Navigation Links
Harvard expert on inflammation's role in obesity receives Columbia's 2010 Naomi Berrie Award
Date:11/19/2010

ers of especially promising young diabetes investigators. Each year, the recipient a senior scientist outside Columbia who has made major contributions to diabetes research is given $100,000 to support a two-year research fellowship for a student or research fellow in his or her laboratory. The second $100,000 award supports a research fellow at Columbia.

Dr. Hotamisligil Focuses on Immune Response and Underlying Mechanisms of Obesity

Recent years have witnessed a significant revision of the traditional view that fat cells simply store excess energy. Studies by Dr. Hotamisligil and his associates, as well as many others, have demonstrated that adipose tissue produces and regulates many metabolic and hormonal signals, generating profound effects on a body's endocrine equilibrium and in the development of diabetes.

Dr. Hotamisligil's research has played a preeminent role in the emergence of the concept that chronic inflammation is central to obesity and associated metabolic disorders, especially insulin resistance and type 2 diabetes. He developed one of the models designed to definitively link inflammation, immune response and insulin action when he discovered that JNK (Jun N-terminal kinase), a protein that influences DNA transcription and other cellular processes, is implicated in the control of expression of many genes involved in immune response On a cellular level, he has also identified the endoplasmic reticulum as a locus integrating nutrient and stress responses and its dysfunction as an important mechanism underlying obesity and type 2 diabetes.

Dr. Hotamisligil made early observations regarding cytokine production in adipose tissue, and has used these insights to understand the mechanisms that connect cytokine action to defective insulin signaling. Recently, his group identified an important connection between nutrients, JNK activity and endoplasmic reticulum function stress through a pathogen-sensing molecule. He has
'/>"/>

Contact: Alex Lyda
alyda@columbia.edu
212-305-0820
Columbia University Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Solutions for Sleep Problems: Harvard's Improving Sleep Special Health Report and New Sleep Apnea Video
2. Partners Harvard Medical International Set to Play Key Role as Saudi Arabia Pursues Ambitious Health Care Transformation
3. PrescriptionDrugs.com and Mike “Zappy” Zapolin Have Been Selected to Compete in Harvard Business School New Venture Contest
4. Harvard Medical School releases 2010 Annual Report on Prostate Diseases
5. Harvard School of Public Health unveils comprehensive, public online library of firearms research
6. Uninsured get poor care for migraine: Harvard study
7. Boosting Mental Performance, from the Harvard Mental Health Letter
8. Harvard Health Letter Features Q&As from Harvard Doctors
9. OHSU joins forces with UO, Harvard to accelerate Fanconi anemia research
10. Color, Odor Changes in Urine Usually -- But Not Always -- Harmless, Reports Harvard Women's Health Watch
11. Celebrated Father Overcame Poverty and Mental Illness to Help His Son Earn a Scholarship to Harvard
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Deer Path of Huntley -- a BMA affordable assisted ... 3 p.m. to 4 p.m. on Feb. 13. , The community, ... adults with physical disabilities between the ages of 22 and 64. ... and sweetheart-themed karaoke. , For more information about the event or ...
(Date:1/22/2015)... Va. (PRWEB) January 22, 2015 Liberty University ... Counseling (M.A.) program from the Council for Accreditation ... program, part of Liberty’s Center for Counseling & Family ... founding dean of the university’s new School of Behavioral Sciences. ...
(Date:1/22/2015)... West Hollywood, California (PRWEB) January 22, 2015 The ... 22, 2015 at 10 a.m., to commemorate the 42nd anniversary of ... the United States. , “It’s been 42 years since the Roe ... to choose is still as present as ever,” said City of ...
(Date:1/22/2015)... Chemo Duck Program is pleased to announce the release of the ... with cancer. The Chemo Duck App, available on iTunes for use ... to help children of all ages living with cancer adjust to ... entertained, educated and at ease while waiting for clinic visits or ...
(Date:1/22/2015)... 23, 2015 VogueQueen is a seasoned and ... and many designers are thrilled to have it lead the ... its new collection of prom dresses for the global market. ... the strategic vision and he focuses on continuing the goal ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:Liberty University's Resident Master’s Counseling Program Receives CACREP Accreditation 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2
... Omnicell, Inc. (Nasdaq: OMCL ), a leading provider of system solutions ... 2009 to discuss Omnicell,s Third Quarter 2009 financial results. , ... conference call and webcast, When: October 22, ... Lipps, chairman, president and chief executive officer, ...
... calling on all Virginia restaurants and other workplaces to ... report by the Institute of Medicine (IOM) that concluded ... save lives. , (Logo: http://www.newscom.com/cgi-bin/prnh/20080918/CFTFKLOGO ) , The ... conclusive evidence that secondhand smoke causes heart disease and ...
... , NEW YORK, Oct. 16 It,s open enrollment ... healthcare and other benefits. Sometimes when a serious ... health or disability insurance. Here,s more on making ... battling a major illness. , Listen to this report ...
... SOS Assistance, Inc. today was awarded the contract to provide ... TRICARE Overseas Program. Since 1998, International SOS has supported TRICARE ... receive the highest quality care, no matter where their work ... Rico. , Under this new contract, which includes ...
... MILWAUKEE, Oct. 16 Delays in shipments from vaccine ... Wisconsin to suspend its seasonal flu vaccination clinics throughout ... , The Shoo the Flu & Pneumonia Too! ... The clinics will resume as soon as additional ...
... ... ... than 30 pediatric experts from Children’s National Medical Center will be presenting at ... – 19 in Washington. , , , , ,Children’s pediatric specialists will be discussing many ...
Cached Medicine News:Health News:Omnicell to Release Third Quarter 2009 Earnings Results on October 22 2Health News:Virginia Restaurants Urged to Go Completely Smoke-Free After Major Report Finds Smoke-Free Laws Prevent Heart Attacks 2Health News:Virginia Restaurants Urged to Go Completely Smoke-Free After Major Report Finds Smoke-Free Laws Prevent Heart Attacks 3Health News:International SOS Awarded TRICARE Overseas Program Contract 2Health News:Delays in Vaccine Shipments Will Force Suspension of Shoo the Flu Clinics 2Health News:Children's National Experts Presenting at American Academy of Pediatrics Conference, 2
(Date:1/23/2015)... MONMOUTH JUNCTION, N.J. , Jan. 23, 2015 ... immunotherapy company commercializing its CytoSorb® extracorporeal cytokine adsorber ... surgery patients, announced the receipt of $385,642, net ... approved participant of the Technology Business Tax Certificate ...
(Date:1/23/2015)... LONDON and BOSTON , January ... structure-guided drug discovery and development company, is delighted to announce ... has been awarded to Miles Congreve (Vice President ... co-founder) and Malcolm Weir (Chief Executive Officer and ...
(Date:1/22/2015)... 22, 2015  BiOptix is pleased to announce the appointment ... of Chemistry and Biochemistry. Scott joins the company after previous ... Amgen throughout the course of his nearly 20 year ... is a nationally recognized thought leader in the biosensor ...
Breaking Medicine Technology:CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 2Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 4BiOptix Expands Leadership Team with the Appointment of Dr. Scott Klakamp as Vice President of Chemistry and Biochemistry 2
... Traditionally, when choosing a non-contact diagnostic lens, ... wide field of view and high magnification. ... introduced by Volk Optical, doctors can have both ... widest field of view available in a non-contact ...
... is a 3.0mm single loaded suture anchor ... anchor barb catches on the cancellous bone ... "breaks" free. The small size is perfect ... used in rotator cuff repair where single ...
... Tac™ implantThe USS Sports Medicine™ E-Z Tac implant ... soft tissue to bone. The resorbable repair device ... bone and is used to reattach damaged soft ... a resorbable copolymer, a polyester derivative of lactic ...
... Soft Tissue Anchor 2 mm is a resorbable ... bone using sutures. The resorbable repair device is ... and is used to reattach damaged soft tissue. ... copolymer, derived from glycolide and lactide colored with ...
Medicine Products: