Navigation Links
HIV plus HPV leads to increased anal cancer risk in men
Date:12/3/2013

Human papillomavirus, or HPV, which can cause cervical cancer in women, is also known to cause anal cancer in both women and men. Now, a study led by researchers at the UCLA School of Nursing has found that older HIV-positive men who have sex with men are at higher risk of becoming infected with the HPVs that most often cause anal cancer.

The researchers also report that smoking increases the risk of infection with specific types of HPV among both HIV-infected and uninfected older men by up to 20 percent. This is the first large U.S. study of a group of HIV-infected and uninfected men between the ages of 40 and 69 who have sex with men. Study participants were examined twice a year for up to 25 years.

"Invasive anal cancer is a health crisis for gay, bisexual and other men who have sex with men," said Dorothy J. Wiley, associate professor at the UCLA School of Nursing and lead author of the study, which was published Nov. 20 in the journal PLOS ONE. "Right now, invasive anal cancer rates among HIV-infected men who have sex with men surpass rates for seven of the top 10 cancers in men."

The study, which involved more than 1,200 participants, was performed at four sites in the United States. Nearly 49 percent of the men were HIV-positive. During semi-annual visits, all the men were examined for demographic, sexual, behavioral and HIV-infection characteristics and were tested for HPV.

The researchers found that HPV infections were common among all the men in the study and that the proportion of men affected by HPV remained consistently high across the 40󈞱 age range. However, HIV-infected men between the ages of 40 and 69 showed a higher risk for HPV infection than HIV-uninfected men.

The study also found that for HIV-positive men, taking antiretroviral therapies as prescribed appeared to lower their risk for the HPV infections that cause cancers. Avoiding tobacco use also lowered the risk of HPV infections among all the men.

"This study highlights the benefit of adhering to HIV treatment, which among HIV-infected men who have sex with men, is important for cancer-prevention strategies," Wiley said.

The next step in this research is to begin looking at ways to develop better, more effective HPV infectionprevention strategies, including vaccination for age-eligible males and screening and treatment programs for high-risk men who have sex with men to prevent invasive cancers.

"Right now, we perform colonoscopies to prevent colon cancer, where 53 men per 100,000 are diagnosed annually," Wiley said. "Unfortunately, we do not provide screening tests routinely for anal cancer for men who have sex with en, where the numbers are much higher 78 men per 100,000."


'/>"/>

Contact: Laura Perry
lperry@sonnet.ucla.edu
310-794-4022
University of California - Los Angeles
Source:Eurekalert

Related medicine news :

1. Epilepsy Leads to More Brain Abnormalities Over Time
2. How a cancer drug leads to diabetes
3. Georgetown physician leads national resveratrol study for Alzheimers disease
4. Study finds Massachusetts health reform leads to increased inpatient surgical procedures
5. Rutgers leads effort to replicate care management programs in 4 U.S. cities
6. Fun in the Kitchen and Eating 300 Calorie Meals Leads to Weight Loss for Fat Guy
7. AIUM and AUA guideline development leads to practice accreditation for urologic ultrasound
8. A Void In The Independent Pharmacy Industry Leads to Independent Rx Consulting, Powered by OurHelix
9. Protein build-up leads to neurons misfiring
10. Expanding Medicaid to low-income adults leads to improved health, fewer deaths
11. Stress during pregnancy leads to abdominal obesity in mice offspring
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at Children’s National ... 49th Congress of the International Society of Paediatric Oncology (SIOP) Oct. 12-15. ... for Cancer and Blood Disorders at Children’s National, and Stephen P. Hunger, M.D., ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned and Grand ... Best and Brightest in Wellness® by Best and Brightest. OnSite Wellness will be ... Oct. 20 from 7:30 a.m. to 2 p.m. at the Henry Autograph Collection ...
(Date:10/12/2017)... BALTIMORE (PRWEB) , ... October 12, 2017 , ... ... average of $3,296 in property taxes a year. In some states—like New York, ... higher. , By contrast, many overseas retirement havens have extremely low property-tax rates, ...
(Date:10/12/2017)... D.C. (PRWEB) , ... October 12, 2017 , ... ... Cal Dining at the University of California Berkeley, and other leading institutions in ... the buying power of institutions to change the way animals are raised for ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... manufacturer, has expanded its executive staff with the addition of industry sales leader, ... role, Slott will develop the national distribution and sales network, direct the efforts ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... , Sept. 25, 2017  EpiVax, Inc., ... vaccine design, and immune-engineering today announced the launch ... the development of personalized therapeutic cancer vaccines. EpiVax ... provided exclusive access to enabling technologies to the ... MBA will lead EpiVax Oncology as Chief Executive ...
(Date:9/19/2017)... -- HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy ... team developments today:   ... ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has led R&D ...
(Date:9/13/2017)... Sept. 13, 2017   OrthoAtlanta has been named ... Football Host Committee (AFHC) for the 2018 College Football Playoff ... 2018, at Mercedes-Benz Stadium in Atlanta, Georgia ... AFHC "I,m In" campaign, participating in many activities leading up ... ...
Breaking Medicine Technology: