Navigation Links
HPV-positive head and neck cancer patients fare better than HPV-negative patients
Date:2/12/2008

Head and neck cancer patients with HPV-positive tumors tend to survive longer and are more responsive to treatment compared with patients with HPV-negative tumors, according to a study published online February 12 in the Journal of the National Cancer Institute.

Human papillomavirus has been shown to be involved in the development of some head and neck cancers, particularly cancers of the upper throat, or oropharynx. Retrospective studies suggest that patients with HPV-positive tumors generally have a better prognosis than those patients with HPV-negative tumors, but these findings must be confirmed in clinical trials.

To examine the association between HPV infection and cancer prognosis, Maura Gillison, M.D., Ph.D., of Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University in Baltimore and colleagues followed 96 patients with stage III or IV cancer of the oropharynx or larynx (voicebox). All of the patients were enrolled in the same phase II clinical trial and received the same treatment. The researchers collected data on the patients response to treatment and their survival times, as well as whether their tumors were HPV-positive or -negative.

Patients with HPV-positive tumors had higher response rates after chemoradiation therapy, compared to patients with HPV-negative tumors (84 percent vs. 57 percent), and their two-year overall survival rates were also higher (95 percent vs. 62 percent).

Our data suggest that the risks and benefits oftherapies should be considered separately for HPV-positive and -negative patients, the authors write.


'/>"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
Source:Eurekalert

1

GOOD

Page: 1

Related medicine news :

1. HPV-Positive Head and Neck Cancers Fare Better
2. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
3. Survival differences by race most apparent in advanced stages of breast cancer
4. MRI finds breast cancer before it becomes dangerous
5. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
6. Pathway links inflammation, angiogenesis and breast cancer
7. Radiologists encouraged to look beyond cancer for clinically unseen diseases
8. Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death
9. Immune deficiency linked to a type of eye cancer
10. Drop in breast cancer incidence linked to hormone use, not mammograms
11. Breast cancer prevention practices vary across Canada
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/19/2013)... According to a May 14th, 2013 Harper’s Bazaar ... about the appearance of certain areas of the body. ... fail to tone and tighten these areas. The report details ... get the firmest body possible (article: goo.gl/tPiha). , ... Simon Ourian, Medical Director of Epione Beverly Hills. “I don’t ...
(Date:5/19/2013)... York (PRWEB) May 19, 2013 ... a federal litigation now underway in U.S. District Court, ... Management Order dated May 3rd, the Court has modified ... Pool to eight cases rather than four. The next ... for Thursday, May 23rd. (In re: Actos Product Liability ...
(Date:5/19/2013)... 19, 2013 6Webs.com is the leader ... Homeowners who are considering an alarm system can do ... nation's leading security system providers online at 6Webs.com. Just ... best DIY home security system companies, 6Webs.com currently ... dozens of home security companies before ranking the home ...
(Date:5/19/2013)... Americans live closer to their dogs than ... Medical Association (AVMA) U.S. Pet Ownership and Demographics Sourcebook, ... dog a member of the family, up from the ... years earlier. , According to the American Pet Products ... dedicated to pets has increased every year without interruption, ...
(Date:5/19/2013)... Los Angeles (PRWEB) May 19, 2013 Yeast ... infections can appear in sensitive areas of the human body. ... by Yeastrol. This new formula provides a unique method of ... This new spray solution is now provided to men and ... Yeast is naturally absorbed in the body through food and ...
Breaking Medicine News(10 mins):Health News:Body Firming – The Hottest Treatments Available 2Health News:Actos Lawyers at Bernstein Liebhard LLP Note Issuance of New Case Management Order in Federal Actos Bladder Cancer Litigation 2Health News:Actos Lawyers at Bernstein Liebhard LLP Note Issuance of New Case Management Order in Federal Actos Bladder Cancer Litigation 3Health News:Top Rated DIY Home Security System Companies Published by 6Webs.com 2Health News:Dogs Becoming Part of the Family: Dog Bite Injuries Decreasing 2Health News:Dogs Becoming Part of the Family: Dog Bite Injuries Decreasing 3Health News:A Safe & Homeopathic Yeast Infection Relief by Yeastrol Now Available at HealthCareSupplementz.com with Massive Discount 2
... help the human brain to enhance memories like the ability ... that previous studies had established the benefits of sleep for ... sequences on a keyboard. It was explained that the new ... recalling the facts for a test, where in the brain's ...
... assess obesity rather than body mass index (BMI), the huge ... example, is cut in half, and white men are found ... men. ,While the medical literature has long showed ... of fatness than BMI, most social science researchers still use ...
... of the 10-month-old conjoined twins, who were separated last week ... place on Thursday, was hailed as a "miracle" by the ... Hu Jingxuan, was unable to tolerate the stress. ... the twins, Chen Jingni, was in a stable condition, while ...
... fast lane, business competition, deadlines and staff constraints stresses ... family, books and holidays //for relief, says a new ... leaders coping with work pressure suffers more from mental ... of Commerce and Industry of India) Business Barometer (ABB) ...
... has caused Australian businesses stockpile anti-viral drugs and face masks. ... have regular meetings regularly Public companies such as Bluescope Steel ... planning project manager. ,Expanded computer networks to enable ... outbreak have been included in the preparations against bird flu. ...
... warned people against consuming uncooked oysters imported from Korea. ... to be cooked before consuming. The warning is mainly ... which causes a gastrointestinal illness. ,In ... 1kg bags and labeled according to the current import ...
Cached Medicine News:Health News:Sleep Essential For A Strong Memory 2Health News:Family, Books Best Stress-busters for Indian CEOs 2Health News:Australian Businesses Prepare for Outbreak of Bird Flu 2
(Date:5/17/2013)... , May 17, 2013 Sinovac Biotech Ltd. ... in China , today announced that it ... ended March 31, 2013, before market on Tuesday, May 28, ... May 28, 2013, at 8:00 a.m. EDT (May 28, 2013 ... financial results and provide an update on recent corporate developments. ...
(Date:5/16/2013)... , May 16, 2013  PTC Therapeutics, Inc., ... on Form S-1 with the U.S. Securities and Exchange ... of its common stock. The number of shares to ... have not been determined. (Logo:  http://photos.prnewswire.com/prnh/20010919/PTCLOGO ... are acting as joint book-running managers for the offering. ...
(Date:5/16/2013)... WALTHAM, Mass. , May 16, 2013  Alere Inc. ... individuals to take charge of their health at home through ... a cash dividend of $3.00 per share on its Series ... payable on July 15, 2013 to holders of record of ... 1, 2013.  Such payment will cover the amount ...
Breaking Medicine Technology:Sinovac to Host Conference Call to Report First Quarter 2013 Unaudited Financial Results 2Sinovac to Host Conference Call to Report First Quarter 2013 Unaudited Financial Results 3PTC Therapeutics, Inc. Files Registration Statement for Proposed Initial Public Offering 2
... Magnetically Guided Nanoparticles May Deliver Treatments to Human,Organs -, ... and tiny iron-bearing particles to drive healthy cells to,targeted ... may lead to,a new method of delivering cells and ... (Photo: http://www.newscom.com/cgi-bin/prnh/20080107/DC10966 ), The study team, ...
... 7 Fovea Pharmaceuticals SA, which, last,December ... financing, today announced that,its product, Recombinant human ... as Orphan Medicinal Product from the,European Commission, ... for the Evaluation of Medicinal Products (EMEA) ...
Cached Medicine Technology:Researchers Use Magnetism to Target Cells to Animal Arteries 2Researchers Use Magnetism to Target Cells to Animal Arteries 3Researchers Use Magnetism to Target Cells to Animal Arteries 4Fovea Pharmaceuticals Receives Orphan Drug Designation from EC for RdCVF for the Treatment of Retinitis Pigmentosa 2Fovea Pharmaceuticals Receives Orphan Drug Designation from EC for RdCVF for the Treatment of Retinitis Pigmentosa 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: