Navigation Links
Hard to heal bone fractures could benefit from CD34+ stem cell treatment
Date:12/4/2013

Durham, NC (PRWEB) December 04, 2013

A new study appearing in STEM CELLS Translational Medicine (SCTM) demonstrates the potential of a subset of stem cell called CD34+ in treating hard to heal bone fractures.

While most patients recover from broken bones with little or no complication, up to 10 percent experience fractures that won’t heal. This can lead to a number of debilitating side effects, from infection to bone loss, and it can require extensive treatment involving multiple operations and prolonged hospitalization as well as long-term disability.

Regenerating broken bone using stem cells could offer an answer. Adult human peripheral blood CD34+ cells have been shown to contain an abundance of a type of stem cell called endothelial progenitor cells (EPCs) as well as hematopoietic stem cells, which give rise to all types of blood cells. As such, they could be good candidates for this therapy.

However, while other types of stem cells had been tested for their bone regeneration potential, the ability of CD34+ to do so had never been reported on before the phase I/II clinical study was published in the current SCTM. It was conducted by researchers at Kobe University Graduate School of Medicine, led by Tomoyuki Matsumoto, M.D., and Ryosuke Kuroda, M.D., members of the university’s department of orthopedic surgery and its Institute of Biomedical Research and Innovation (IBRI).

The study was designed to evaluate the safety, feasibility and efficacy of autologous and G-CSF-mobilized CD34+ cells in patients with non-healing breaks, breaks that had not healed in nine months, in their legs. (G-CSF is a drug that releases stem cells from the bone marrow into the blood.) Seven patients were treated with the stem cells after receiving bone grafts.

“Bone union was successfully achieved in every case, confirmed as early as 16.4 weeks on average after treatment,” Dr. Kuroda said.

Dr. Matsum
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. HRT Update: Therapy May Reduce Fractures, Boost Some Risks
2. Two-Thirds of Osteo Hip Fractures Occur After 80: U.S. Study
3. Young Kids With Hip, Thigh Fractures Heal Well With Single-Leg Casts
4. Epilepsy drugs increase risk of fractures and falls
5. Higher Doses of Vitamin D Prevent Fractures in Older Women
6. New gene offers hope for preventive medicine against fractures
7. Steroid injection linked to increased risk of bone fractures
8. Method for assessing hand bone density may prevent hip fractures
9. Fractures Take High Toll on High School Athletes
10. Regenerative medicine: Clinical trials launched for the treatment of delayed union fractures
11. Skechers Lawsuit Has Been Filed by Wright & Schulte on Behalf of a Pennsylvania Woman Who Allegedly Sustained Multiple Arm Fractures Allegedly Due to Shape-Ups’ Defective
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... NJ Top Docs Presents Dr. Christophe Oliveira ... Top Doc, Dr. Christophe Oliveira, has just announced ... for the department of transportation. Dr. Oliveira has ... all drug testing for commercial drivers. , Having ... disorders including disk herniations, spinal stenosis, muscle sprains/strains, ...
(Date:8/28/2014)... (BRONX, NY) Researchers from Albert Einstein College of ... a potential antibody therapy for Sudan ebolavirus (SUDV), one of ... the Zaire ebolavirus (EBOV), is now devastating West Africa. First ... (most recently in 2012) that have killed more than ... ACS Chemical Biology . , Between 30 and 90 ...
(Date:8/28/2014)... In 2012, The Ben & Catherine Ivy Foundation ... brain cancer research projects at the Translational Genomics ... officially received the final regulatory approval from University ... for the trial can begin. , In the ... Trial," TGen and its clinical partners will lead ...
(Date:8/28/2014)... a Chinese herbal medication practitioner in Melbourne for ... a team of intensive care and emergency physicians ... who prescribe complementary medications. , Writing in ... Australasian College for Emergency Medicine, emergency medicine trainees ... the Intensive Care Unit at the Royal Melbourne ...
(Date:8/28/2014)... New York, New York (PRWEB) August 28, 2014 ... continue to mount in courts around the U.S., Bernstein ... & Gynecology is touting devices like Mirena as ideal ... from The Daily Press, the authors of the study ... comes to preventing pregnancy than other methods favored by ...
Breaking Medicine News(10 mins):Health News:NJ Top Docs Presents Dr. Christophe Oliveira of Rehabilitation Instiute of North Jersey 2Health News:NJ Top Docs Presents Dr. Christophe Oliveira of Rehabilitation Instiute of North Jersey 3Health News:Drug shows promise against Sudan strain of Ebola in mice 2Health News:TGen receives approval for patient enrollment in brain cancer clinical trial 2Health News:Deadly remedy: Warning issued about Chinese herbal medicine 2Health News:Mirena IUD Lawsuit News: Bernstein Liebhard LLP Notes New Study Touting IUDs as Ideal Birth Control for Teenage Girls 2Health News:Mirena IUD Lawsuit News: Bernstein Liebhard LLP Notes New Study Touting IUDs as Ideal Birth Control for Teenage Girls 3Health News:Mirena IUD Lawsuit News: Bernstein Liebhard LLP Notes New Study Touting IUDs as Ideal Birth Control for Teenage Girls 4
... a booster vaccination against H5N1 avian influenza given years after ... controlling a potential future pandemic. The study is published ... Infectious Diseases, now available online. , H5N1 continues to ... of mid-June, more than 60 percent of the more than ...
... ADDitude magazine,s top scientific,advisors investigate and explain non-drug ... green time and neurofeedback -,that may relieve ADHD ... how,nutrition, exercise and supplements can help treat ADHD ... magazine, the leading,publication for families and adults living ...
... boost,disability field,s quest to tie in public funding ... 16 One of the most complex,issues in ... and fund,services equitably to people with intellectual and ... Intensity Scale (SIS),assessment tool, developed by the American ...
... days of summer are here, and,for many, the rising ... an,estimated 40 percent of children and 20 percent of ... are spending three billion,dollars a year on antihistamines, often ... say in-vitro blood tests, the,latest generation of allergy tests, ...
... to irregular patterns of light and darkness can cause ... with the 24-hour solar day, negatively affecting human health ... the relationship between circadian disruptions and human maladies. ... Institute,s Lighting Research Center (LRC) provides a new framework ...
... Amsterdam, 16 July 2008 Elsevier, a leading publisher of ... Urology , the official journal of the European Association ... 5.634. , European Urology (also ... papers, fast response and an international profile. To keep up ...
Cached Medicine News:Health News:Booster vaccination may help with possible future avian influenza pandemic 2Health News:Booster vaccination may help with possible future avian influenza pandemic 3Health News:Treating ADHD Symptoms Without Medication: Free Special Report Examines Alternative ADHD Treatments 2Health News:The Supports Intensity Scale Assessment Can be Used to Build Robust Funding Methods for Developmental Disability Services, New Research Reveals 2Health News:New approach sheds light on ways Circadian disruption affects human health 2Health News:New approach sheds light on ways Circadian disruption affects human health 3
(Date:8/28/2014)... , Aug. 28, 2014 Telik, Inc. ... company that merged with MabVax Therapeutics, Inc. on ... significant progress related to the development of its ... was recovered using the Company,s internally developed antibody ... potential for multiple antibody based therapeutic and diagnostic ...
(Date:8/28/2014)... Aug. 28, 2014 Amgen (NASDAQ: ... License Application (BLA) to the U.S. Food and Drug ... of high cholesterol. Evolocumab is an investigational fully human ... (PCSK9), a protein that reduces the liver,s ability to ... the blood. 1 ­ ...
(Date:8/28/2014)... Aug. 28, 2014   RapidForce , an innovative ... a strategic partnership with professional tennis player John ... Isner wears RapidForce during competitions to help with knee ... week at the 2014 US Open Tennis Championships. ... Physio Hybrid Shapes are a revolutionary hybrid of a ...
Breaking Medicine Technology:Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 2Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 3Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 4Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 2Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 3Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 4Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 5Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 6Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 7Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 8Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 9America's top-ranked tennis player John Isner Joins Forces with RAPIDFORCE Physio Hybrid Shapes 2America's top-ranked tennis player John Isner Joins Forces with RAPIDFORCE Physio Hybrid Shapes 3America's top-ranked tennis player John Isner Joins Forces with RAPIDFORCE Physio Hybrid Shapes 4
... NEW ORLEANS, Dec. 5, 2011  At this week,s 46th ... Society of Health-System Pharmacists (ASHP), Cardinal Health launched ... initiatives by making it easier, more timely and cost ... can be scanned at the patient bedside. ...
... 2011  Pharmacy benefit managers Express Scripts and ... unions, and consumers between $51 billion and $87 billion ... a new report released today by economists Jonathan ... Compass Lexecon .  (Logo:  http://photos.prnewswire.com/prnh/20080827/EXPRESSSCRIPTSLOGO ...
Cached Medicine Technology:Cardinal Health Launches Innovative Barcode Administration Solution to Help Hospitals Bridge Gaps in Medication Safety 2Cardinal Health Launches Innovative Barcode Administration Solution to Help Hospitals Bridge Gaps in Medication Safety 3Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 2Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 3Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 4Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 5Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 6Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 7Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 8Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 9Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 10Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 11Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 12Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 13
Visualize the prostate in both transverse and longitudinal planes....
Super High Density 360 degree radial rectal transducer. High resolution in the near field and lower frequencies for deeper penetration make this transducer the optimal choice when scanning the anal c...
Multi-frequency, HST, linear transducer with a longer (60mm) footprint. Available with puncture adapter and water path. This transducer incorporates ALOKAs exclusive Hemispheric Sound Technology and ...
... high frequency (13Mhz) ... and superficial imaging. ... Hemispheric Sound Technology ... This multi-frequency transducer ...
Medicine Products: