Navigation Links
HJF signs distribution agreement for antibody to evaluate prostate cancer
Date:2/18/2011

Rockville, Md. (Feb. 17, 2011)The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) has signed a licensing agreement with Biocare Medical, a biotechnology company based in Concord, Calif., for the exclusive worldwide sales and distribution rights for the immunohistochemistry of an antibody designed to detect tumor prevalence in prostate cancer patients.

The antibody was developed at the Center for Prostate Disease Research (CPDR), a multidisciplinary prostate cancer translational research program that is part of Department of Surgery at the Uniformed Services University of the Health Sciences in Bethesda, Md. HJF supports the center with research management and administrative services.

The mouse monoclonal anti-ERG antibody (CPDR ERG-MAb) can detect the presence of ERG proteins with a high degree of specificity in 50 percent to 70 percent of all patients with prostate cancer. The proteins are linked to cells capable of causing tumor growth. Using the antibody, researchers were able to identify the presence of ERG proteins with an unprecedented 99.9 percent accuracy. Detecting prostate tumor cells in pathologic specimens will aid in diagnostics, prognostics and patient monitoring.

Under a parallel cooperative research and development agreement, Biocare Medical will collaborate with researchers at CPDR, Armed Forces Institute of Pathology and Walter Reed Army Medical Center to further study the anti-ERG antibody and its clinical diagnostic potential.

The CPDR ERG-MAb provided the first insights into the ERG protein expression features in the prostate gland, indicating a strong correlation (97 percent) between the presence of ERG-positive prostatic intraepithelial neoplasia and ERG-positive carcinoma.

Groundbreaking research in the prostate cancer field has established ERG protein activation by recurrent gene fusions as one of the key genomic defects in prostate cancer. The protein is a promising diagnostic marker for identifying prostatic adenocarcinoma and distinguishing it from non-neoplastic prostate and other adenocarcinomas.

The antibody also may be used for detecting ERG protein alterations in other cancers, including endothelial cell derived tumors and acute myelogenous leukemia.


'/>"/>

Contact: JoAnn Sperber
jsperber@hjf.org
301-294-1234
Henry M. Jackson Foundation for the Advancement of Military Medicine
Source:Eurekalert

Related medicine news :

1. Early signs of heart disease in preadolescent children with type 1 diabetes
2. People Look to Eyes for Signs of Life, Study Finds
3. Obese children have signs of heart disease typically seen in middle-aged adults
4. U-M receives NIH, FDA grant to study adaptive clinical trial designs
5. Effective methods for detecting early signs of tremor
6. Friends, family detect early Alzheimers signs better than traditional tests
7. Infants May Display Subtle Autism Signs at 6 Months: Study
8. Mental Exercise May Only Hide Signs of Alzheimers
9. Telltale signs of bioterror
10. Signs of Autism May Show in Early Infancy
11. United Staes Company, First Defense Nasal Screens Signs Multi-Million Dollar Exclusive Distributorship Contract with U.A.E Company.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2017)... ... September 19, 2017 , ... ... Mirixa Corporation recently unveiled the MirixaPro 6.0 platform. As the industry’s leading ... management services are delivered. Based on industry research and market feedback, the ...
(Date:9/19/2017)... (PRWEB) , ... September 19, 2017 , ... ... people searching for solutions to their neck and back pain with a reputable ... network. Allegion Spine Institute , formerly known as Nevada Spine Clinic was ...
(Date:9/19/2017)... ... September 19, 2017 , ... The ISO 9001 standard ... businesses and organizations become more efficient and improve customer satisfaction. ISO 9001:2015 was released ... own QMS, with a deadline of September 2018. , As described in ...
(Date:9/19/2017)... , ... September 19, 2017 ... ... DACVIM, a board-certified veterinary oncologist, has agreed to serve as strategic adviser ... Dr. Tripp is founder of the Bridge Animal Referral Center (BARC) ...
(Date:9/19/2017)... ... , ... Ron Norman, CEO of Team Decades, http://www.teamdecades.com , stressed to ... than generic impression in the job market if one is looking for career expansion. ... that the first impression they give off is not a good one," says Norman, ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... ALLENTOWN , Pa. and KALAMAZOO, Mich. ... Allentown, Penn. , and OptiMed Specialty Pharmacy ... a business partnership to offer a strategic hub service ... PMD Healthcare,s highly sought-after personal spirometer, Spiro PD 2.0, ... A spirometer is a medical device used ...
(Date:9/12/2017)... 12, 2017   EcoVadis , the leading platform for environmental, social ... annual edition of its Global CSR Risk and Performance Index. The report ... based on Scorecard Ratings that analyzed nearly 800,000 data points across the ... ... ...
(Date:9/9/2017)... ... ... Monday, September 18 th .The Brain Tumor Foundation (BTF) begins a week-long ... BTF,s Mobile MRI Unit – a 70 Ft. ... brings its nationwide initiative, the Road to Early Detection Sponsor-A-City Campaign to ...
Breaking Medicine Technology: