Navigation Links
HPV infection highly prevalent among organ transplant recipients
Date:7/12/2011

A new study published in the American Journal of Transplantation reveals an association between the human papillomavirus (betaPV) infection and cutaneous squamous cell carcinoma (SCC) in organ transplant recipients.

HPV is known to cause cervical cancer and SCC in the anogenital area and also plays a role in some forms of head and neck cancer. SCC skin cancer is increasing in incidence worldwide and the risk is particularly high in immunosuppressed individuals such as organ transplant recipients in whom rates are 100 times those of the general population.

Researchers led by Jan Nico Bouwes Bavinck and Mariet Feltkamp of Leiden University Medical Center, studied a total of 210 organ transplant recipients with previous SCC and 394 controls without skin cancer. They used cutting-edge technologies to assess the presence of 25 betaPV types in plucked eyebrow hairs with simultaneous detection of antibodies to these viruses in blood.

Results show that BetaPV infection is highly prevalent in organ transplant recipients; 94% of patients without skin cancers carried DNA in eyebrow hairs and 97% in those with a history of skin cancer. Furthermore, concordant presence of DNA and antibodies to the same beta HPV type is associated with increased risk for SCC skin cancer.

"Carriage of beta HPV types (a particular skin group of HPV viruses) is extremely common in immunosuppressed individuals," Feltkamp notes. "Our research findings help to provide a clearer picture of the specific HPV types that may play a part in causing SCC which ultimately may lead to novel preventative or therapeutic interventions."


'/>"/>

Contact: Amy Molnar
healthnews@wiley.com
Wiley-Blackwell
Source:Eurekalert

Page: 1

Related medicine news :

1. DNDi expands activities to neglected patient needs in the field of helminth infections
2. Copper reduces infection risk by more than 40 percent
3. Cotton Swabs Help Prevent Surgical Site Infections: Study
4. Team approach reduces urinary tract infections in rehab patients
5. Intensive, hands-on effort reduces bloodstream infections in critically ill patients
6. Innovative duct tape strategy saves hospitals time, money; improves infection prevention
7. Noisy ORs Linked to Raised Risk of Surgical Site Infection
8. Noisy operations associated with increased infections after surgery
9. 1 in 4 new HIV infections in Ontario are among women: Study
10. New American Chemical Society podcast: Fast test to diagnose MRSA infections
11. Obese People at Higher Risk of Infection After Colon Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/17/2017)... ... February 17, 2017 , ... The Alliance ... change designed to further positively impact the health and wellness of our community ... considered it our duty to seriously consider releasing our assets beyond our 5% ...
(Date:2/17/2017)... , ... February 17, 2017 , ... ... to Prevent a Warning Letter, **An FDAnews Webinar**, Feb. 23, 2017 — 1:30 ... manufacturers distinguish between corrective action (CA) and preventive action (PA)? , The methods ...
(Date:2/17/2017)... ... February 17, 2017 , ... ... executives and focusing on all facets of clinical trial planning and management. Pharmica ... patient engagement, and more. In addition, attendees stopping by Pharmica’s booth were able ...
(Date:2/17/2017)... ... February 17, 2017 , ... ... financial planning assistance to families and business owners in and around the Hampton ... drive to help prevent all forms of domestic violence. , There are multiple ...
(Date:2/16/2017)... ... February 17, 2017 , ... ... planning services to families and entrepreneurs in the Birmingham area, is announcing an ... who needs assistance with her medically challenged son, Anius. , Anius is medically ...
Breaking Medicine News(10 mins):
(Date:2/16/2017)... -- Absorption Systems, a global leader in nonclinical testing ... announce that its Chief Operating Officer, Sid Bhoopathy ... the 2017 Executive Management Award. The award is sponsored ... for their creative management vision, leadership philosophy, innovative strategy ... is on March 8, 2017 at the Ballroom at ...
(Date:2/16/2017)... DaVita Inc. (NYSE: DVA ) today ... 2016. Net income attributable to DaVita Inc. ... $158 million, or $0.80 per share and $880 million, or ... attributable to DaVita Inc. for the quarter and year ended ... $192 million, or $0.98 per share, and $789 million, or ...
(Date:2/16/2017)... Feb. 16, 2017 The Lockwood Group (Lockwood), a ... Place to Work in Connecticut list ... third year in a row that Lockwood has been in ... earn the number-two spot in 2017. The award recognizes companies ... The winners were determined through a survey conducted by The ...
Breaking Medicine Technology: