HIV therapy in pregnancy-data support WHO recom...( HIV therapy in pregnancy-data suppo...),Health

In an observational cohort study from Cte d'Ivoire, Fran ois Dabis and colleagues report on prevention of mother-to-child HIV transmission among women receiving antiretroviral therapy according to World Health Organization recommendations.

Citation: Tonwe-Gold B, Ekouevi DK, Viho I, Amani-Bosse C, Toure S, et al. (2007) Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: Evaluation of a two-tiered approach. PLoS Med 4(8): e257.

IN YOUR ARTICLE, PLEASE LINK TO THIS URL, WHICH WILL PROVIDE ACCESS TO THE PUBLISHED PAPER: http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0040257

PRESS-ONLY PREVIEW OF THE ARTICLE: http://www.plos.org/press/plme-04-08-dabis.pdf

CONTACT:
Franois Dabis
INSERM Unit 593
Insitut de Sant Publique Epid miologie et Dveloppement (ISPED)
Universit Victor Segalen Bordeaux 2
146 rue Lo Saignat
Bordeaux, 33076
France
+33 557571436
+33 557574528 (fax)
francois.dabis@isped.u-bordeaux2.fr

The accepted definition of severe malaria is appropriate for clinical purposes, but Philip Bejon and colleagues show its specificity in clinical trials may be improved by a parasite density threshold and by excluding children with certain conditions. The article is discussed in a related perspective.

Citation: Bejon P, Berkley JA, Mwangi T, Ogada E, Mwangi I, et al. (2007) Defining childhood severefalciparum malaria for interventionstudies. PLoS Med 4(8): e251.

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