Navigation Links
Hair samples from infants show exposure to anti-HIV drugs in the womb and during breast-feeding
Date:7/21/2012

In the study, the team took hair and blood samples from two groups of HIV-positive mothers, all of whom breast-fed their infants. For 45 mother/infant pairs, the mothers' antiretroviral regimens included a protease inhibitor, lopinavir, boosted by ritonavir, another antiretroviral medication. The other 64 mothers were on an efavirenz-based regimen.

Infants in the lopinavir group had levels of the drug in their hair that measured 87 percent of the levels found in their mothers' hair. The levels of ritonavir were about 45 percent of the levels found in their mothers' hair. When the researchers looked at the drug levels in the blood drawn from the mothers and infants at 12 weeks, they found the expected levels of lopinavir and ritonavir in the mothers, but none of either in the blood of the infants.

"The inability to find drug in the infants' blood at 12 weeks tells us that the lopinavir and ritonavir in their hair is not due to recent exposure, so breast-feeding did not transfer these drugs to the infants. Our conclusion is that the lopinavir and ritonavir were transferred to the babies in the womb, and lopinavir at quite a high level," said Gandhi.

In the efavirenz group, researchers found infant drug levels in hair samples that were about 40 percent of the levels found in their mothers. Additionally, they found that infants had levels in their blood that were about 15 percent of what was found in their mothers.

These findings indicate a moderate transfer of efavirenz both in the womb and during breastfeeding said Gandhi.

"Our findings, as we verify them, will have important implications. One, being able to measure drug exposures of fetuses in the womb and during breast-feeding can help us understand how to better protect infants from HIV transmission from HIV-positive mothers during pregnancy, birth and after birth. Antiretroviral medications are delivered prophylactically to HIV-positive mothers and newborns
'/>"/>

Contact: Jeff Sheehy
jsheehy@ari.ucsf.edu
415-597-8165
University of California - San Francisco
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. SomaLogic publishes proteomic biomarker analysis of lung cancer tissue samples
2. Depressed moms behavior may play role in infants sleep problems
3. Research shows efficacy of treatment model developed at Women & Infants
4. Low-Income Mothers May Overfeed Their Infants
5. Gut flora affects maturation of B cells in infants
6. Phthalates in PVC floors taken up by the body in infants
7. Disease that stunts infants growth traced to same gene that makes kids grow too fast
8. Infants cant distinguish between large and small groups
9. Women & Infants to participate in national effort to increase breastfeeding rates
10. Keep Infants Out of Sun and Heat, Experts Warn
11. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Hair samples from infants show exposure to anti-HIV drugs in the womb and during breast-feeding
(Date:7/30/2014)... 2014 Visitors to our region recognize ... to ensure its protection. Bob Kiesendahl, one of the ... the Delaware Highlands Conservancy for donations collected through participation ... donations add up fast, as visitors welcome the opportunity ... River Region. , The Kiesendahl family has owned Woodloch ...
(Date:7/30/2014)... "we caught it early" is possibly the best news ... cancer diagnosis. Combating cancer in its earliest stages, when ... the body, gives patients the best chances of survival. ... other forms of cancer are touted for saving lives ... screenings as a precautionary measure, especially for high-risk patients. ...
(Date:7/30/2014)... ... ... ... , UCLA researchers interviewed people with diverticulitis and confirmed that many suffer psychological and physical symptoms long after their ... UCLA team led by Dr. Brennan Spiegel interviewed patients in great detail about the symptoms they experience weeks, months or even years ...
(Date:7/30/2014)... (PRWEB) July 30, 2014 Over 630 ... Pinhole Surgical Technique®, the revolutionary minimally invasive treatment for ... considered by many of his peers to be the ... speaker at a recent Chao Pinhole Surgical Technique® training ... Dr. Shanelec is the recipient of the American Academy ...
(Date:7/30/2014)... 2014 The American Telemedicine Association ... Thad Cochran (R-MS) and Roger Wicker (R-MS) for ... coverage under Medicare, Medicaid and Federal Communications Commission ... Republicans, introduced the Telehealth Enhancement Act as S. ... H.R. 3306, introduced by Rep. Gregg Harper (R-MS) ...
Breaking Medicine News(10 mins):Health News:Pocono Mountain Resort Guests Contribute Over $8500 to Protect Land in 6 Short Months 2Health News:UK psychologist creates patient tool to assist with lung cancer screening decision 2Health News:UK psychologist creates patient tool to assist with lung cancer screening decision 3Health News:Diverticulitis patients reveal psychological, physical symptoms long after acute attacks 2Health News:Diverticulitis patients reveal psychological, physical symptoms long after acute attacks 3Health News:Periodontist Dr. Dennis Shanelec Comments On The Chao Pinhole Surgical Technique® Training Course 2Health News:ATA Applauds Senators’ Push for Federal Telemedicine Improvements 2
... the first to use a new tool to identify the ... of what these microscopic signatures or biomarkers should look like. ... Journal of Proteome Research, the advance could one day lead ... cancer as well as other diseases. , With many diseases, ...
... Provides Interventional Cardiologists with Enhanced ... Faster, More Precise Procedures, CHICAGO, March 31 According ... 1 killer,with an average of one death every 37 seconds. ... contributed to the surge of,Americans with cardiac issues. To address ...
... on Blue Cross ... EAGAN, Minn., March 31 In a peer-reviewed ... Cross and Blue,Shield of Minnesota (Blue Cross) reports that ... visits to the emergency room and,had an 11 percent ...
... medication, study finds , , MONDAY, March 31 (HealthDay News) ... diabetes drug, Amaryl, at slowing clogging of the arteries ... disease. , The Cleveland Clinic researchers behind the new ... diabetes medication has been shown to slow atherosclerosis, giving ...
... 2008 New data from a clinical trial ... patients living with type 2 diabetes, ACTOS® (pioglitazone ... arteries compared to glimepiride, and prevented progression compared ... PERISCOPE (Pioglitazone Effect on Regression of Intravascular Sonographic ...
... Considered by many in medical,marketing to be ... Ferdinand has joined,prominent Houston healthcare and sports marketing ... and Business Development., In her new role ... counsel for existing clients, and develop relationships,with potential ...
Cached Medicine News:Health News:Scientists: New technique identifies molecular 'biomarkers' for disease 2Health News:Scientists: New technique identifies molecular 'biomarkers' for disease 3Health News:See More, Do More: Siemens Highlights New Generation of Interventional Imaging Systems for Cardiology at ACC 2Health News:See More, Do More: Siemens Highlights New Generation of Interventional Imaging Systems for Cardiology at ACC 3Health News:See More, Do More: Siemens Highlights New Generation of Interventional Imaging Systems for Cardiology at ACC 4Health News:Blue Cross' Consumer-directed Health Plan - Options Blue - Members Not Sacrificing Health for the Sake of Saving Money 2Health News:Blue Cross' Consumer-directed Health Plan - Options Blue - Members Not Sacrificing Health for the Sake of Saving Money 3Health News:Diabetes Drug Slows Clogging of Arteries 2Health News:Diabetes Drug Slows Clogging of Arteries 3Health News:New data showed Actos prevented progression of atherosclerotic plaque volume in patients 2Health News:Medical Marketing Veteran Signs on as Director of Strategy and New Business Development at Active Imagination 2
(Date:7/30/2014)... 2014 /PRNewswire-iReach/ -- Transluminal Technologies LLC, a ... has announced today that they have received CE ... Device. Velox CD™ provides a safe and predictable ... procedures. The single size velox CD™ is indicated ... 5F to 8F.  Velox CD™ utilizes ...
(Date:7/30/2014)... , July 30, 2014 Reportlinker.com announces ... in its catalogue: mHealth and Home ... http://www.reportlinker.com/p0356852/mHealth-and-Home-Monitoring-–-6th-Edition.html Executive summary ... leading to better outcomes, decreased costs and improved ... mHealth solutions is still in an early stage, ...
(Date:7/30/2014)... --  Unique Pizza and Subs Corporation ("Unique," ... Delaware Corporation, is pleased to announce it has ... ("Larasan"), a nature-based pharmaceutical company that produces and distributes ... will work with Unique to help distribute its ... distribution network throughout China ...
Breaking Medicine Technology:Transluminal Technologies receives CE Mark approval for velox CD(TM) vascular closure device 2mHealth and Home Monitoring - 6th Edition 2mHealth and Home Monitoring - 6th Edition 3mHealth and Home Monitoring - 6th Edition 4mHealth and Home Monitoring - 6th Edition 5mHealth and Home Monitoring - 6th Edition 6mHealth and Home Monitoring - 6th Edition 7mHealth and Home Monitoring - 6th Edition 8mHealth and Home Monitoring - 6th Edition 9mHealth and Home Monitoring - 6th Edition 10mHealth and Home Monitoring - 6th Edition 11Unique Pizza and Subs Announces Asian Distribution Agreement with Larasan Pharmaceutical Corporation 2Unique Pizza and Subs Announces Asian Distribution Agreement with Larasan Pharmaceutical Corporation 3
... YORK, Oct. 7, 2011 Intellect Neurosciences, Inc. (OTCBB: ... clinical-stage pipeline, and multiple licenses with major pharmaceutical companies ... interview with Dr. Daniel Chain, Ph.D., Chairman and CEO ... Dr. Chain will be discussing the state ...
... Health Solutions, Inc. (NYSE: MHS ) today ... the Silver Award for Best Practices in Health Care ... healthcare accreditation organization, during the URAC 12th Annual Quality ... ) Medco,s program was selected as one ...
Cached Medicine Technology:Intellect Neurosciences CEO to be Featured on Wall Street Reporter 2Medco Wins 2011 URAC Award for Best Practices in Health Care Consumer Empowerment and Protection 2Medco Wins 2011 URAC Award for Best Practices in Health Care Consumer Empowerment and Protection 3
... Dermalinfusion is the only treatment ... a topical dermaceutical while exfoliating ... all skin types and addresses ... conditions including hyperpigmentation, acne, photodamage, ...
... With state-of-the-art, patented technology and the ... variety of conditions, the Solarus often ... depend on the Solaus for effective ... and you can also be confident ...
... Start or expand your aesthetic practice ... SR, the cost-effective system that's gentle, powerful ... seeking the exciting benefits of IPL Skin ... system promises to be an indispensable tool ...
... the perfect mix of powerful, versatile, and ... the Palomar StarLux® Pulsed Light and Laser ... one compact base unit so theres ... different treatments., You can choose among Laser, ...
Medicine Products: