Navigation Links
HRT therapy appears to increase risk of hospitalization from severe asthma attacks

Amsterdam, The Netherlands: Women taking postmenopausal hormone replacement therapy (HRT) may have an increased risk of severe asthma attacks requiring hospitalisation, scientists warn.

A new study, which will be presented today (27 September 2011) at the European Respiratory Society's Annual Congress in Amsterdam, adds to the debate over the health effects of the drug which helps women through the menopause.

Previous studies have found a link between asthma and HRT, but this is the first to suggest that the drug can lead to severe exacerbations of asthma, which could lead to hospitalisation.

Researchers Klaus Bnnelykke from COPSAC (the COpenhagen Prospective Studies on Asthma in Childhood) at the Danish Pediatric Asthma Center and Zorana Jovanovic Andersen from the Danish Cancer Society recorded the intake of HRT in 23,138 women from the Danish Diet, Cancer and Health Cohort. They also denoted incidence of asthma hospitalisations and obtained information on participants' smoking status, occupational exposure, body mass index and whether or not they had undergone a hysterectomy to account for other factors relating to asthma incidence.

The results showed that using HRT was positively associated with asthma hospitalisations, as women were 1.3-times more likely to be admitted to hospital for an exacerbation if they were taking the drug. The risk increased the longer HRT was used and women taking the drug for longer than 10 yrs were 1.5-times more likely to require hospital treatment for asthma.

These results were also found when taking into account other conflicting factors which could lead to a severe asthma exacerbation.

Dr Klaus Bnnelykke, from COPSAC, said: "Previous research has suggested a link between asthma and female sex hormones, especially HRT. Our findings not only confirm this link, but also extend this to severe asthma exacerbations. We still need the final proof from randomised trials, but we believe that the suspicion is now so strong that it should be brought to the attention of clinicians. If a patient develops asthma or has a severe worsening of symptoms after taking HRT, they may need to stop hormone therapy altogether."


Contact: Lauren Anderson
European Lung Foundation

Related medicine news :

1. New hope for advanced post-menopausal breast cancer patients resistant to hormonal therapy
2. Radiotherapy between or during chemotherapy cycles reduces risk of breast cancer recurrence
3. Infusing chemotherapy into the liver gives extra months of disease-free life in melanoma patients
4. New Test Predicts Risk for Impotence After Prostate Cancer Therapy
5. Adding Psychotherapy to Meds Helps Kids With OCD
6. Benefits of radionuclide therapy for neuroendocrine tumors
7. UNC scientist proves potential of new nanoparticle design for cancer therapy
8. UCSF study identifies weakness in heart attack therapy
9. Moffitt researchers find possible key to preventing chemotherapy resistance in ovarian cancer
10. Tailored Hepatitis C Therapy May Cut Treatment Time in Half
11. Fish oil reduces effectiveness of chemotherapy
Post Your Comments:
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced ... feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as a ... has released tools for healthy coping following a traumatic event. , Trauma sufferers tend ...
(Date:6/24/2016)... ... 24, 2016 , ... The Pulmonary Hypertension Association (PHA) learned ... receive two significant new grants to support its work to advance research and ... by recognizing patients, medical professionals and scientists for their work in fighting pulmonary ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Comfort ... the American Cancer Society and the Road To Recovery® program to drive cancer patients ... seniors and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... today at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra ... authored journal articles published in Emergency Medicine Practice and Pediatric Emergency ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... feeding the Frederick area economy by obtaining investment capital for emerging technology companies. ... 2½ years that have already resulted in more than a million dollars of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016   Bay Area Lyme Foundation , ... Center for Tick Borne Illness , Harvard Medical ... Hacking Medicine, University of California, Berkeley, and the ... five finalists of Lyme Innovation , the ... 100 scientists, clinicians, researchers, entrepreneurs, and investors from ...
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical Systems ... "Company"), which develops, markets and sells medical devices and ... , signed a strategic cooperation agreement with Hongyuan Supply ... Supply Chain") on June 20, 2016, to develop Dehaier,s ... strategic cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s ...
(Date:6/24/2016)... 24, 2016   Pulmatrix, Inc ., (NASDAQ: ... inhaled drugs, announced today that it was added to ... its comprehensive set of U.S. and global equity ... an important milestone for Pulmatrix," said Chief Executive Officer ... of our progress in developing drugs for crucial unmet ...
Breaking Medicine Technology: