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Haemacure Discloses Positive Results of a preclinical study of its fibrin sealant in adhesion prevention and opens a new opportunity in a market with a significant unmet medical need
Date:4/10/2008

HAE:TSX

MONTREAL, April 10 /PRNewswire-FirstCall/ - Haemacure Corporation (TSX : HAE), a Montreal-based specialty bio-therapeutics company developing high-value human plasma-derived protein products for commercialization, disclosed today the results of a preclinical study it recently conducted on the use of its proprietary lead product candidate, the human fibrin sealant Hemaseel(R)HMN, in preventing the formation of post-surgical adhesions.

The study was conducted on 16 rabbits that underwent open gynaecologic surgery in a uterine horn model. In preclinical testing, Hameacure's fibrin sealant was found to be significantly superior to the control group in preventing the formation of post-surgical tissue adhesion. It was also found to be superior to historical data disclosed in published literature for GYNECARE INTERCEED(TM)(TC7) Absorbable Adhesion Barrier, marketed by Ethicon, Inc.

These preclinical results are strategically significant as Haemacure's current fibrin sealant haemostasis formulation was used in this study. Initial analysis indicates that no change in the formulation or the manufacturing of Haemacure's fibrin sealant will be required to pursue an adhesion prevention indication. The safety and manufacturing information applicable to an IND to conduct adhesion prevention trials using Haemacure's fibrin sealant is identical to the information that will be included in the IND amendment to be filed later this year for the haemostasis indication. It is likely that adhesion prevention-specific preclinical data, clinical protocols and programs will also be required.

The use of Haemacure's current fibrin sealant haemostasis formulation for adhesion prevention could significantly accelerate time to market for this indication, by three to five years. This reduced timeframe accelerates Haemacure's ability to address a significant unmet medical need with an additional indication for its fibrin sealan
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SOURCE Haemacure Corporation
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