Navigation Links
HIV vaccine regimen demonstrates modest preventive effect in Thailand clinical study
Date:9/24/2009

In an encouraging development, an investigational vaccine regimen has been shown to be well-tolerated and to have a modest effect in preventing HIV infection in a clinical trial involving more than 16,000 adult participants in Thailand. Following a final analysis of the trial data, the Surgeon General of the U.S. Army, the trial sponsor, announced today that the prime-boost investigational vaccine regimen was safe and 31 percent effective in preventing HIV infection.

"These new findings represent an important step forward in HIV vaccine research," says Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH, which provided major funding and other support for the study. "For the first time, an investigational HIV vaccine has demonstrated some ability to prevent HIV infection among vaccinated individuals. Additional research is needed to better understand how this vaccine regimen reduced the risk of HIV infection, but certainly this is an encouraging advance for the HIV vaccine field.

"We thank the trial staff in Thailand and the United States for their years of effort in successfully conducting this study and the study participants and the people of Thailand for their long-standing support of HIV vaccine research," Dr. Fauci adds.

The Thai Phase III HIV vaccine study, also known as RV144, opened in October 2003. The placebo-controlled trial tested the safety and effectiveness of a prime-boost regimen of two vaccines: ALVAC-HIV vaccine (the primer dose), a modified canarypox vaccine developed by Sanofi Pasteur, based in Lyon, France, and AIDSVAX B/E vaccine (the booster dose), a glycoprotein 120 vaccine developed by Vaxgen Inc., and now licensed to Global Solutions for Infectious Diseases (GSID), based in South San Francisco, Calif. The vaccines are based on the subtype B and E HIV strains that commonly circulate in Thailand. The subtype B HIV strain is the one most commonl
'/>"/>

Contact: Kathy Stover
stoverk@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. DNA vaccine against multiple sclerosis appears safe, potentially beneficial
2. HPV vaccine does not appear to be effective for treating pre-existing HPV infection
3. Vaccine Stops Alzheimers Brain Tangles
4. Human Papilloma Virus vaccines may decrease chances of oral cancer
5. U.S. Teens Fall Short on Vaccine Coverage
6. Nasal Anthrax Vaccine Proves Effective in Animal Study
7. Hot ice, measuring depression, perfect invisibility and flu vaccine incentives
8. Bioniche Receives $2 Million Government Grant For Market Development Related to its E. coli O157:H7 Cattle Vaccine
9. Iomai Patch-Based Vaccine Cut Rate of Travelers Diarrhea by 75 Percent in Phase 2 Field Study
10. FDA approves expanded label for FluMist (influenza virus vaccine live, intranasal) to include childr
11. MedImmune Licenses Reverse Genetics Technology to GlaxoSmithKline for Use in Influenza Vaccine Development and Production
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2009)... employment and sociodemographic characteristics involved in the exposure of ... they often work standing up or have to lift ... 62% say they are frequently exposed to some physical ... breastfeeding women are especially sensitive to exposure to workplace ... and a researcher at the Higher Centre for Public ...
(Date:12/17/2009)... infection employed by Salmonella has to be ... group "Cytoskeleton Dynamics". The group,s results have now been ... " Cellular Microbiology ". , Salmonella are ... and absence of oxygen and thus propagate in the ... egg dishes such as mayonnaise or raw milk products ...
(Date:12/17/2009)... Personal Stories of Inspiration on How Exercise Has Helped, Healed, and ... ... 2009 -- The International Health, Racquet & Sportsclub Association (IHRSA) announced ... it is urging Americans of all ages and abilities to make ... a culture of movement in America wherein regular daily exercise is ...
(Date:12/17/2009)... discover gender differences that explain the aging inequity ... Dermatologists have discovered yet another gender inequity: Women ... as they age than men do. , The ... study provides "irrefutable scientific evidence," said Dr. Foad ... editor-in-chief of the Aesthetic Surgery Journal . ...
(Date:12/17/2009)... Inc. (Nasdaq: NBIX ) today reported that it ... an aggregate of 4,784,689 primary shares of its common ... $2.09 per share, raising aggregate gross proceeds to Neurocrine ... close on or about December 22, 2009, subject to ... statement relating to the shares of common stock to ...
Breaking Medicine News(10 mins):Health News:Almost two-thirds of pregnant women believe they are regularly exposed to physical risk at work 2Health News:Invasion without a stir 2Health News:IHRSA's Campaign for a Healthier America Calls on All Americans to Curtail Health Care Costs in 2010 by Becoming Physically Active 2Health News:IHRSA's Campaign for a Healthier America Calls on All Americans to Curtail Health Care Costs in 2010 by Becoming Physically Active 3Health News:IHRSA's Campaign for a Healthier America Calls on All Americans to Curtail Health Care Costs in 2010 by Becoming Physically Active 4Health News:IHRSA's Campaign for a Healthier America Calls on All Americans to Curtail Health Care Costs in 2010 by Becoming Physically Active 5Health News:Mouth Area Wrinkles More in Women Than Men 2Health News:Mouth Area Wrinkles More in Women Than Men 3Health News:Neurocrine Announces Sale of 4,784,689 Shares of Common Stock, to Raise Proceeds of $10 Million 2Health News:Neurocrine Announces Sale of 4,784,689 Shares of Common Stock, to Raise Proceeds of $10 Million 3
... disease that is preventable and curable, yet every 30 seconds ... posed one of the biggest challenges //to healthcare experts and ... a punch through an innocuous looking mite. It is apt ... proud much before the unique selling 'Made in China' tag, ...
... called as 'Black Disease' as commented by Phill Wilson, executive ... is because of the growing AIDS population among the blacks, ... across the country. African-Americans comprise 13% of the total population ... prone to disease 10 times more than the whites. ...
... men with low testosterone levels appears to have little ... that this therapy may be harmful, according to a ... theme issue on men's health. ,Leonard S. ... University of California, Los Angeles, presented the findings of ...
... tract symptoms who received a combination therapy were more likely ... one medication, according to a study in the November 15 ... ,Steven A. Kaplan, M.D., of Weill Cornell Medical ... at a JAMA media briefing on men's health in New ...
... been sequencing the genome of an organism called Mycobacterium-w ... complete// genome that holds promise in the treatment of ... evidence that a vaccine made from killed Mw drastically ... resistant (MDR) variety is driving this project more than ...
... who suffer from migraine are more at risk of heart ... painful neurological condition, of which the most common symptom is ... with migraines were more likely to have high blood pressure ... migraines, a study done on 20,084 men revealed. ...
Other Medicine News:Health News:Malaria: The Invincible Might of a Parasite, Nestled in a 'Mite' 2Health News:Malaria: The Invincible Might of a Parasite, Nestled in a 'Mite' 3Health News:Testosterone Replacement Therapy Appears Safe for Prostate 2Health News:Combination Therapy More Effective for Treating Lower Urinary Tract Symptoms 2Health News:India Finds New Use for an Old Bug 2Health News:India Finds New Use for an Old Bug 3
(Date:12/16/2009)... YORK, December 16 International, ... publication of GFT505 (80 mg/day),data presented ... internationally,recognized expert scientists and clinicians critically ... continuing role of generic lipid-modifying,treatments, fenofibrate ... is commonly observed in patients with ...
(Date:12/16/2009)... 16 Boston Scientific Corporation (NYSE: ... Directors has elected Nelda Connors as a Director. ... Electrical and Metal Products division of Tyco International. ... holding several positions in operations and general management. ... number of executive and management capacities with Ford, Chrysler ...
(Date:12/16/2009)... Wash., Dec. 16 Verathon®, maker ... to announce that portable bladder volume ultrasound ... CDC guidelines for the Prevention of Catheter-Associated ... CDC guidelines, introduced in early November 2009, ... to 1981. The guidelines are located ...
Breaking Medicine Technology:International, Well-Known Scientific Experts Say That New GFT505 Data Unlikely to Have the Potential to Affect the Established Role of Generic Fenofibrate and Bezafibrate in Managing Atherogenic Dyslipidemia 2International, Well-Known Scientific Experts Say That New GFT505 Data Unlikely to Have the Potential to Affect the Established Role of Generic Fenofibrate and Bezafibrate in Managing Atherogenic Dyslipidemia 3Boston Scientific Announces Election of Nelda Connors to Its Board of Directors 2Boston Scientific Announces Election of Nelda Connors to Its Board of Directors 3New 2009 CDC Guidelines for the Prevention of Catheter-Associated Urinary Tract Infections Include Bladder Volume Ultrasound 2New 2009 CDC Guidelines for the Prevention of Catheter-Associated Urinary Tract Infections Include Bladder Volume Ultrasound 3New 2009 CDC Guidelines for the Prevention of Catheter-Associated Urinary Tract Infections Include Bladder Volume Ultrasound 4New 2009 CDC Guidelines for the Prevention of Catheter-Associated Urinary Tract Infections Include Bladder Volume Ultrasound 5Caliper Life Sciences Second Quarter 2009 Financial Results Conference Call Notice 13071 1Caliper Life Sciences Second Quarter 2009 Financial Results Conference Call Notice 13071 2How To Reduce Cost Without Sacrificing Your Health Coverage 51954 1How To Reduce Cost Without Sacrificing Your Health Coverage 51954 2Many Veterans Need Mental Health Care 51950 1Many Veterans Need Mental Health Care 51950 2Many Veterans Need Mental Health Care 51950 3Many Veterans Need Mental Health Care 51950 4
For the determination of urea nitrogen in human serum....
Intended for the quantitative determination of urea nitrogen in serum. Reaction: kinetic. Wavelength: 340 nm. Linearity: 150 mg/dL (53.4 mmol/L urea) at 37C....
Intended for the quantitative determination of total bilirubin in serum. Modified evelynmalloy method. Endpoint reaction. Wavelength: 555 nm. Linearity: 20 mg/dl (340 mol/l)...
... spectrophotometer designed specifically to run 24 hours ... rugged hardware, proven optical performance and a ... traditional spectrophotometry to obtain results quickly, accurately ... up to eight, 1 cm Biocell cuvettes ...
Medicine Products: