arm or a leg before heart ... according to a new study. "During heart surgery ... to be able to operate on it. After some time ... produce energy because it doesn,t get oxygen. When we shut ... an arm or a leg, the body prepares for an ...
Breaking Medicine News(10 mins):Health News:Global HCIT Outsourcing Market to Grow at 7.6% CAGR to 2018 Says a Premium Research Report Available at ReportsnReports.com 2Health News:Global HCIT Outsourcing Market to Grow at 7.6% CAGR to 2018 Says a Premium Research Report Available at ReportsnReports.com 3Health News:Global HCIT Outsourcing Market to Grow at 7.6% CAGR to 2018 Says a Premium Research Report Available at ReportsnReports.com 4Health News:CCAR Accepting Nominations for the Bob Savage Recovery Advocate of the Year Award 2Health News:Global and China Molecular Diagnostics Industry Analysis to 2019 is Now Available at RnRMarketResearch.com 2Health News:Global and China Molecular Diagnostics Industry Analysis to 2019 is Now Available at RnRMarketResearch.com 3Health News:Global and China Molecular Diagnostics Industry Analysis to 2019 is Now Available at RnRMarketResearch.com 4Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 2Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 3Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 4Health News:Brief Interruption of Blood Supply to Limb Might Aid Heart Surgery: Study 2
... 13 The National Council on,Disability (NCD) will release ... Care System: Barriers to Success and Proposed,Policy Solutions, at ... at,the U.S. Department of Health and Human Services, 200 ... open to the public and the,media and free of ...
... CINCINNATI, Feb. 13, 2008 The Procter & Gamble Company,(NYSE: PG ... J. Johnson, 61, chief legal officer, will retire on June 1, 2008 ... Steven W. Jemison, 56, currently deputy general counsel, will succeed ... John P. Goodwin, 44, currently vice president - finance and ...
... been chosen as a NEO Success Award Winner for ... row that Antares has won this,prestigious award., Since ... top,public, private and emerging companies by revenue and employment. ... of business to,Northeast Ohio,s economic vitality., "Winning the ...
... R.I. - Screening all emergency room patients for carbon ... that can be done even in a high-volume urban ... Rhode Island Hospital. , In the largest study of ... emergency department were routinely screened for exposure to carbon ...
... system for tracking the movement of,the prostate during ... Seattle,Cancer Care Alliance. Featuring tiny GPS-type positioning transponders,implanted ... of the,prostate in real time and alerts technicians ... can adjust the external beam of,radiation., The ...
... editors of the Proceedings of the National Academy of ... the 2007 Cozzarelli Prize, an award for papers that ... , The award was established in 2005 as the ... Cozzarelli Prize in 2007 to honor late PNAS Editor-in-Chief ...
Cached Medicine News:Health News:National Council on Disability to Make Recommendations on Youth with Disabilities in the Foster Care System 2Health News:Procter & Gamble Announces Organizational Changes 2Health News:Antares Management Solutions 2008 NEO Success Award Winner 2Health News:Routine screenings uncover hidden carbon monoxide poisoning 2Health News:Routine screenings uncover hidden carbon monoxide poisoning 3Health News:GPS for the Prostate: System Keeps Radiation Therapy on Target 2Health News:PNAS announces 2007 Cozzarelli Prize recipients 2
(Date:10/25/2014)... Research ... addition of the  "Global and Chinese Acne ... their offering.       (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... Industry Report 2014 is a professional and ... the global acne medication industry with a ...
(Date:10/25/2014)... , Oct. 24, 2014  As the building ... a company access to diverse skill sets and ... round-the clock business hours for efficiency. However, effectively ... According to recent research, more ... as seeing a project not move forward due ...
(Date:10/22/2014)... 2014  Rescheduling of hydrocodone combination products (HCPs) ... market, according to a new primary market research ... market research and consultation exclusively in the area ... http://photos.prnewswire.com/prnh/20141021/153440 In August, the ... products from Schedule III to Schedule II status. ...
Breaking Medicine Technology:Global and Chinese Acne Medication Industry Report 2014 2Global and Chinese Acne Medication Industry Report 2014 3Work Around the Clock: Successfully Building & Managing Global Virtual Teams 2Hydrocodone: Rescheduled, Repositioned & Reinvented 2Hydrocodone: Rescheduled, Repositioned & Reinvented 3
... If you,re thinking about cosmetic surgery, your first stop ... into the future.   SculptMyDream.com is the first website ... using actual 3D photography.  Not only will this help you ... who can turn that dream into reality. (Photo: ...
... Solutions is showcasing its RFSuite RFID tracking and verification ... an RFSuite Symposium Monday, August 1st, from 12:30 – ... Waterfront, Vancouver. The event will include lunch, pre-registration is ... to view the invitation and register . CIVCO,s RFSuite ...
Cached Medicine Technology:See the Results of Your Breast Augmentation, Before Surgery 2CIVCO Showcases RFSuite RFID Tracking and Verification System at AAPM 2011 Booth #817 2CIVCO Showcases RFSuite RFID Tracking and Verification System at AAPM 2011 Booth #817 3
The Alexander McQueen eyewear collection focuses on a distinctive sophisticated style, with feminine lines, assertive shapes and original silhouettes....
QC HGB is an assayed quality control material for Hemocue analyzers. This control is a solution of stabilized human red cells and is available in 3 levels for monitoring analyzer performance at sever...
... EP is the first and only contact ... just beginning to have difficulty reading small ... everyone wants to enjoy the best vision ... or reading glasses. Fortunately, Biomedics EPs unique ...
... The table-mounted knee ... exposure for total knee ... flexible, open-frame design allows ... the knee during the ...
Medicine Products: