Navigation Links
HIV prevention researchers to compare common ARV as a pill and vaginal gel in unique study
Date:7/9/2008

PITTSBURGH, July 9 , 2008 In battle with an epidemic that has outpaced nearly all efforts to contain it, researchers are turning to strategies centered on the same antiretroviral (ARV) drugs that have been used successfully to treat HIV in hopes they will be as effective a stronghold for preventing the virus. For women, who make up nearly half of the 33 million people living with HIV/AIDS worldwide, the ARV tenofovir has particular promise because it can be formulated as either an oral tablet or a vaginal gel to be used daily. But ARV-based prevention approaches are not without scientific and practical challenges. The Microbicide Trials Network (MTN) is taking aim at among the most pressing of these challenges in the first clinical trial to directly compare the tablet and vaginal gel formulations of tenofovir.

In part because certain cells in the vagina are easy targets for the virus, women are more than twice as likely as their male partners to acquire HIV through sexual intercourse. As such, the clinical study, known as MTN-001, seeks to understand how each formulation of tenofovir works in these infection-prone cells, information that will help researchers determine the optimal doses needed to achieve drug concentrations most likely to prevent HIV in women.

MTN-001 also looks to understand the factors that influence women's preferences for one daily approach over another, because not even the best approach will be effective if women don't use it.

MTN-001 is a Phase II study designed to evaluate women's adherence to and acceptance of three daily regimens of tenofovir tenofovir gel, tenofovir disoproxil fumarate tablets and the two together and the pharmacokinetics, or how the drug is absorbed by and distributed in the body over time, of each regimen. The study will enroll 144 sexually active HIV-negative women who will follow all three regimens, each for six weeks with one week between when no study product is used. In the Unite
'/>"/>

Contact: Lisa Rossi
rossil@upmc.edu
412-916-3315
Microbicide Trials Network
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Breast cancer prevention practices vary across Canada
2. School-based overweight prevention program may cut risk of eating disorders among girls
3. MultiVu Video Feed: PUBLIC HEALTH EXPERTS CONVENE TO DISCUSS THE TREATMENT AND PREVENTION OF RABIES
4. Jump in Youth Suicide Prompts National Childrens Charity KidsPeace to Issue Tips on Prevention, Warning Signs
5. ABQAURP Announces Certificate Course in Medical Error Prevention
6. Scientists, physicians present latest findings in personalized cancer treatment and prevention
7. Experts Offer Tips on Lung Cancer Prevention
8. Meth Project Advertisements Selected for National Prevention Campaign
9. SAVE Recognizes National Suicide Prevention Week
10. Updated GOLD report presents new understandings in diagnosis, treatment and prevention of COPD
11. GP targets on heart disease should be simpler and based more on treatment and prevention
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2014)... November 27, 2014 Two international trainers ... procedure will help one person with significant needs ... Saj Jivraj and Dr. Mamaly Reshad of the Anacapa ... have launched a website devoted to helping dentist learn ... the website would be devoted to helping a patient ...
(Date:11/27/2014)... November 27, 2014 “Wekho” was featured on ... latest and coolest mobile applications on the iOS, Android, and ... of NewsWatch, conducted the app review and shared ... of people. , An interesting new way to travel and ... Android devices. It’s called Wekho and it’s a free ...
(Date:11/27/2014)... Aliso Viejo, California (PRWEB) November 27, 2014 ... have announced a new plugin entitled ProPip, taking FCPX to ... picture in picture effect with a few clicks of a ... is a time saver that our users will appreciate.” , ... with full customization leaving the possibilities truly endless. ProPip is ...
(Date:11/27/2014)... November 27, 2014 This is ... Global Insulin industry. For an overview analysis, the ... application, industry chain structure, industry overview, policy analysis, ... Insulin industry covers information on policy, plans ... cost structure and much more. , ...
(Date:11/27/2014)... 27, 2014 Aria Health President ... employees, prepared and donated 200 Thanksgiving dinners on ... House , a non-profit, community-based organization committed to ... Philadelphia. The dinners were assembled in the dining ... and distributed to vulnerable low income seniors in ...
Breaking Medicine News(10 mins):Health News:World-Renowned Oxnard All-on-4™ Dental Implants Experts to Give Away Full Mouth Rehabilitation Annually 2Health News:World-Renowned Oxnard All-on-4™ Dental Implants Experts to Give Away Full Mouth Rehabilitation Annually 3Health News:World-Renowned Oxnard All-on-4™ Dental Implants Experts to Give Away Full Mouth Rehabilitation Annually 4Health News:World-Renowned Oxnard All-on-4™ Dental Implants Experts to Give Away Full Mouth Rehabilitation Annually 5Health News:A New Geolocation Mobile Application and was Featured on NewsWatch Television on October 30, 2014 2Health News:Pixel Film Studios released ProPip plugin Exclusively for Final Cut Pro X 2Health News:Pixel Film Studios released ProPip plugin Exclusively for Final Cut Pro X 3Health News:Insulin Industry Analysis (Supply, Consumption) for China, America, Korea, France & Japan Research Now at ReportsnReports 2Health News:Insulin Industry Analysis (Supply, Consumption) for China, America, Korea, France & Japan Research Now at ReportsnReports 3Health News:Aria Health Prepares and Donates 200 Thanksgiving Dinners 2
... the Doubletree Hotel in Oak Brook ... 23 The Perinatal Nursing Advisory Council and the March of ... lactation consultants, and the community to the March of Dimes ... Oak Brook, Illinois. All healthcare professionals caring for moms ...
... retinoid tretinoin not the culprit , , FRIDAY, Jan. 23 (HealthDay ... that was tried as a possible skin cancer preventative in ... of several veterans participating in that research. , The ... risk of death was seen in those using retinoid tretinoin ...
... contradicts belief that death rate associated with condition has ... death rate for patients with acute respiratory distress syndrome ... that contradicts the common belief there,s been a steady ... , The researchers reviewed studies conducted between 1984 and ...
... inflammatory bowel disease have higher concentrations of folate in their blood than ... the University of California, San Francisco and UC Berkeley. The findings bring ... to folate - also known as folic acid - deficiency. , ... ...
... Ohio, Jan. 23 Patricia A. Furlong, Founding ... (PPMD), the largest non-profit organization in the United ... muscular dystrophy (Duchenne), announced the one year anniversary ... resources and needs of the Duchenne and Becker ...
... 23 Heartland Information Services,( www.heartlandis.com ), headquartered ... outsourced transcription companies in a report released in ... firm,( www.KLASresearch.com ). In their report, Top 20 ... 2008, Heartland moved up for the third year ...
Cached Medicine News:Health News:March of Dimes 34th Annual Perinatal Conference For Nurses, Health Educators, Social Workers and Other Healthcare Pros Caring for Moms and Babies 2Health News:Acne Cream Not Linked to Raised Death Risk 2Health News:Acne Cream Not Linked to Raised Death Risk 3Health News:Acute Respiratory Distress Syndrome as Deadly as Ever 2Health News:Children with Inflammatory Bowel Disease Have Surprisingly High Folate Levels, Study Finds 2Health News:Children with Inflammatory Bowel Disease Have Surprisingly High Folate Levels, Study Finds 3Health News:Children with Inflammatory Bowel Disease Have Surprisingly High Folate Levels, Study Finds 4Health News:DuchenneConnect Celebrates One Year Anniversary 2Health News:DuchenneConnect Celebrates One Year Anniversary 3Health News:DuchenneConnect Celebrates One Year Anniversary 4Health News:Heartland Information Services Moves Up to 2nd Place in National Survey for Outsourced Transcription 2
(Date:11/26/2014)... , Nov. 26, 2014 Zynerba Pharmaceuticals ... development of innovative transdermal synthetic cannabinoid treatments, today announced ... 26th Annual Healthcare Conference 2014. The conference will be ... Palace in New York . Zynerba,s ... at 4:50 pm on Tuesday, December 2. ...
(Date:11/26/2014)... Nov. 26, 2014 The medical magnetic ... rate of 4%, with world market revenues for ... MRI and other types of medical imaging have ... of numerous medical conditions in children and adults, ... Kalorama,s report, Medical Imaging Markets , analyzes ...
(Date:11/26/2014)... CHARLOTTE, N.C. , Nov. 25, 2014  At ... San Antonio this October, KaVo Kerr Group ... Institute Technology Expo, offering attendees the opportunity to see ... to well-respected key opinion leaders deliver lectures on the ... Kerr Group products include the new DEXIS CariVu Caries ...
Breaking Medicine Technology:Zynerba Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 2014 2Kalorama: Steady Growth in the Medical MRI Market 2Kalorama: Steady Growth in the Medical MRI Market 3KaVo Kerr Group Showcased in Pride Institute Technology Expo at ADA Annual Meeting 2KaVo Kerr Group Showcased in Pride Institute Technology Expo at ADA Annual Meeting 3
... Medaxial, the healthcare value communication specialist, today ... Enterprise in recognition of its international trade achievements. ... most prestigious business accolade, bestowed by Her Majesty Queen ... have achieved outstanding results in international trade, innovation or ...
... 20, 2012  In a time of rapid evolution ... their use of technology, applications and workflow. Netsmart ... health and human services organizations nationwide, today announced ... providers deliver accountable, recovery-based care in the increasingly ...
Cached Medicine Technology:Pharmaceutical Industry Service Company Awarded The UK's Most Prestigious Business Accolade in Recognition of Outstanding Achievement in International Trade 2Pharmaceutical Industry Service Company Awarded The UK's Most Prestigious Business Accolade in Recognition of Outstanding Achievement in International Trade 3Netsmart's Focus on Innovation to Help Health and Human Service Providers Span the Spectrum of Care in the Healthcare 3.0 Environment 2Netsmart's Focus on Innovation to Help Health and Human Service Providers Span the Spectrum of Care in the Healthcare 3.0 Environment 3Netsmart's Focus on Innovation to Help Health and Human Service Providers Span the Spectrum of Care in the Healthcare 3.0 Environment 4
... basic Thermomixer is a compact model that ... x 1.5 ml tubes. Impressive features of ... design, and high stabilityeven at maximum mixing ... gentle to vigorous mixing, including intermittent mixing; ...
... 10k units Pen.,10k ug ... BioWhittaker Cell Culture Reagent and ... accordance with cGMP regulations and ... assure compatibility. , Typical Properties, ...
... 25,000 units Penicillin/25,000 ug ... Culture Reagent and Buffer ... accordance with cGMP regulations ... tested to assure compatibility. ...
Penicillin-Streptomycin-Glutamine (100X) liquid...
Medicine Products: