Navigation Links
Hallmark Alzheimer's disease changes found in retinas of humans and imaged in live animals
Date:6/24/2010

ated a correlation between retinal plaques and brain plaques as disease progressed.
  • In the laboratory mice, a unique immune system-based therapy that reduces the amount of plaques in the brain also reduced plaque load in the retina to the same extent, suggesting that the retina could faithfully represent the brain in assessing response to therapy.
  • Beta-amyloid plaques were identified in retinal samples from human patients who had died from Alzheimer's disease, and their features correlated with the diagnosed stage of the disease. Importantly, plaques were clearly detected not only in patients who definitely had the disease, but also in the retinas of some people who were suspected of having early-stage Alzheimer's disease based on clinical diagnosis and microscopic examination of brain tissue after death.

    Together, the results offer the first evidence for the existence of Alzheimer's-specific plaques in the retina of human patients and the ability to detect individual plaques in live mouse models, creating a strong basis for future research building on these findings. According to the authors, these studies establish the potential of direct retinal beta-amyloid plaque imaging in live subjects as a tool for early Alzheimer's disease diagnosis and prognosis, as well as assessment of therapies.


    '/>"/>


  • Contact: Sandy Van
    sandy@prpacific.com
    808-526-1708
    Cedars-Sinai Medical Center
    Source:Eurekalert

    Page: 1 2 3

    Related medicine news :

    1. Hallmark Insights' Employer Survey Reveals Cost-Savings Benefits of Health & Wellness Programs
    2. Hallmark Insights Completes SAS 70 Type II Audit
    3. Blood stem-cell transplant regimen reverses sickle cell disease in adults
    4. New research identifies modifiable risk factors for heart disease
    5. Distinct demographic profiles between Crohns disease and ulcerative colitis
    6. Summit Medical Group hosts “Go Red Day” to Raise Awareness of Heart Disease and Stroke
    7. Keenan Selects Nurtur and Healthyroads for Integrated Disease Management and Personal Wellness Programs
    8. Michael J. Fox Foundation Awards $2.8 Million to Drive Development of Parkinsons Disease Biomarker Pipeline
    9. Tests showing smokers their individual risk of future disease will help them quit, says paper
    10. Researcher to track spread of disease, malware and power outages
    11. Texas Health Dallas Launches Screening Program for Female Heart Disease
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:7/12/2014)... City, Utah (PRWEB) July 12, 2014 ... two types of startups, with awards being bestowed to ... emphasis spotlighted Utah’s outstanding entrepreneur community with recognition for ... a sustainable model with incoming revenue. , 25 Under ... across the state that are under 5 years old. ...
    (Date:7/12/2014)... (PRWEB) July 12, 2014 A recent article ... provides a trio of suggestions for those seeking cosmetic ... days are rapidly approaching and the heat begins to enliven ... to their summer clothing, realizing that they didn’t work out ... , This can cause a sudden surge of people eager ...
    (Date:7/12/2014)... July 12, 2014 Wright & Schulte LLC, ... in Just For Men Lawsuits (case #59776/2014), announces they ... of reports that allege the popular hair dye, Just For ... to their face, neck and other areas. In addition to ... Men chemical burns , the advertisements being run by Wright ...
    (Date:7/12/2014)... (PRWEB) July 12, 2014 ... score of 4.1 out of 5. This above-average ... have been underpinning buyer negotiation power over the ... analyst Anna Son, “during the period, surging demand ... costs associated with new product development, have placed ...
    (Date:7/12/2014)... Augusta, GA (PRWEB) July 12, 2014 ... Nova Medical Centers, is pleased to announce that it ... , This new facility will join four Atlanta-based ... will be located at 3209 Deans Bridge Road, and ... Monday through Friday. , “With Nova’s treatment philosophy ...
    Breaking Medicine News(10 mins):Health News:SquareHook is Recognized for UVEF 25 Businesses Under 5 Years-Watch Out 2Health News:Best Summer Cosmetic Surgeries Revealed in Article By Seattle Plastic Surgeon 2Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 2Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 3Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 4Health News:Floor-Grade Instruments Procurement Category Market Research Report from IBISWorld has Been Updated 2Health News:Floor-Grade Instruments Procurement Category Market Research Report from IBISWorld has Been Updated 3Health News:Floor-Grade Instruments Procurement Category Market Research Report from IBISWorld has Been Updated 4Health News:Nova Medical Centers To Open New Facility in Augusta, Georgia 2
    ... 2.5% in 2007, BRAINTREE, Mass., Feb. 12 ... insurance was up +1.4% in,December, year-over-year. For the ... -2.5%, according to the MIB Life Index(SM). Despite ... was the only age group,to post 2007 year-to-date ...
    ... Protalix,BioTherapeutics, Inc. (Amex: PLX ), announced today ... the Nobel Prize in Chemistry,has been appointed to the ... member of the U.S. National Academy of Sciences,and the ... at Stanford University. He joined the faculty of Stanford ...
    ... of the late Dr. Frank Stanton, Former President of ... League (ARL) of,Boston has received a $3 million grant ... ARL of Boston,s 109-year-old history.,The Stanton Foundation was created ... former president of CBS and a noted philanthropist., , ...
    ... high-end ,infotainment, systems manufacturer to manage global ... manufacturing operations with Visiprise Manufacturing, ... leader in,integrated manufacturing execution (MES) solutions today ... Harman,International, has selected Visiprise Manufacturing as their ...
    ... the first and only soybean oil to provide the highest ... serving, and light, clean taste., IOWA CITY, Iowa, Feb. ... product that not only meets the increasing,consumer demand for low ... and neutral taste so important to food processors., Asoyia ...
    ... Board of the County of Shelby, Tennessee ... Health Systems, Inc.) ("Series 1985C Bonds") ... Board of the County of Shelby, Tennessee ... (Methodist Health Systems, Inc.) ("Series 1995 Bonds") ...
    Cached Medicine News:Health News:MIB Life Index Reports North American Life Insurance Activity Up 1.4% in December 2Health News:Protalix BioTherapeutics Appoints Professor Roger D. Kornberg to Board of Directors 2Health News:Protalix BioTherapeutics Appoints Professor Roger D. Kornberg to Board of Directors 3Health News:Photo: Animal Rescue League of Boston Receives $3 Million Grant to Establish a Center for Shelter Dogs 2Health News:Photo: Animal Rescue League of Boston Receives $3 Million Grant to Establish a Center for Shelter Dogs 3Health News:Harman/Becker Automotive Systems Completes Initial Deployments of Visiprise Integrated Manufacturing Execution 2Health News:Harman/Becker Automotive Systems Completes Initial Deployments of Visiprise Integrated Manufacturing Execution 3Health News:Asoyia Announces New Mid Oleic Ultra Low Lin Soybean Oil 2Health News:Methodist Healthcare - Memphis Hospitals Announces the Commencement of the Tender Offer for Certain Designated Maturities of: 2Health News:Methodist Healthcare - Memphis Hospitals Announces the Commencement of the Tender Offer for Certain Designated Maturities of: 3
    (Date:1/15/2014)... and Markets ( http://www.researchandmarkets.com/research/6k27gw/dental ) has announced the addition ... Analysis, Size, Share, Growth, Trends And Forecast, 2013 - ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ) Dental ... order to treat dental impairments, for tooth restoration and ...
    (Date:1/15/2014)... , Jan. 15, 2014 AARP Foundation today announced it ... adults suffering from the severe cold weather that has gripped ... to helping those in need; so to support these emergency ... up to $250,000, which could mean up to $500,000 in ...
    (Date:1/15/2014)... Corporation (the "Company") (NASDAQ: CLSN ) today ... to purchase an aggregate of approximately $15 million of ... offering, led by a dedicated health care fund. ... these investors pursuant to which the Company agreed to ...
    Breaking Medicine Technology:Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3
    ... Wire-Reinforced LMA ™ Airway., ,The ... tube which allows it to be ... while maintaining a good seal. This ... and dental surgery, or other procedures ...
    ... Versatile LMA™ Airway., ,The LMA ProSeal™ ... double cuff design enables seal pressures of ... The drain tube separates the alimentary and ... flexible airway tube, enable longer periods of ...
    ... superior, disposable supraglottic airway tool that utilizes ... design to provide the best non-intubating airway ... a safe, reliable, cost effective and efficient ... laryngoscopy is not feasible or attainable. With ...
    ... Available in even sizes 20-36F. Single use. ... patient comfort. The Latex-Free Robertazzi is the ... offering the best solution for latex sensitivity. ... offer a quality latex-free product as your ...
    Medicine Products: