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Haemacure's Human Fibrin Sealant Demonstrates Effectiveness in Skin Graft Fixation Proof-of-Concept Study for Burn Injury
Date:12/9/2008

rafts. There were no alterations to any of the other components of the fibrin sealant.

The use of the fibrin sealant between the skin graft and the wound bed interface was shown to (1) provide adhesive qualities allowing fixation of the graft without the use of staples or sutures, (2) seal the tissue bed layer, thereby inhibiting seroma or hematoma formation without compromising the healing process, and (3) likely provide more even healing, resulting in a higher percentage of graft take with a more acceptable cosmetic outcome than using mechanical fixation.

Previous preclinical studies have demonstrated the effectiveness of Haemacure's fibrin sealant hemostasis formulation in preventing the formation of post-surgical adhesions. The ability to utilize the fibrin sealant hemostasis formulation for the additional indications of adhesion prevention and skin graft fixation is anticipated to reduce manufacturing and clinical risks and to significantly shorten time-to market, by as much as three to five years. Haemacure plans on conducting additional studies to support and confirm these findings.

About Haemacure

Haemacure Corporation is a specialty biotherapeutics company developing high-value human plasma-derived protein products for commercialization. Haemacure's research and development effort is driven by its proprietary plasma protein extraction technology to develop next-generation products, including surgical haemostats. Haemacure's lead product candidate, Hemaseel(R)HMN, is a fibrin sealant to enter pivotal Phase II/Phase III clinical trials during the first half of calendar 2009. Haemacure's second product candidate is thrombin, a component of its fibrin sealant, now in preclinical stage. Follow-on development will focus on the use of fibrin sealant in aesthetics, adhesion prevention, combination with biomaterials, drug delivery, regenerative medecine, skin graft fixation for burn injuries, and wound he
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SOURCE Haemacure Corporation
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