Navigation Links
HPV DNA testing over 50 percent more sensitive than cytology testing
Date:7/8/2010

HPV DNA testing for precancers and cervical cancers is over 50 per cent more sensitive than cytology testing for the same conditions a community-based study in Mexico has revealed. Results of the largest HPV DNA primary screening study ever to be performed in a Latin American country point to the readiness of HPV DNA testing for large-scale implementation in Mexico and are published online today (8 July 2010) in Cancer, Causes and Controls.

Attila Lorincz, Professor of Molecular Epidemiology at Barts and The London School of Medicine and Dentistry is among researchers behind the study which involved over 50,000 women, aged 20-70, undergoing routine cytology and high risk (HR) HPV DNA testing. All those who tested positive through cytology were referred to colposcopy, while the HPV DNA positive women were followed by repeat HPV DNA testing with colposcopy if they were repeat positive in one year. The study is a pilot implementation to determine the real world performance of routine HPV DNA testing and routine cytology testing in the Mexican IMSS health insurance system.

In women who were both cytology and HPV DNA positive the rate of precancer or cancer was 19.7 per cent whereas the corresponding rate in women who were positive by cytology alone was only 3 per cent. In women who were positive twice for HR HPV DNA (regarded as HPV persistent) the rate of precancer and/or cancers was 11.7 per cent.

Overall the sensitivity of HPV DNA testing for precancers and cervical cancers was 93.3 per cent versus only 40 per cent for cytology testing.

Professor Lorincz said of the results: "The data confirms that HR-HPV DNA testing is much more sensitive than cytology and that HPV testing also identifies women with high risk of serious cervical disease in an efficient and medically acceptable manner.

"The advantage of this new cervical cancer screening approach is that women who are HPV DNA positive can be quickly referred to colposcopy (within one year), thus catching the vast majority of the precancers and cancers. In contrast women who are HPV DNA negative can be safely made subject to much longer screening intervals (5 to 10 years) saving considerable costs for the Mexican health system. "


'/>"/>

Contact: Alex Fernandes
a.fernandes@qmul.ac.uk
44-207-882-7910
Queen Mary, University of London
Source:Eurekalert

Related medicine news :

1. New testing method hints at garlics cancer-fighting potential
2. Twenty-Five Years of HIV Blood Testing Helped to Positively Transform Global Health Crisis
3. Christine P. Carrington, President of NurseTesting Creative Solutions, Inducted into Cambridge Who's Who
4. New Allergy Testing Available for Patients Allergic to Penicillin: Determining the Presence of Penicillin Allergy is Essential to Patient Care
5. Breast Cancer Patients Often Confused by Genomic Testing
6. Study Results Validate Shape-HF as Simplified, Portable Cardiopulmonary Exercise Testing System
7. San Francisco AIDS Foundation Introduces HIV Testing to Sixth Street
8. Phybridge Inc. Joins the Cisco Developer Network and Completes Cisco Interoperability Verification Testing
9. UAB testing software program to improve safety among older drivers
10. Study Published by Circulation Heart Failure Reinforces Science Behind Shape-HF Cardiopulmonary Exercise Testing Device
11. Pilot Testing Phase Ends; Expansion Of Sales Force Begins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris F. ... AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking place ... the field of medical informatics, this prestigious award is presented to an individual whose ...
(Date:10/12/2017)... Maryland (PRWEB) , ... October 12, 2017 , ... ... magnetic drug delivery system that we intend to develop to enable prevention of ... can lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... FL (PRWEB) , ... October 12, 2017 , ... On ... holding a treadmill relay – Miles by Moonlight to raise money for the American ... $300 or more. , Teams will work together to keep their treadmills moving ...
(Date:10/12/2017)... ... 12, 2017 , ... Health Literacy Innovations (HLI), creator of ... and the Cancer Patient Education Network (CPEN), an independent professional organization that shares ... strategic alliance. , As CPEN’s strategic partner, HLI will help support CPEN ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... , Sept. 25, 2017  EpiVax, Inc., a ... design, and immune-engineering today announced the launch of ... development of personalized therapeutic cancer vaccines. EpiVax has ... exclusive access to enabling technologies to the new ... will lead EpiVax Oncology as Chief Executive Officer. ...
(Date:9/19/2017)... --  ZirMed Inc ., a recognized leader in cloud-based revenue ... been ranked #1 by its users for the seventh consecutive ... Survey. ZirMed was recognized as the top-ranked end-to-end revenue cycle ... over 200 beds and holds one of the longest #1 ... ...
(Date:9/12/2017)... Sept. 12, 2017  Consumer reviews on the independent review site ... the number one company for hearing aids, ranking it higher than ... brands. ... #1 by Consumers For Hearing Aids ... Hearing is an online store that provides high performance, state-of-the-art, German-engineered ...
Breaking Medicine Technology: