Navigation Links
Half-million-dollar DNA sequencer to boost genetic science research at UH
Date:10/17/2007

HOUSTON, Oct. 17, 2007 Not too long ago, deconstructing and analyzing DNA codes took scientists several years and enough chemistry and computer hardware to fill the entire floor of a building. Now, a genetic sequencer the size of a washing machine can do the work in a couple of days.

Thanks to a $750,000 grant from the Cullen Foundation awarded to the University of Houstons Institute for Molecular Design (IMD), researchers will be among the first in the region to use this cutting-edge device. Headed by B. Montgomery Pettitt, Hugh Roy and Lillie Cranz Cullen Distinguished Professor in Chemistry, professor of computer science, physics, biology and biochemistry, and associate dean of research for the UH College of Natural Sciences and Mathematics, the IMD also recently received a $500,000 grant from the M.D. Anderson Foundation for construction and build-out costs associated with the Science & Engineering Research and Classroom Complex (SERCC).

A complex of three main structures, SERCC includes a five-story laboratory building with more than 150,000 square feet that will accommodate an estimated 40 research labs designed to support interaction. Among the buildings features are labs opening up to other labs with few walls to isolate them, as well as a dedicated, full-service clean room with a non-vibration floor, static-free environment and special air filters to remove virtually all dust particles. These new capabilities will allow for more collaborative, cross-disciplinary research among UH faculty in addition to benefiting local academic and industry partners who participate in the universitys research efforts.

Set to arrive by December, the $500,000 DNA sequencer made possible by the Cullen Foundation grant will help make UH a major player in genetic science by allowing the analysis not only of whole organisms but also of sampling with many organisms mixed together.

An organisms genome can contain the equivalent of millions of pages of data, Pettitt said. Breaking up the astonishingly complex genome into smaller chunks for study and then piecing it back together is an arduous task, but this high-powered sequencer can perform large, rapid scans of genetic material. Scientists can have the initial data in couple of days with this technology as opposed to years.

The sequencer will be only the second installation of its kind in Houston. There are plans for the UH sequencer to be used for stem cell research, Pettitt said.

Whether its zeroing in on the slightest hint of virus or bacteria from a mouth swab or constructing an ecological profile of an area by studying remnant DNA molecules that could be millions of years old to see what was there so long ago, the sequencers will help researchers in a number of groundbreaking endeavors.

It also will help scientists and students engaged in synthetic biology the creation of new functions and even life forms with synthesized genes.

Although life forms from scratch are still a ways off, the sequencer opens up new possibilities in genetic analysis that can lead to a profound change in how we do biological science, Pettitt said.

The remaining $250,000 from the Cullen Foundation gift will be used to finish outfitting research labs in SERCC. Similarly, the funds from the M.D. Anderson Foundation grant will be used to build out space on this research facilitys fourth floor. The grant will directly impact the completion of lab space to be used by the IMD, which is currently planned to be housed on the fourth floor of SERCC, allowing for more rapid and efficient collaboration to help advance the IMDs research most effectively.


'/>"/>

Contact: Lisa Merkl
lkmerkl@uh.edu
713-743-8192
University of Houston
Source:Eurekalert

Related medicine news :

1. Spirulina may be the next immune boost on the block
2. New drug helps boost cancer treatment
3. A boost to quit smoking
4. Hepatitis G May Boost HIV Survival
5. Drug Combinations May Boost Stroke Risk
6. Myth of female impotence created to boost sales
7. Reduced Fatigue Boosts Mental Health
8. Therapy Boosts Chemotherapy Effects
9. Need for Hepatitis Booster Questioned
10. Vasopressin Found To Boost Survival In Sudden Cardiac arrest
11. Exercising To Music Found To Boost Brain Power
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... , ... May 26, 2016 , ... ... clinical outcomes, hosted members and suppliers for its inaugural Member Conference at the ... their mission of elevating the operational health of America’s healthcare providers. , The ...
(Date:5/26/2016)... Washington, D.C. (PRWEB) , ... May 26, 2016 , ... ... the men and women who lost their lives in military battle for the country. ... discount cards in 2015 to provide more programs that empower independence for disabled military ...
(Date:5/26/2016)... ... May 26, 2016 , ... There are nearly 14.5 million people ... cancer survivors worldwide. On Sunday, June 5, 2016, communities around the world will gather ... Day®. , National Cancer Survivors Day® is an annual worldwide Celebration of Life ...
(Date:5/26/2016)... ... 2016 , ... Dr. James Maisel will present on “Macular ... on June 4, 2016, 1:30-3:30 pm at the Farmingdale Public Library. The presentation ... of New York , is a Board Certified ophthalmologist who completed his fellowship ...
(Date:5/26/2016)... ... May 26, 2016 , ... Memorial Day Weekend marks the unofficial ... is sharing tips to make sure your family and vehicle are ready to ... Council, there may be 439 deaths and an additional 50,500 serious injuries from motor ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... SAN FRANCISCO , May 27, 2016 ... biotechnology company focused on developing products for Regenerative Medicine, Neurology and ... Commissiong will be presenting at two upcoming investor conferences: ... Conference Center, 730 Third Avenue, New York City ... at 3:00pm Marcum MicroCap Conference   ...
(Date:5/26/2016)... May 26, 2016   Change Healthcare ... analytics, network solutions and technology-enabled services designed ... entered into a strategic channel partnership with ... software solutions and revenue cycle management services ... and rehabilitation clinics to optimize revenue, operational ...
(Date:5/25/2016)... and GERMANTOWN, Maryland , May 25, 2016 ... ; Frankfurt Prime Standard: QIA) today announced that the company ... Diagnostics GmbH to develop and commercialize predictive assays in oncology. ... as a marker to predict effectiveness of anthracycline treatment in ... "We are pleased to partner with Therawis, which developed the ...
Breaking Medicine Technology: