Navigation Links
Heart Disease and Depression Up Heart Failure Risk
Date:4/13/2009

Use of antidepressants makes little difference, study finds

MONDAY, April 13 (HealthDay News) -- Depression increases the risk that people with heart disease caused by blockage of coronary arteries will develop heart failure, a new study finds.

That finding was to be expected, said Heidi May, an epidemiologist at the Intermountain Medical Center in Murray, Utah, and lead author of the study, because earlier research had found that depression increases the risk of heart failure in otherwise healthy people. Heart failure is a progressive loss of the ability to pump blood.

What was not expected was the finding that treatment with antidepressant drugs did not reduce the risk of heart failure among people with depression in the group May studied -- 13,708 people who were diagnosed with coronary artery disease.

"I was surprised about that," May said. "Since antidepressants reduce the symptoms of depression, you would think that they would decrease the risk of heart failure." A report on the findings is in the April 21 issue of the Journal of the American College of Cardiology.

Ten percent of the people in the study --1,377 of them -- were struck by depression after being diagnosed with heart disease. The incidence of heart failure in that group was double the rate among those who did not have depression. The increased incidence was lower after adjustment for other risk factors, such as high blood pressure and diabetes, but it was still 50 percent higher.

Medication records were available for 7,719 people in the study, and those records showed no difference in the incidence of heart failure between people prescribed antidepressants and those not prescribed the drugs.

The lesson for physicians, May said, is that there is increased danger for people with heart disease and depression, even if they take medicine that reduces the symptoms of depression. Earlier studies have found that people with depression are less likely to follow recommendations for heart health, such as dieting properly and exercising, and that doctors should emphasize the need for them to follow the rules, she said.

May also said that the same kind of study should be done "in other patient populations to see if the results will be replicated."

Though this was not a controlled trial, considered the gold standard of medical research, the failure to find a protective effect of antidepressant drugs against heart failure "is both new and discouraging," said Dr. Redford Williams, director of the Behavioral Medicine Research Center at Duke University.

"But the study leaves open the possibility that other interventions, such as behavioral therapy, might have an effect," he said. "That is pure speculation on my part. But cognitive behavioral therapy, which teaches patients coping skills to deal with negative thoughts, might be effective."

Williams quickly acknowledged having a personal and financial interest in having that speculation prove true. He said he has developed a life skills program that has shown effectiveness in a clinical trial. If antidepressant medications don't work, such a program might help, he said.

More information

The U.S. National Institute of Mental Health has more on depression.



SOURCES: Heidi May, Ph.D., epidemiologist, Intermountain Medical Center, Murray, Utah; Redford Williams, M.D., director, Behavioral Medicine Research Center, Duke University, Durham, N.C.; April 21, 2009, Journal of the American College of Cardiology


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Walnuts and Fish Protect Against Heart Disease in Different Ways, According to Newly Published Loma Linda University Research
2. Marathoners Go the Distance on Heart Health
3. Molecule prompts damaged heart cells to repair themselves after a heart attack
4. New Research Suggests Drinking as Little as One Cup of Black Tea Per Day May Help Maintain Cardiovascular Function and Heart Health
5. Heartburn medications do not ease asthma symptoms
6. Wiley-Blackwell and the American Heart Association present new book series
7. Heartburn Sufferers Find Lasting Relief With TUMS(R) Dual Action
8. GOCEs heart starts beating
9. Cordex Pharma to Collaborate with BG Medicine in a Clinical Study of Heart Failure Biomarkers
10. Exercise is safe, improves quality of life in patients with chronic heart failure
11. Heart Transplant Failures More Likely in Poor, Minority Kids
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Heart Disease and Depression Up Heart Failure Risk
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: ... “America On The Brink” is the creation of published author, William Nowers. ... As a WWII veteran, he spent thirty years in the Navy. Following ...
(Date:10/12/2017)... ... 12, 2017 , ... The company has developed a suite ... regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been developed ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... drug delivery system that we intend to develop to enable prevention of a ... lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss ...
(Date:10/12/2017)... Chapel, FL (PRWEB) , ... October 12, 2017 , ... ... is holding a treadmill relay – Miles by Moonlight to raise money for the ... donating $300 or more. , Teams will work together to keep their treadmills ...
(Date:10/12/2017)... ... 2017 , ... Vohra Chief Medical Officer Dr. Shark Bird, ... nursing facility medical directors and other clinicians at various events in October. His ... many of these conferences we get to educate other physicians, facility nurses, corporate ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... 2017  In response to the nationwide opioid ... Surgeons (AAOMS) released prescribing recommendations that urge ibuprofen ... as a first-line therapy to manage a patient,s ... Recognizing the value and importance of ... Prescribing: Acute and Postoperative Pain Management" stresses that ...
(Date:10/2/2017)... -- Eli Lilly and Company (NYSE: LLY ) ... of 2017 on Tuesday, October 24, 2017. Lilly will ... the investment community and media to further detail the ... begin at 9 a.m. Eastern time. Investors, media and ... the conference call through a link that will be ...
(Date:9/28/2017)... 2017 Cohen Veterans Bioscience and Early Signal ... wearable and home sensors for real-time monitoring of patients ... a nonprofit organization focused on disruptive health solutions for ... analytical system to record and integrate behavioral, cognitive, physiological ... ...
Breaking Medicine Technology: