Navigation Links
HPV DNA testing over 50 percent more sensitive than cytology testing
Date:7/8/2010

HPV DNA testing for precancers and cervical cancers is over 50 per cent more sensitive than cytology testing for the same conditions a community-based study in Mexico has revealed. Results of the largest HPV DNA primary screening study ever to be performed in a Latin American country point to the readiness of HPV DNA testing for large-scale implementation in Mexico and are published online today (8 July 2010) in Cancer, Causes and Controls.

Attila Lorincz, Professor of Molecular Epidemiology at Barts and The London School of Medicine and Dentistry is among researchers behind the study which involved over 50,000 women, aged 20-70, undergoing routine cytology and high risk (HR) HPV DNA testing. All those who tested positive through cytology were referred to colposcopy, while the HPV DNA positive women were followed by repeat HPV DNA testing with colposcopy if they were repeat positive in one year. The study is a pilot implementation to determine the real world performance of routine HPV DNA testing and routine cytology testing in the Mexican IMSS health insurance system.

In women who were both cytology and HPV DNA positive the rate of precancer or cancer was 19.7 per cent whereas the corresponding rate in women who were positive by cytology alone was only 3 per cent. In women who were positive twice for HR HPV DNA (regarded as HPV persistent) the rate of precancer and/or cancers was 11.7 per cent.

Overall the sensitivity of HPV DNA testing for precancers and cervical cancers was 93.3 per cent versus only 40 per cent for cytology testing.

Professor Lorincz said of the results: "The data confirms that HR-HPV DNA testing is much more sensitive than cytology and that HPV testing also identifies women with high risk of serious cervical disease in an efficient and medically acceptable manner.

"The advantage of this new cervical cancer screening approach is that women who are HPV DNA positive can be quickly referred to colposcopy (within one year), thus catching the vast majority of the precancers and cancers. In contrast women who are HPV DNA negative can be safely made subject to much longer screening intervals (5 to 10 years) saving considerable costs for the Mexican health system. "


'/>"/>

Contact: Alex Fernandes
a.fernandes@qmul.ac.uk
44-207-882-7910
Queen Mary, University of London
Source:Eurekalert

Related medicine news :

1. New testing method hints at garlics cancer-fighting potential
2. Twenty-Five Years of HIV Blood Testing Helped to Positively Transform Global Health Crisis
3. Christine P. Carrington, President of NurseTesting Creative Solutions, Inducted into Cambridge Who's Who
4. New Allergy Testing Available for Patients Allergic to Penicillin: Determining the Presence of Penicillin Allergy is Essential to Patient Care
5. Breast Cancer Patients Often Confused by Genomic Testing
6. Study Results Validate Shape-HF as Simplified, Portable Cardiopulmonary Exercise Testing System
7. San Francisco AIDS Foundation Introduces HIV Testing to Sixth Street
8. Phybridge Inc. Joins the Cisco Developer Network and Completes Cisco Interoperability Verification Testing
9. UAB testing software program to improve safety among older drivers
10. Study Published by Circulation Heart Failure Reinforces Science Behind Shape-HF Cardiopulmonary Exercise Testing Device
11. Pilot Testing Phase Ends; Expansion Of Sales Force Begins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... , ... January 20, 2017 , ... ... products to enhance people’s everyday lives, recently attended the January ECRM Trade Show ... ATP Science is known for its large range of supplements that keep the ...
(Date:1/20/2017)... ... January 20, 2017 , ... "TransFlare 4K Mystique comes ... of Final Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. ... Utilizing the Dragon Sensor,TransFlare 4K Mystique lens flare and light leak transitions have a ...
(Date:1/20/2017)... ... ... Angel”: a heartwarming and earnest tale of faith and believing in the path ... the creation of published author, Marjorie Lund-Fontaine, a former professional violinist, alumnus of The ... of her new book, Marjorie says, “‘The Angel’ was written as a fairytale, but ...
(Date:1/20/2017)... Farmville, NC (PRWEB) , ... January 20, 2017 ... ... the vPEP ® Oscillating Positive Expiratory Pressure (OPEP) device, was featured in ... article by Doug Pursley, MEd, RRT-ACCS, FAARC, “Analysis of Three Oscillating Positive ...
(Date:1/20/2017)... ... ... “Knowledge is God’s Lighthouse”: a moving and colorful collection of prayers that reminds ... published author, Gene Gaapf, a retired truck driver, and a long-time writer, whose published ... high school and have many different titles,” Gaapf mentions about his different works. “I ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... 2017 This report on the opioid induced ... of the global market. Large number of chronic pain ... constipation is a major side effect of consumption of ... targeted therapy has been prescribed to treat opioid induced ... medicines, and growing awareness about the therapy are the ...
(Date:1/19/2017)... , Jan. 19, 2017  Stealth BioTherapeutics Inc. ( ... treat mitochondrial dysfunction, today announced new additions to its ... as Chief Medical Officer, and Daniel Geffken ... that Jim Carr , Pharm.D. has been promoted ... are pleased to welcome Doug and Daniel to our ...
(Date:1/19/2017)... -- According to a study conducted by Persistence Market ... a CAGR of 6.5% during the forecast period 2016-2024. According to ... be the leading market for cryotherapy globally during the forecast period  ... Highlights from the ... and adequate supply of gas in order to provide smoother maintenance ...
Breaking Medicine Technology: