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Hard To Treat Diseases (HTDS) Announces Initial Research Results on Potential MS Therapy

Research results with animal testing encouraging

BELGRADE, Serbia, Feb. 2 /PRNewswire-FirstCall/ - Hard to Treat Diseases (HTDS) announced the results of preliminary testing of a potential treatment for Multiple Sclerosis.

Testing involved the use of a combination of drugs; ribavirin and tiazofurin on animal test subjects. Administration of ribavirin and tiazofurin in combination attenuated or weakened the proliferation of autoreactive T lymphocytes and their infiltration into the nervous tissue that are involved in the destruction of myelin, oligodendrocytes and axons associated with MS. The tests succeeded in decreasing clinical symptoms and duration of the disease induced in experimental animals. These results are encouraging for the future MS therapy.

Also encouraging is the fact that the two drugs in question are currently used in treatment or undergoing clinical trials in relation to the treatment of other diseases. In particular, ribavirin is already in use in human clinical practice as an antiviral drug (VIRAZOL), and is very successful in treatment of respiratory syncicial virus in children, hepatitis C, SARS and HIV. Tiazofurin is in phase II of clinical trials as an anticancer drug.

Multiple sclerosis is a chronic disease with severe neurological symptoms, which often leads to complete disability and death. To date there is no suitable therapy for this heavy neurological disorder.

The company will provide further details as they become available.

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SOURCE Hard to Treat Diseases
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