Navigation Links
HPV-associated cancer incidence rates point to needed efforts to increase HPV vaccination coverage

Despite the decline in cancer death rates in the U.S., there is an increase in incidence rates for cancers associated with human papillomavirus (HPV) infection and more efforts are needed to increase HPV vaccination coverage levels to prevent the occurrence of these cancers in the future according to a study published January 7 in the Journal of the National Cancer Institute.

The American Cancer Society (ACS), the Centers for Disease Control and Prevention (CDC), the National Cancer Institute (NCI), and the North American Association of Central Cancer Registries (NAACCR) annually provide updates on trends in cancer incidence and death rates in the United States. This year's report highlighted trends in incidence rates for HPV associated cancers and HPV vaccination coverage levels. Two HPV vaccines (bivalent and quadrivalent) have been shown to protect against most cervical cancers in women and one vaccine (quadrivalent) also protects against genital warts and cancers of the anus, vagina and vulva. There is no data available on vaccine efficacy for prevention HPV-associated cancers of the oropharynx.

In order to assess trends in HPV-associated cancer incidence rates and HPV vaccination coverage levels, Ahmedin Jemal, D.V.M., Ph.D., Surveillance Research Program, American Cancer Society, Atlanta, GA., and colleagues examined cancer incidence data reported by the CDC, and NCI, through NAACCR, as well as cancer mortality data from the CDC. The researchers determined trends in age-standardized incidence and death rates for all cancers combined and for the leading cancers among men and women, while HPV vaccination coverage levels during 2008 and 2010 and the prevalence of Papanicolaou (Pap) testing during 2010 were obtained from national surveys.

During 2000-2009, the researchers found that overall cancer death rates in the U.S. continue to decrease (including for lung, colorectal, female breast, and prostate cancers), but that death rates have increased for cancers of the liver, pancreas, uterine corpus, and melanoma of the skin among males. The incidence rates for these cancers continued to increase as well, including for some cancers associated with HPV infection. Nationally, 32.0% of females aged 13-17 years had received three doses of the HPV vaccine in 2010 showing the necessity for increased efforts to increase HPV vaccination coverage. "Continued monitoring of incidence and mortality trends for all cancers is warranted to inform cancer prevention and control policies and programs," the authors conclude.

In an accompanying editorial, Marc Brisson, Ph.D., Centre de recherche du CHU de Qubec, Hpital Saint-Sacrement, Qubec, Canada, and colleagues write that HPV vaccination efforts should be focused on females because it's been predicted to be the most effective way to ensure population-level vaccine effectiveness. "Finding ways to increasing vaccine uptake is a key priority for HPV-related public health research in the United States."


Contact: Zachary Rathner
Journal of the National Cancer Institute

Related medicine news :

1. Costly breast cancer screenings dont add up to better outcomes
2. Centralization to fewer surgeons results in better survival after esophageal cancer surgery
3. Some HPV-Linked Cancers Rising in U.S.: Report
4. Costly Breast Cancer Screenings May Not Help Seniors: Study
5. US Drug Watchdog Now Urges Any Diabetic Who Used the Diabetes Drug Actos and Now Have Been Diagnosed with Bladder Cancer to Call The Johnson Law Group-ASAP
6. Cancer Genome Institute at Fox Chase among first to offer clinical blueprint of cancer genes
7. Ovarian cancer stem cell study puts targeted therapies within reach
8. How prostate cancer therapies compare by cost and effectiveness
9. Mayo Clinic researchers find new molecule to target in pancreatic cancer treatment
10. Scientists discover how deadly skin cancer spreads into other parts of the body
11. Some Complain of Shorter Penis After Prostate Cancer Treatment: Study
Post Your Comments:
(Date:11/27/2015)... ... 2015 , ... The moment you stop improving is the ... the needs of advisers and clients but going above and beyond to find ... service. However, there's always room for improvement, which is why the entire Consulting ...
(Date:11/27/2015)... ... 27, 2015 , ... CBD College is proud to announce that ... awarded accreditation to its Diagnostic Medical Sonography program. CBD College is honored to join ... twelve colleges and universities in the state of California make the cut. CBD College ...
(Date:11/27/2015)... Rosa, CA (PRWEB) , ... November 27, 2015 , ... ... Northern California Medical Associates, Inc. and Dr. Tucker Bierbaum with Emergency Medicine at ... meeting. They observed that both STEMI and Sepsis conditions present in similar ways and ...
(Date:11/27/2015)... ... 2015 , ... Indosoft Inc., developer and distributor of the ... LTS (Long Term Support) into its Q-Suite 5.10 product line. , Making the ... a version of Asterisk that will receive not only security fixes, but feature ...
(Date:11/26/2015)... ... , ... Inevitably when people think Thanksgiving, they also think Holiday sales and ... Friday and Cyber Monday massage chair sales to receive the best pricing ... to find the best massage chair deals, they can see all of the coupons ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... , Nov. 27, 2015 Research and Markets ... "Global Intrauterine Devices Market 2015-2019" report to ... --> In this report, the author the present ... market for 2015-2019. To calculate the market size, the ... type of products: Hormonal IUDs and copper IUDs. The ...
(Date:11/26/2015)... Países Bajos, November 26, 2015 ... fotodinámica de Bremachlorin para el cáncer avanzado.   ... con la terapia fotodinámica de Bremachlorin para el cáncer ... enfoque combina la inmunoterapia con la terapia fotodinámica de ... Clinical Cancer Research . --> Clinical Cancer ...
(Date:11/26/2015)... November 26, 2015 ... nieuwe aanpak combineert immunotherapie met Bremachlorin-photodynamische therapie ... ) --> ... (Photo: ) ... Medisch Centrum (LUMC) blijkt ...
Breaking Medicine Technology: