Navigation Links
HJF signs distribution agreement for antibody to evaluate prostate cancer
Date:2/18/2011

Rockville, Md. (Feb. 17, 2011)The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) has signed a licensing agreement with Biocare Medical, a biotechnology company based in Concord, Calif., for the exclusive worldwide sales and distribution rights for the immunohistochemistry of an antibody designed to detect tumor prevalence in prostate cancer patients.

The antibody was developed at the Center for Prostate Disease Research (CPDR), a multidisciplinary prostate cancer translational research program that is part of Department of Surgery at the Uniformed Services University of the Health Sciences in Bethesda, Md. HJF supports the center with research management and administrative services.

The mouse monoclonal anti-ERG antibody (CPDR ERG-MAb) can detect the presence of ERG proteins with a high degree of specificity in 50 percent to 70 percent of all patients with prostate cancer. The proteins are linked to cells capable of causing tumor growth. Using the antibody, researchers were able to identify the presence of ERG proteins with an unprecedented 99.9 percent accuracy. Detecting prostate tumor cells in pathologic specimens will aid in diagnostics, prognostics and patient monitoring.

Under a parallel cooperative research and development agreement, Biocare Medical will collaborate with researchers at CPDR, Armed Forces Institute of Pathology and Walter Reed Army Medical Center to further study the anti-ERG antibody and its clinical diagnostic potential.

The CPDR ERG-MAb provided the first insights into the ERG protein expression features in the prostate gland, indicating a strong correlation (97 percent) between the presence of ERG-positive prostatic intraepithelial neoplasia and ERG-positive carcinoma.

Groundbreaking research in the prostate cancer field has established ERG protein activation by recurrent gene fusions as one of the key genomic defects in prostate cancer. The protein is a promising diagnostic marker for identifying prostatic adenocarcinoma and distinguishing it from non-neoplastic prostate and other adenocarcinomas.

The antibody also may be used for detecting ERG protein alterations in other cancers, including endothelial cell derived tumors and acute myelogenous leukemia.


'/>"/>

Contact: JoAnn Sperber
jsperber@hjf.org
301-294-1234
Henry M. Jackson Foundation for the Advancement of Military Medicine
Source:Eurekalert

Related medicine news :

1. Early signs of heart disease in preadolescent children with type 1 diabetes
2. People Look to Eyes for Signs of Life, Study Finds
3. Obese children have signs of heart disease typically seen in middle-aged adults
4. U-M receives NIH, FDA grant to study adaptive clinical trial designs
5. Effective methods for detecting early signs of tremor
6. Friends, family detect early Alzheimers signs better than traditional tests
7. Infants May Display Subtle Autism Signs at 6 Months: Study
8. Mental Exercise May Only Hide Signs of Alzheimers
9. Telltale signs of bioterror
10. Signs of Autism May Show in Early Infancy
11. United Staes Company, First Defense Nasal Screens Signs Multi-Million Dollar Exclusive Distributorship Contract with U.A.E Company.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2017)... ... July 24, 2017 , ... SignatureCare Emergency Center ... be awarded for the fall semester to a deserving student. Get your applications ... 2017 scholarship was awarded to Mariana Castillo who is a nursing student at Prairie ...
(Date:7/24/2017)... , ... July 24, 2017 , ... ... (MCPS) have partnered together for a unique opportunity that helps high school girls succeed ... “Removing Barriers, Creating Opportunities.” Horizon Goodwill will host over 20 high school ...
(Date:7/24/2017)... , ... July 24, 2017 , ... The International Essential ... life-altering neurological condition called essential tremor (ET). The seminar will take place on Saturday, ... Woods Blvd., Independence, OH. The program will run from 9 a.m. to 12 p.m., ...
(Date:7/24/2017)... ... July 24, 2017 , ... The Topricin Companies, ... awareness for Topricin’s revolutionary, natural, after-burn skin care product, Topricin After Burn Cream. ... of long term skin conditions, including cancer. In the short term, overexposure ...
(Date:7/24/2017)... ... July 24, 2017 , ... Puregraft, the global ... the issuance of United States Patent Number 9,695,398 (the '398 patent) and South ... The '398 and '324 patents cover methods and systems for optimizing fat grafts ...
Breaking Medicine News(10 mins):
(Date:7/24/2017)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO ) announced ... operating results on Monday, August 7, 2017 after market ... p.m. ET. Shareholders ... of the conference call by dialing 877-201-0168 or 647-788-4901 ... 15 minutes prior to the call. A live webcast ...
(Date:7/21/2017)... RESEARCH TRIANGLE PARK, N.C. , July 21, 2017 ... ) announced today that it will report its second ... Thursday, July 27, 2017. ... July 27, 2017, at 9:00 a.m. Eastern Time.  The ... dialing 1-970-315-0533.  A rebroadcast of the teleconference will be ...
(Date:7/21/2017)... you know that PhRMA member companies invested $65.5 billion in research ... medicines, generics and the supply chain account for 14 percent of ... this (7 percent)? Or that the United States ... in high-growth biopharmaceutical startups? ... The biopharmaceutical industry accounts for ...
Breaking Medicine Technology: