Navigation Links
'Half-Match' Marrow Transplants Help Some With Sickle Cell
Date:9/21/2012

n, along with a risk complications, including kidney failure, stroke, lung disease and blood clots. Many die of the disease before the age of 50.

Treatment is often centered around the use of narcotics for pain control, along with frequent blood transfusions and hospitalizations.

The good news: bone marrow transplants involving fully matched tissue donors have shown the potential to effect a cure in some patients.

The bad news: the vast majority of patients are black (with about one in every 400 blacks struck by the disease) and national donor registries are limited, leaving many to wait in vain for a donor match.

Brodsky and his team performed bone marrow transplants involving both fully matched donors (three cases) and half-matched donors (14 cases), among patients between 15 and 46 years of age.

Both full and partial donor matches were drawn from family members such as parents, children and/or siblings. And all patients underwent a comparatively "gentle" pre-procedure prep regimen of immuno-suppression, chemotherapy and radiation treatment, the study authors said.

The result: 11 of the 17 transplants were deemed "successful." And of these 11 patients, eight had undergone half-matched operations.

The study authors said there were no fatalities. They concluded that the half-matched approach appeared to produce a success rate greater than 50 percent.

Dr. Zora Rogers, clinical director of the General Hematology Program at the Children's Medical Center in Dallas, said that while the findings are "encouraging," they should be interpreted with caution.

"First of all," she said, "it's important to recognize that this half-matched procedure performed predominantly among adults was not as good as a fully matched transplant performed among children would be, where the cure rate exceeds 90 percent. In fact, when you look at the 11 patients they say got better, six of them, if you will, were really 'cured' of their disease
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Half-match bone marrow transplants wipe out sickle cell disease in selected patients
2. Fertilizing bone marrow helps answer why some cancers spread to bones
3. Markey receives $6.25 million to study deadly blood and bone marrow disease
4. HIV Drug May Prevent Bone Marrow Transplant Complication
5. HIV drug reduces graft-vs.-host disease in bone marrow transplant patients, Penn study shows
6. Clinical trial seeks to cure advanced Crohns disease using bone marrow transplant
7. Bone marrow transplant eliminates signs of HIV infection
8. HIV Undetectable in 2 Men After Bone Marrow Transplants: Study
9. New genetic clues to why most bone marrow transplant patients develop graft-versus-host disease
10. Lack of sleep affects bone health and bone marrow activity
11. First, Second Kidney Transplants Have Similar Success: Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Half-Match' Marrow Transplants Help Some With Sickle Cell
(Date:10/1/2014)... Lifeinsurance-policy.com has released a new blog post ... for smokers. , Smoking will always have a negative ... the best method to find affordable coverage. Insurance brokerage ... coverage. , Whole life insurance premiums will be ... the coverage is permanent, the initial rates are ...
(Date:10/1/2014)... ATLANTA (PRWEB) October 01, 2014 ... executive networking and relationship-marketing firm, announced today ... Security Executive® and Project of the Year ... decision makers representing organizations in financial services, ... include large-scale technology endeavors that address key ...
(Date:10/1/2014)... A new genetic finding from Duke Medicine suggests that ... depression might also be hard-wired to gain weight when ... disease. , An estimated 13 percent of people, all ... and knowing this could help them reduce heart disease ... and stress management. , "Genetic susceptibility, psychosocial stress and ...
(Date:10/1/2014)... Innovations announces the upcoming airing of Innovations with ... 20, 2014 at 7:30 a.m. EST/PT via Discovery Channel. ... scenes to learn about Break the Cycle’s comprehensive dating ... help and information Break the Cycle provides to teens ... abuse, how to navigate the legal system, and provides ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Anti Aging ... and skin rejuvenating destination of choice, is announcing a ... October through to December. , “We’re doing this because ... possible to our top skin clinic in Toronto,” says ... do so much at Anti Aging Clinic, including laser ...
Breaking Medicine News(10 mins):Health News:Affordable Whole Life Insurance Premiums for Smokers! 2Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 2Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 3Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 4Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 5Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 6Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 7Health News:Gene interacts with stress and leads to heart disease in some people 2Health News:Innovations to Explore Breakthroughs in Health and Wellness in Upcoming Episode Airing Monday, October 20, 2014 via Discovery Channel 2Health News:Anti Aging Clinic, the GTA’s Premier Provider of Anti Aging Treatments, Announces Deal on Units of Botox 2
... spokesman for Kirin Brewery Co. Ltd., Japan on Monday told ... antibody that can prevent and cure bird flu. ... in Tokyo. ,It is planning for a partnership ... will not be available immediately in the commercial market. ...
... that as many as 1,000 children in Venezuela may be ... have abandoned them, and they are forced to fend for ... that there are over 60 non-governmental organizations in the nation ... ensure that it does not spread, and contain it. ...
... A new research has revealed that happiness results ... The Psychological Bulletin of the American Psychological Association ... reinforcing positive emotions, which also motivates people to ... ,Dr. Sonja Lyubomirsky of the University ...
... the rounds in Saudi Arabia claiming that the batch number ... kingdom will harm the kidneys and liver has been confirmed ... provides relief from fever and pain. The Ministry has further ... about 23 days. The Pharmacists in the country’s Eastern Province ...
... has announced a ban on the anti-inflammatory drug Bextra, meant ... the drug were outweighed by the cardiovascular risks, including the ... an expert safety panel. ,The drug is ... prove to be fatal. Pfizer had earlier withdrawn the drug ...
... associated with several alleged miscarriages of justice has been ... decision has been hailed as one to preserve public ... officials in Saskatchewan have voted to curtail practicing privileges ... Smith. ,Smith had been granted temporary ...
Cached Medicine News:Health News:Happiness Plays An Important Role In Success 2
(Date:10/1/2014)... 2014  CVS Health is thanking its 26,000 pharmacists ... changing the way health care is delivered to increase ... retail pharmacies, mail service pharmacies and specialty pharmacies nationwide.  ... name to CVS Health to reflect our broader health ... needed to shape the future of health," said ...
(Date:9/30/2014)... - Protecting the health and safety of Canadians is our government,s ... powers and tools at its disposal to help ensure that the ... To that end, Health Canada ... Canada of all drug products from three plants ... , Apotex Pharmachem India Pvt Ltd , Apotex Research ...
(Date:9/30/2014)... BEDFORD, Mass. , Sept. 30, 2014  Hologic, ... Stephen MacMillan , Hologic,s President and Chief Executive ... Bell Ceremony on October 1, the first day of ... will discuss the Company,s campaign focused on the important ... system approved by the FDA as clinically superior to ...
Breaking Medicine Technology:CVS Health Thanking its Pharmacists during American Pharmacists Month for Helping People on Their Path to Better Health 2CVS Health Thanking its Pharmacists during American Pharmacists Month for Helping People on Their Path to Better Health 3Statement by the Honourable Rona Ambrose on the import ban of drug products from three plants in India 2Hologic to Kick Off National Breast Cancer Awareness Month at the October 1 NASDAQ Stock Market Opening Bell Ceremony 2Hologic to Kick Off National Breast Cancer Awareness Month at the October 1 NASDAQ Stock Market Opening Bell Ceremony 3
... , Knights of Columbus partners with Medishare to provide physical therapy and prosthetic limbs ... WASHINGTON , Aug. 4 ... aid of every Haitian child who lost a limb in the January earthquake that ... Many thousands more were seriously injured, including hundreds of children who lost arms and ...
... OvaGene Oncology Inc., a biotechnology ... DNA-based diagnostics for gynecologic cancer, is pleased to announce ... the Industry Collaboration Team (ICT) program.  By becoming a ... to building a strong partnership with the GOG research ...
Cached Medicine Technology:New Program Makes Prosthetics Available to All Haitian Children Who Lost Limbs in Earthquake 2OvaGene Oncology Joins The Gynecologic Oncology Group (GOG) Industry Collaboration Team to Advance Gynecologic Cancer Research 2OvaGene Oncology Joins The Gynecologic Oncology Group (GOG) Industry Collaboration Team to Advance Gynecologic Cancer Research 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: