Navigation Links
'Healthy Fat' Chemical Aids Body's Metabolism
Date:9/19/2008

Mouse study uncovers new class of hormones that could reverse obesity-related disease

FRIDAY, Sept. 19 (HealthDay News) -- Scientists believe they have discovered a new class of hormones in mice, one of which may help stop or reverse obesity-related conditions such as insulin resistance and fatty liver, a new study says.

The Harvard School of Public Health researchers, whose work was published in the Sept. 19 issue of Cell, said their discovery -- if applicable to humans -- may allow the development of therapeutic or preventive treatments to counter rising obesity and resulting increases in potentially fatal metabolic disorders such as diabetes and atherosclerosis.

Lipokines, unlike other hormones which are steroid- or protein-based, were found in the fat cells of the genetically engineered mice. One of these hormones, "C16:1n7" or palmitoleate, appears to flag the muscles and liver to increase cell sensitivity to insulin and block fat accumulation in the liver. Palmitoleate also appeared to halt inflammation, a primary factor leading to metabolic disease.

The research team had noticed that genetically altered mice were remarkably resistant to the metabolic problems, like diabetes and heart disease, normally linked to a long-term, high-fat diet. In these mice, whose fat cells lacked proteins to chaperone the fat to their normal storage cells, palmitoleate production was much higher. The excess palmitoleate signaled the muscles and the liver to improve insulin function, so the cells could better absorb nutrients.

"We believe that it might be possible to chemically stimulate cells to manufacture their own 'good' fat, which could have beneficial effects on metabolism through increased palmitoleate signaling," lead researcher Gokhan Hotamisligil, a professor at the Harvard School of Public Health, said in a university news release.

If the palmitoleate effect is similar in people, Hota
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

1

GOOD

Page: 1 2

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Air pollution linked to cardiovascular risk indices in healthy young adults
4. Top Tips to Enjoy Healthy Latin Food Without Losing the Taste (Recipe)
5. Finicky Felines Award Four Stars to New Wellness(R) Healthy Indulgence Everyday Entrees
6. Keeping Kids Healthy and Fit: The New York Kids Club Launches a Revolutionary New Fitness Program
7. LifeMasters Provides Tips for Maintaining a Healthy Blood Cholesterol Level
8. On September 7th Local Organizations Partner to Celebrate Healthy Steps
9. September is Healthy Aging Month
10. Children who learn heart healthy eating habits lower heart disease risk
11. FDA: Use the Nutrition Facts Label to Make Healthy Food Choices
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... ID (PRWEB) May 22, 2013 Bodybuilding.com ... This Memorial Day (May 27, 2013) Bodybuilding.com will be donating ... of the amount. , “We are extremely grateful for ... the Armed Forces,” said Ryan DeLuca, CEO and founder of ... heroes who have sacrificed so much. Hire Heroes USA is ...
(Date:5/22/2013)... (PRWEB) May 22, 2013 Today, Zane ... Alabama Health Insurance Exchange . Zane Benefits, which provides ... benefits, is the leader in defined contribution plans ... to Zane Benefits’ website, beginning in 2014 as part ... for individuals and small businesses will become available through ...
(Date:5/22/2013)... HealthDay Reporter , , WEDNESDAY, May 22 (HealthDay News) ... deal of suffering, but new research indicates the combination ... entirely -- a smaller brain. , , Already aware ... depression, scientists wanted to determine if having both conditions ... -- about 2 percent -- isn,t alarming, study authors ...
(Date:5/22/2013)... Recent tragedies including the Oklahoma ... shooting in Newtown, Connecticut all resulted in serious, ... Emergency medical practitioners train to respond to both ... Services for Children (EMSC) Program specifically provides instruction, ... youngest patients. It is estimated 30 million children ...
(Date:5/22/2013)... loving child care is one of the most important things ... in their search, Paty’s Daycare has launched a new ... and much more. , “Our new website is vibrant, fun ... “Auntie Paty” Sutton, founder of Paty’s Daycare. “Just as you ... the first time that you walk through the front door ...
Breaking Medicine News(10 mins):Health News:In the Spirit of Memorial Day, Bodybuilding.com is Donating a Portion of Their Sales to Hire Heroes 2Health News:Zane Benefits Publishes New Information on Alabama Health Insurance Exchange 2Health News:Zane Benefits Publishes New Information on Alabama Health Insurance Exchange 3Health News:Having Both Migraines, Depression May Mean Smaller Brain 2Health News:Having Both Migraines, Depression May Mean Smaller Brain 3Health News:When Tragedies Impact Children – Kentucky Emergency Medical Services for Children (KYEMSC) Offers Specialized Training for Pediatric Emergency Care 2Health News:Paty’s Daycare Launches New Website to Connect with Parents in Need of Nurturing Child Care 2
... The largest single-institution study of its kind has found ... after surgery to remove the prostate. Men in this ... following surgery indicated their cancer had recurred. ... in Florida and Minnesota suggest that patients and their ...
... procedure extends survival of cancer patients, , MONDAY, Sept. 28 ... a healthy breast removed after being diagnosed with breast cancer ... that this practice is actually beneficial in terms of improving ... in Cancer . , The researchers, led by ...
... UofT researchers have used nanomaterials to develop a ... severity of a patient,s cancer so that the disease ... Their groundbreaking work, reported Sept. 27 in Nature ... will become commonplace. "This remarkable innovation is an ...
... University School of Medicine (BUSM) are recommending that menopausal ... to having their annual mammogram screenings. These recommendations appear ... Journal of the North American Menopause Society . ... reduction in breast cancer mortality in women older than ...
... ... Research , ... September 28, 2009 -- Axiom Accelerated Patient Recruitment (Axiom), one of the ... messaging (SMS) services. , , , , ,"Mobile device outreach is the future of ...
... At ... Hell Doctors will join with their supporters in Washington D.C.,s Lafayette Park. , ... Washington, DC (PRWEB) September 28, 2009 --, ... single-payer advocacy tour, the Mad As Hell Doctors from Portland, Oregon will hold ...
Cached Medicine News:Health News:Mayo researchers find few side effects from radiation treatment given after prostate cancer surgery 2Health News:Mayo researchers find few side effects from radiation treatment given after prostate cancer surgery 3Health News:More Women Having Other Breast Removed 2Health News:More Women Having Other Breast Removed 3Health News:U of T researchers create microchip that can detect type and severity of cancer 2Health News:Researchers believe hormone therapy should not be stopped prior to mammograms 2Health News:Axiom Accelerated Patient Recruitment Rolls Out 2Health News:Mad As Hell Doctors to Hold Final "White Ribbon Rally" for Single Payer in Washington, D.C. on September 30th 2Health News:Mad As Hell Doctors to Hold Final "White Ribbon Rally" for Single Payer in Washington, D.C. on September 30th 3
(Date:5/22/2013)... TORONTO , May 22, 2013 /PRNewswire/ ... announced three presentations demonstrating the superiority of the AE37 ... Antigen Express, Inc. ( www.antigenexpress.com ). The presentations will ... Society of Clinical Oncology (ASCO) to be held in ... June 4, 2013. The presentation entitled " ...
(Date:5/22/2013)... , 22. Mai 2013  Grifols, ein ... Barcelona , Spanien, präsentierte ... eine höhere Dosis von PROLASTIN©-C (Alpha1-Proteinasehemmer [human]) ... Alpha1-Antitrypsinmangel (AAT) auf ein Niveau anhebt, das ... Bereichs liegt. ATT-Mangel ist eine lebensbedrohliche, genetische ...
(Date:5/22/2013)... , May 22, 2013  Medifocus, Inc. (OTCQX: MDFZF and ... , Chief Operating Officer, will present at the Second Annual ... New York City at the Grand ... to begin at 4:00 p.m. EDT and will be available ...   http://wsw.com/webcast/marcum/mfs.v/   For more information and registration, ...
Breaking Medicine Technology:Generex Announces ASCO Presentations on the Antigen Express Advanced Stage AE37 Cancer Vaccine 2Generex Announces ASCO Presentations on the Antigen Express Advanced Stage AE37 Cancer Vaccine 3Generex Announces ASCO Presentations on the Antigen Express Advanced Stage AE37 Cancer Vaccine 4Studie von Grifols zeigt, dass eine höhere Dosis von PROLASTIN-C den Alpha1-PI-Spiegel in Patienten mit AAT-Mangel in den normalen Bereich anhebt 2Studie von Grifols zeigt, dass eine höhere Dosis von PROLASTIN-C den Alpha1-PI-Spiegel in Patienten mit AAT-Mangel in den normalen Bereich anhebt 3Studie von Grifols zeigt, dass eine höhere Dosis von PROLASTIN-C den Alpha1-PI-Spiegel in Patienten mit AAT-Mangel in den normalen Bereich anhebt 4Medifocus, Inc. to Present At The Second Annual Marcum LLP MicroCap Conference 2Medifocus, Inc. to Present At The Second Annual Marcum LLP MicroCap Conference 3
... 48-week investigational regimen yielded nearly double SVR rate ... protease inhibitor SCH 900518 presented at EASL annual ... SGP ) today reported that final ... its investigational oral hepatitis C protease inhibitor, in ...
... Potential of Fully Human Anti-PS Antibodies and ... Equivalent to the Human Antibody Inhibited Tumor ... More than 90%-DENVER and TUSTIN, Calif., April ... PPHM), a clinical stage biopharmaceutical company ...
Cached Medicine Technology:Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 2Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 3Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 4Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 5Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 6Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 7Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 8Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 9Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 10Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 11Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients 12Data Presented at AACR Annual Meeting Show Anti-Tumor Activity of Peregrine's Fully Human Anti-PS Antibody in Prostate Cancer Model 2Data Presented at AACR Annual Meeting Show Anti-Tumor Activity of Peregrine's Fully Human Anti-PS Antibody in Prostate Cancer Model 3Data Presented at AACR Annual Meeting Show Anti-Tumor Activity of Peregrine's Fully Human Anti-PS Antibody in Prostate Cancer Model 4
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: