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Heart: Cardiac PET/MR measures up to PET/CT
Date:6/10/2013

Vancouver, British Columbia Just a few years ago, integrated positron emission tomography and magnetic resonance (PET/MR) imaging was found only in research institutes, but little by little the technology has expanded into clinical practice. This is especially true for cardiac indications, for which the highly sensitive soft tissue contrast of MR and the functional and metabolic imaging of PET are particularly valuable. New research proves the value of PET/MR compared to PET/computed tomography (CT) in cardiac applications, say researchers at the Society of Nuclear Medicine and Molecular Imaging's 2013 Annual Meeting.

PET/MR imaging techniques have advanced during the past several years, particularly in terms of disease detection and the correction of blurring (attenuation). PET/CT systems use CT to compensate for attenuation, and PET/MR employs MR. Part of this study compared the two to see how they match up. "Our research demonstrated that cardiac PET assessment for heart muscle viability using PET/MR yielded comparable results to PET acquired using PET/CT," said principal author Jeffrey M.C. Lau, MD, PhD, from Washington University in St. Louis, Mo. "It showed that MR can be used for PET attenuation correction in the same way that CT can."

This throws open doors for the technology in a variety of cardiac applications. In this instance, researchers used an imaging agent called F-18 fluorodeoxyglucose (F-18 FDG), which mirrors glucose as a source of fuel for heart and other cells that metabolize the agent readily. F-18 FDG-PET scans tell cardiologists about the metabolic activity of cardiac tissues and overall heart muscle function. This study focused on visualization of FDG in cardiac cells by PET/MR compared to PET/CT, which was found to be very similar. Comparable attenuation correction and imaging agent uptake measurements move PET/MR forward toward important clinical applications, including the use of PET/MR for imaging scarring of hear
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Contact: Susan Martonik
smartonik@snmmi.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

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