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Health care research: $1.6 million in new funding for University of Montreal
Date:7/12/2010

eal Department of Chemistry and a scientist at the Institute for Research in Immunology and Cancer (IRIC), will receive $441,905 in support to study the histone deacetylase (HDAC) or enzymes that modify newly synthesized histones to improve the therapeutic use of HDAC inhibitors and facilitate the development of novel and more specific inhibitors in clinical settings. He will collaborate with Alain Verreault, a professor at the Department of Pathology and Cell Biology who is also an IRIC scientist.

Julian X. Zhu, a professor at the University of Montreal Department of Chemistry and Canada Research Chair in Polymer Biomaterials, will obtain $453,800 to study new polymer resins made from natural compounds for dental applications. The dental resins are based on natural compounds such as bile acids in the body. They are expected to be more biocompatible and less toxic than the dental amalgam that contains mercury or currently used polymer resins containing bis-phenol A, a compound listed by Health Canada as a dangerous substance in 2008. Publication of the first papers on this research and the possible use of natural compounds in dental composites received much media and public attention in 2009. This work will help to get the new resins closer to clinical use. Professor Zhu will collaborate with Professor Daniel Fortin of the University of Montreal Faculty of Dental Medicine and Professor Sophie Lerouge of the University of Montreal Hospital Research Centre. They intend to establish industrial collaborations for the formulation and testing of their dental composites.


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Contact: Sylvain-Jacques Desjardins
sylvain-jacques.desjardins@umontreal.ca
514-343-7593
University of Montreal
Source:Eurekalert

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