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Headaches in lupus patients not linked to disease activity study says
Date:10/27/2013

ndicate that at the commencement of the study nearly 18% of participants had headache61% with migraine, 37% tension, 7% intractable non-specific, 3% cluster and 1% intracranial hypertension. After 10 years researchers found that the proportion of patients who ever reported a headache increased to 58% , with only 2% of subjects reporting a "lupus headache" that is described by the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI) as a "severe, persistent headache: which may be migrainous, but unresponsive to narcotic analgesia."

Researchers found no association between headache and specific lupus autoantibodies or lupus medications such as steroids, antimalarials, and immunosuppressives. "While lupus patients with headaches reported lower quality of life, the majority of cases resolved on their own without lupus-specific therapies," concludes Dr. Hanly.

In a related editorial, Dr. Michael Lockshin, with Weill Cornell Medical College and Hospital for Special Surgery in New York, agrees, "Hanly et al. strongly suggest that lupus headache is not a sign of disease activity, but may be linked to other neurological manifestations. The current headache SLEDAI criterion no longer seems to be useful and should be discarded as a method for evaluating lupus flares."


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Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

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