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HIV's path out of Africa: Haiti, the US then the world
Date:10/29/2007

ity of subtype B than does the U.S.

"The U.S., Australia, Europe plus many countries have just a subset of the subtype B diversity you see in Haiti," Worobey said.

The virus moved from Africa to Haiti in about 1966, he said. Haiti has more diversity of HIV than does the U.S. and other countries because the virus has been there longer and had more time to mutate.

The finding helps explain the early observations of a high prevalence of AIDS in Haiti, Worobey said. "The virus had simply been there longer."

"The main challenge of developing a vaccine against HIV is its tremendous genetic diversity," he said.

Knowing the gamut of diversity within subtype B could be important for effectively developing and testing vaccines that will work in Haiti, Worobey said.

Worobey's next step is following the trail of HIV even further back in time using older archival samples.


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Contact: Mari N. Jensen
mnjensen@email.arizona.edu
520-626-9635
University of Arizona
Source:Eurekalert

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