Navigation Links
Heart Disease and Depression Up Heart Failure Risk
Date:4/13/2009

Use of antidepressants makes little difference, study finds

MONDAY, April 13 (HealthDay News) -- Depression increases the risk that people with heart disease caused by blockage of coronary arteries will develop heart failure, a new study finds.

That finding was to be expected, said Heidi May, an epidemiologist at the Intermountain Medical Center in Murray, Utah, and lead author of the study, because earlier research had found that depression increases the risk of heart failure in otherwise healthy people. Heart failure is a progressive loss of the ability to pump blood.

What was not expected was the finding that treatment with antidepressant drugs did not reduce the risk of heart failure among people with depression in the group May studied -- 13,708 people who were diagnosed with coronary artery disease.

"I was surprised about that," May said. "Since antidepressants reduce the symptoms of depression, you would think that they would decrease the risk of heart failure." A report on the findings is in the April 21 issue of the Journal of the American College of Cardiology.

Ten percent of the people in the study --1,377 of them -- were struck by depression after being diagnosed with heart disease. The incidence of heart failure in that group was double the rate among those who did not have depression. The increased incidence was lower after adjustment for other risk factors, such as high blood pressure and diabetes, but it was still 50 percent higher.

Medication records were available for 7,719 people in the study, and those records showed no difference in the incidence of heart failure between people prescribed antidepressants and those not prescribed the drugs.

The lesson for physicians, May said, is that there is increased danger for people with heart disease and depression, even if they take medicine that reduces the symptoms of depression. Earlier studies have found that people with depression are less likely to follow recommendations for heart health, such as dieting properly and exercising, and that doctors should emphasize the need for them to follow the rules, she said.

May also said that the same kind of study should be done "in other patient populations to see if the results will be replicated."

Though this was not a controlled trial, considered the gold standard of medical research, the failure to find a protective effect of antidepressant drugs against heart failure "is both new and discouraging," said Dr. Redford Williams, director of the Behavioral Medicine Research Center at Duke University.

"But the study leaves open the possibility that other interventions, such as behavioral therapy, might have an effect," he said. "That is pure speculation on my part. But cognitive behavioral therapy, which teaches patients coping skills to deal with negative thoughts, might be effective."

Williams quickly acknowledged having a personal and financial interest in having that speculation prove true. He said he has developed a life skills program that has shown effectiveness in a clinical trial. If antidepressant medications don't work, such a program might help, he said.

More information

The U.S. National Institute of Mental Health has more on depression.



SOURCES: Heidi May, Ph.D., epidemiologist, Intermountain Medical Center, Murray, Utah; Redford Williams, M.D., director, Behavioral Medicine Research Center, Duke University, Durham, N.C.; April 21, 2009, Journal of the American College of Cardiology


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Walnuts and Fish Protect Against Heart Disease in Different Ways, According to Newly Published Loma Linda University Research
2. Marathoners Go the Distance on Heart Health
3. Molecule prompts damaged heart cells to repair themselves after a heart attack
4. New Research Suggests Drinking as Little as One Cup of Black Tea Per Day May Help Maintain Cardiovascular Function and Heart Health
5. Heartburn medications do not ease asthma symptoms
6. Wiley-Blackwell and the American Heart Association present new book series
7. Heartburn Sufferers Find Lasting Relief With TUMS(R) Dual Action
8. GOCEs heart starts beating
9. Cordex Pharma to Collaborate with BG Medicine in a Clinical Study of Heart Failure Biomarkers
10. Exercise is safe, improves quality of life in patients with chronic heart failure
11. Heart Transplant Failures More Likely in Poor, Minority Kids
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Heart Disease and Depression Up Heart Failure Risk
(Date:5/26/2016)... ... 26, 2016 , ... Catalent Pharma Solutions, the leading global ... and global clinical supply services, today announced two key appointments and the opening ... and strategic growth plans in the Asia Pacific region. , Howard Kim has ...
(Date:5/26/2016)... CA (PRWEB) , ... May 26, 2016 , ... In an effort to provide hair ... available to both Snapchat users and those who do not use the app. Dr. Mohebi, ... his new page, Dr. Mohebi Live . , Dr. Mohebi says, “The positive ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... for eating disorders, is opening a brand new child and adolescent residential treatment ... and their families with even more specialized eating disorder treatment and access to ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... multitude of activities from daily practices, arts & crafts, discussions, and games all ... East-D’Anna and Christy Evans have combined backgrounds in kids’ yoga, collegiate sport yoga ...
(Date:5/26/2016)... ... May 26, 2016 , ... Eugene Batelli, ... Along with his wonderful accolades and stellar patient reviews, Dr. Batelli continues to ... , Dr. Eugene Batelli is a highly trained Podiatric Surgeon who specializes in ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... , May 25,2016 FDA ... near-infrared Cellvizio platform for urological and surgical applications ... MKEAY) inventor of Cellvizio®, the multidisciplinary confocal laser ... milestone in the US with the 12 th ... Drug Administration (FDA). This new FDA clearance covers ...
(Date:5/25/2016)... , Germany and GERMANTOWN, ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: ... licensing and co-development agreement with Therawis Diagnostics GmbH to develop ... be to develop and market PITX2 as a marker to ... high-risk breast cancer patients. "We are pleased to ...
(Date:5/25/2016)... According to market research "Global ... Demand Forecast to 2022 - Industry Insights by Type ... by P&S Market Research, the global insulin delivery device ... it is expected to grow at a CAGR of ... segment is expected to witness the fastest growth at ...
Breaking Medicine Technology: