Navigation Links
HPV eradicated by AHCC supplement, preclinical study suggests
Date:3/23/2014

(March 23, 2014, Beaverton, OR) Treating cervical cancer cells with AHCC led to the eradication of HPV, human papillomavirus, as well as a decrease in the rate of tumor growth in-vitro and in-vivo, in research presented at the Society of Gynecological Oncology 45th Annual Meeting on Women's Cancer in Tampa, Florida. The study was led by Dr. Judith A. Smith, Pharm.D., at the University of Texas Health Science Center (UTHealth) Medical School at Houston.

In the study cervical cancer cells were treated with AHCC and incubated for 72 hours with sampling every 24 hours. The study was then repeated in two orthotopic mouse models, one HPV positive and other HPV negative control. The HPV expression was eradicated with once daily AHCC dosing for 90 days with durable response after 30 day observation off treatment. Dr. Smith then repeated the study to confirm findings and added sampling for correlative testing of immune markers to determine the mechanism by which AHCC eradicates the HPV virus.

These data suggest AHCC can eliminate HPV infections and may have a role in the prevention of HPV-related cancers. A confirmatory pilot study in HPV+ women is underway at UTHealth Women's Center.

"The results of this study were very encouraging," said Dr. Smith, Associate Professor at the UTHealth Medical School. "This study, initiated in 2008, shows that by itself AHCC has the potential to treat the HPV infection," she said. Smith's previous study evaluated AHCC integration with common chemotherapy agents used for the treatment of ovarian cancer, to screen for potential drug interactions and improvement in activity.

AHCC works as an immunotherapy, which is a treatment that uses a body's own immune system to help fight disease. Human and in-vivo studies have shown that AHCC increases the number and/or activity of Natural Killer (NK) cells, dendritic cells, and cytokines, which enable the body to effectively respond to infections and block the proliferation of tumors. http://ahccresearch.com/index.html

HPV (human papilloma virus) is the most common sexually transmitted virus in the United States. Up to 70% of sexually active adults will acquire HPV at some point in their lives. Human papillomavirus DNA has been detected in 99.7% of cervical cancer biopsies, yielding the largest causative relationship of any cancer. (1) According to the CDC several other types of cancer are also HPV related, including: 95% of anal cancer; 60% of oropharyngeal cancer; 65% of vaginal cancer; 50% of vulvar cancer; and 35% of penile cancer.

"I was intrigued by research presented at the annual AHCC symposium in Sapporo (2) showing the immune modulating effect of AHCC on other rare infections, and was eager to study the possibilities in treating the HPV infection associated with cervical cancer," said Dr. Smith.

"AHCC is a common, well tolerated nutritional supplement that has been used for decades in Japan, I am very excited to be pursuing a nutritional approach to trying to find a treatment for HPV infections," said Dr. Smith, whose research is on drug development for gynecologic cancers and conditions with a specific focus on drug interactions/drug resistance and integration of herbal and nutritional supplements for treatment of cancer.

"We had previously demonstrated an antiretroviral regimen that successfully eradicated the HPV infection but wanted to develop a more benign protocol, since these medications have a number of side effects," Dr. Smith continued.


'/>"/>

Contact: John Carney or Julie McQuain
JMPRmedia@aol.com
212-477-0472
JMPR Associates, Inc.
Source:Eurekalert

Related medicine news :

1. New L-Carnitine and Green Coffee Bean Supplement, L-Carnitine Plus Now Available
2. Nutralife Health Products Inc. Announces Launch of New Website for its Revolutionary Joint Supplement, JointRite
3. Successful Dieter Starts Gold Coast With Revolutionary Weight Loss Supplement, Garcinia Cambogia
4. PhenObestin 37.5, a Pharmaceutical Grade Dietary Supplement, Urges Dieters to Lose Weight Without Experiencing Harmful Side Effects
5. LifeBotanica's Groundbreaking Anti-Aging Supplement, AGE DEFYING, Introduced
6. HyperGH 14x, the Natural Supplement, is Finally Available at NaturalHerbalz.net to Boost Muscle Growth Naturally and Safely
7. Preclinical data support ongoing clinical trials testing IDO inhibitors as a treatment for cancer
8. Genetically-engineered preclinical models predict pharmacodynamic response
9. Preclinical study identifies master proto-oncogene that regulates ovarian cancer metastasis
10. Preclinical tests shows agent stops slippery proteins from binding, causing Ewing sarcoma
11. Mayo Clinic: Preclinical tests may lead to new approach to treat CNS lymphoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills is proud ... and unique items from across the nation, this holiday-themed event will raise funds and ... the VNA. The boutique will be open Saturday, November 4 (10:00 a.m. – ...
(Date:10/13/2017)... ... , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has ... least understood books in the Holy Scriptures, Revelation. The Book of Revelation paints a ... centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins says that ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains ... possible to save lost souls in the Philippines. “The Journey: From the Mountains to ... dedicated teacher of the Bible. She has taught all ages and currently teaches a ...
(Date:10/12/2017)... San Francisco, CA (PRWEB) , ... October 12, ... ... and Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus ... sleep apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), one ... an innovative new design of the shoulder pad. The shoulder pad provides optimal ... controlling your pain while using cold therapy. By utilizing ice and water that is ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... the Centers for Disease Control and Prevention (CDC), influenza vaccination should ... helping communities across Massachusetts , Connecticut ... shots through the end of the month. *Some exclusions apply ... ... is by the end of October, according to the Centers for Disease ...
(Date:10/2/2017)... , Oct. 2, 2017  AllianceRx Walgreens Prime, the ... by Walgreens and pharmacy benefit manager Prime Therapeutics LLC ... brand, which included the unveiling of new signage at ... as well as at a few other company-owned facilities ... brand to patients, some of whom will begin to ...
(Date:9/28/2017)... , Sept. 28, 2017 Cohen Veterans ... advance the use of wearable and home sensors for ... disorders. Early Signal Foundation, a nonprofit organization focused on ... will provide an affordable analytical system to record and ... ...
Breaking Medicine Technology: