Navigation Links
HIV prevention researchers to compare common ARV as a pill and vaginal gel in unique study
Date:7/9/2008

PITTSBURGH, July 9 , 2008 In battle with an epidemic that has outpaced nearly all efforts to contain it, researchers are turning to strategies centered on the same antiretroviral (ARV) drugs that have been used successfully to treat HIV in hopes they will be as effective a stronghold for preventing the virus. For women, who make up nearly half of the 33 million people living with HIV/AIDS worldwide, the ARV tenofovir has particular promise because it can be formulated as either an oral tablet or a vaginal gel to be used daily. But ARV-based prevention approaches are not without scientific and practical challenges. The Microbicide Trials Network (MTN) is taking aim at among the most pressing of these challenges in the first clinical trial to directly compare the tablet and vaginal gel formulations of tenofovir.

In part because certain cells in the vagina are easy targets for the virus, women are more than twice as likely as their male partners to acquire HIV through sexual intercourse. As such, the clinical study, known as MTN-001, seeks to understand how each formulation of tenofovir works in these infection-prone cells, information that will help researchers determine the optimal doses needed to achieve drug concentrations most likely to prevent HIV in women.

MTN-001 also looks to understand the factors that influence women's preferences for one daily approach over another, because not even the best approach will be effective if women don't use it.

MTN-001 is a Phase II study designed to evaluate women's adherence to and acceptance of three daily regimens of tenofovir tenofovir gel, tenofovir disoproxil fumarate tablets and the two together and the pharmacokinetics, or how the drug is absorbed by and distributed in the body over time, of each regimen. The study will enroll 144 sexually active HIV-negative women who will follow all three regimens, each for six weeks with one week between when no study product is used. In the Unite
'/>"/>

Contact: Lisa Rossi
rossil@upmc.edu
412-916-3315
Microbicide Trials Network
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Breast cancer prevention practices vary across Canada
2. School-based overweight prevention program may cut risk of eating disorders among girls
3. MultiVu Video Feed: PUBLIC HEALTH EXPERTS CONVENE TO DISCUSS THE TREATMENT AND PREVENTION OF RABIES
4. Jump in Youth Suicide Prompts National Childrens Charity KidsPeace to Issue Tips on Prevention, Warning Signs
5. ABQAURP Announces Certificate Course in Medical Error Prevention
6. Scientists, physicians present latest findings in personalized cancer treatment and prevention
7. Experts Offer Tips on Lung Cancer Prevention
8. Meth Project Advertisements Selected for National Prevention Campaign
9. SAVE Recognizes National Suicide Prevention Week
10. Updated GOLD report presents new understandings in diagnosis, treatment and prevention of COPD
11. GP targets on heart disease should be simpler and based more on treatment and prevention
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/3/2015)... Lenexa, KS (PRWEB) , ... July 03, 2015 ... ... firm dedicated exclusively to healthcare providers, has been retained to lead a national ... Okla. One of the top-ranked executive search firms in the healthcare industry, B. ...
(Date:7/3/2015)... (PRWEB) , ... July 03, 2015 , ... Jennifer Renee ... First Choice Emergency Room , the largest network of independent freestanding emergency rooms in ... facility medical director of our Sienna Plantation facility,” said Executive Medical Director of First ...
(Date:7/3/2015)... ... July 03, 2015 , ... Every year, One-to-1 Fitness and the ... members of the Red Deer community with free fitness training and indoor fitness boot ... food, events and entertainment raised thousands of charity dollars and ended with a $10,000 ...
(Date:7/2/2015)... ... July 02, 2015 , ... sweetFrog Enterprises, LLC. is pleased to announce ... 19th sweetFrog store located in the Lone Star State. The premium frozen yogurt chain ... 2014. , The store, which opened July 1 at Duke’s Travel Plaza, is located ...
(Date:7/2/2015)... ... July 02, 2015 , ... Many Fourth of July celebrations ... why Amica Insurance is sharing some tips to promote the proper use ... people go to the emergency room daily with fireworks-related injuries in the month surrounding ...
Breaking Medicine News(10 mins):Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 2Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 3Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 2Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 3Health News:Red Deer Fitness Studio Raises $10,000 for Charity Organization with 24-Hour Train-a-Thon 2Health News:Red Deer Fitness Studio Raises $10,000 for Charity Organization with 24-Hour Train-a-Thon 3Health News:sweetFrog Expands Texas Footprint with Location in Canton 2Health News:6 Fireworks Safety Tips from Amica Insurance 2
... are obsessed,with red-carpet fashion, but Hollywood based "Dentist to ... a critic,s eye for,the best and worst smiles., ... smiles are really easy to notice during red carpet ... The Oaks Center for Cosmetic,Dentistry., The most outstanding ...
... to Streamline Hospital,s Operations and Revenue ... ... a $1,billion-plus global services firm that specializes in enabling,transformation of its clients, ... with Mount Sinai Hospital of Queens,part of New York-based Mount Sinai Medical ...
... Hero may help reduce global warming by making people ... in the 2007 European Satellite Navigation Competition, sponsored by ... technology to track journeys. , Concerned about global warming, ... their generation of carbon dioxide (CO2). One option is ...
... Corp. and,customer PHI, Inc. celebrated the execution of ... and the milestone achievement of 20,000 fleet,hours with ... at,Heli-Expo. Sikorsky Aircraft is a subsidiary of United ... http://www.newscom.com/cgi-bin/prnh/20060403/SIKORSKYLOGO ), Under the options contract, ...
... Ore. Oregon Health & Science University Cancer Institute ... men with advanced prostate cancer can take a much-needed ... randomized study, led by principal investigator Tomasz Beer, M.D., ... the Grover C. Bagby Endowed Chair for Cancer Research, ...
... 25 In response to the,Centers for Medicare ... this week, Kidney Care Partners (KCP) -- an ... manufacturers,working together to improve quality of care for ... CMS for issuing its long-awaited,report which recognizes the ...
Cached Medicine News:Health News:Keane Wins Revenue Cycle Management Implementation With Mount Sinai Hospital of Queens 2Health News:Keane Wins Revenue Cycle Management Implementation With Mount Sinai Hospital of Queens 3Health News:Tracking your carbon footprint 2Health News:Tracking your carbon footprint 3Health News:Sikorsky Aircraft and PHI Celebrate Fleet Expansion and 20K Milestone at Heli-Expo 2Health News:OHSU Cancer Institute research gives hope for chemo holidays for men with advanced prostate cancer 2Health News:Statement by Dr. Edward Jones, Chairman of Kidney Care Partners in Response to CMS Payment Bundling Report 2Health News:Statement by Dr. Edward Jones, Chairman of Kidney Care Partners in Response to CMS Payment Bundling Report 3
(Date:7/2/2015)... 25, 2015 Research and Markets( http://www.researchandmarkets.com/research/nlfg34/cancer ... by Technology, Imaging and by Application - Forecast to 2020" ... is expected to reach $13.1 Billion in 2020 from an estimated ... The market is dominated by North America ... , and Rest of the World (RoW). The cancer diagnostics ...
(Date:7/2/2015)... Mass. , July 2, 2015   ... and European retinal specialists identify less frequent dosing ... edema (DME), due to the burden on both ... anti-vascular endothelial growth factor (VEGF) injections, which are ... Allergan/Molecular Partners, abicipar pegol, which is in development ...
(Date:7/2/2015)... 2015 BGI gab heute bekannt, ... vom American College of Pathologists (CAP) akkreditiert ... erste klinische Next-Generation-Sequencing Labor, das in ... und somit die höchsten Standards an klinischer ... FDA - 21 CFR Part 11 konformen ...
Breaking Medicine Technology:Global Cancer Diagnostics Market Report 2015 - Technology, Imaging and by Applications Forecasts to 2020 for the $13 Billion Industry 2Retinal Specialists Indicate Strong Desire for DME Therapies Which Induce Greater Vision Gains or are Administered Less Frequently Than Currently Approved Anti-VEGF Therapies 2Retinal Specialists Indicate Strong Desire for DME Therapies Which Induce Greater Vision Gains or are Administered Less Frequently Than Currently Approved Anti-VEGF Therapies 3BGI erhält Akkreditierung vom College of American Pathologists (CAP) 2
... MOUNTAIN VIEW, Calif., April 28, 2011 IRIDEX Corporation (NASDAQ: ... quarter 2011 financial results after the market closes on ... the Company will host a conference call with the investment community ... Thursday, May 5, 2011 to discuss the results ...
... April 28, 2011 PharmaNet Development Group, Inc., a ... generic drug and medical device companies, announced today that ... President, Corporate Quality Assurance. "We are ... Newman, MD, President, PharmaNet Development Group. "Valerie brings deep ...
Cached Medicine Technology:
Metrika's A1cNow Monitor is the first ever single-use test for hemoglobin A1c, it is the "gold standard" indicator of diabetes management. The test is easy to use, needs only a drop of blood and take...
Micromat II Hemoglobin A1c instrument is an easy-to-use, accurate and precise instrument with an requirement of only 10 L of capillary or venous sample....
... CELL-DYN WorkCell delivers complete hematology automation to ... A modular configuration provides the flexibility to ... includes one Navigator module, one Load module, ... code reader. The basic system will incorporate ...
... a manual hemostasis analyzer that is ... - PTs, aPTTs, thrombins, fibrinogens and ... low-volume testing, this analyzer is small ... offering time and labor saving benefits. ...
Medicine Products: