Navigation Links
HIV plus HPV leads to increased anal cancer risk in men
Date:12/3/2013

Human papillomavirus, or HPV, which can cause cervical cancer in women, is also known to cause anal cancer in both women and men. Now, a study led by researchers at the UCLA School of Nursing has found that older HIV-positive men who have sex with men are at higher risk of becoming infected with the HPVs that most often cause anal cancer.

The researchers also report that smoking increases the risk of infection with specific types of HPV among both HIV-infected and uninfected older men by up to 20 percent. This is the first large U.S. study of a group of HIV-infected and uninfected men between the ages of 40 and 69 who have sex with men. Study participants were examined twice a year for up to 25 years.

"Invasive anal cancer is a health crisis for gay, bisexual and other men who have sex with men," said Dorothy J. Wiley, associate professor at the UCLA School of Nursing and lead author of the study, which was published Nov. 20 in the journal PLOS ONE. "Right now, invasive anal cancer rates among HIV-infected men who have sex with men surpass rates for seven of the top 10 cancers in men."

The study, which involved more than 1,200 participants, was performed at four sites in the United States. Nearly 49 percent of the men were HIV-positive. During semi-annual visits, all the men were examined for demographic, sexual, behavioral and HIV-infection characteristics and were tested for HPV.

The researchers found that HPV infections were common among all the men in the study and that the proportion of men affected by HPV remained consistently high across the 40󈞱 age range. However, HIV-infected men between the ages of 40 and 69 showed a higher risk for HPV infection than HIV-uninfected men.

The study also found that for HIV-positive men, taking antiretroviral therapies as prescribed appeared to lower their risk for the HPV infections that cause cancers. Avoiding tobacco use also lowered the risk of HPV infections among all the men.

"This study highlights the benefit of adhering to HIV treatment, which among HIV-infected men who have sex with men, is important for cancer-prevention strategies," Wiley said.

The next step in this research is to begin looking at ways to develop better, more effective HPV infectionprevention strategies, including vaccination for age-eligible males and screening and treatment programs for high-risk men who have sex with men to prevent invasive cancers.

"Right now, we perform colonoscopies to prevent colon cancer, where 53 men per 100,000 are diagnosed annually," Wiley said. "Unfortunately, we do not provide screening tests routinely for anal cancer for men who have sex with en, where the numbers are much higher 78 men per 100,000."


'/>"/>

Contact: Laura Perry
lperry@sonnet.ucla.edu
310-794-4022
University of California - Los Angeles
Source:Eurekalert

Related medicine news :

1. Epilepsy Leads to More Brain Abnormalities Over Time
2. How a cancer drug leads to diabetes
3. Georgetown physician leads national resveratrol study for Alzheimers disease
4. Study finds Massachusetts health reform leads to increased inpatient surgical procedures
5. Rutgers leads effort to replicate care management programs in 4 U.S. cities
6. Fun in the Kitchen and Eating 300 Calorie Meals Leads to Weight Loss for Fat Guy
7. AIUM and AUA guideline development leads to practice accreditation for urologic ultrasound
8. A Void In The Independent Pharmacy Industry Leads to Independent Rx Consulting, Powered by OurHelix
9. Protein build-up leads to neurons misfiring
10. Expanding Medicaid to low-income adults leads to improved health, fewer deaths
11. Stress during pregnancy leads to abdominal obesity in mice offspring
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... for human induced pluripotent stem (iPS) cells and other difficult to transfect cells, ... Cloning Medium. The PluriQ™ G9™ Gene Editing System is a complete ...
(Date:6/24/2016)... ... June 24, 2016 , ... Finally, a bruise cream ... procedures, dermaka cream can be incorporated into the post-surgical treatment plans of a variety ... , dermaka cream is very effective for bruising and causes a rapid resolution ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Randall Markarian, DDS, are co-chairs for the Illinois State Dental Society (ISDS) Foundation’s ... 15-16 at the Gateway Convention Center in Collinsville. , They expect ...
(Date:6/24/2016)... ... June 24, 2016 , ... SpiritQuest Sedona Retreats, located in ... Sedona, surrounded by famous vortex sites: Cathedral Rock, Airport Mesa, and Boynton Canyon. The ... the Lodge at Sedona as well as the Sedona Rouge, both popular accommodations for ...
(Date:6/23/2016)... ... June 23, 2016 , ... Terumo BCT, a global ... for clinical transfusion research programs and for the blood supply in the Netherlands, ... Predictive Analytical Rating Score (PREPAReS) study. , Currently in its sixth year, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... The vast majority of dialysis patients currently ... are usually 3 times a week, with treatment times ... time, equipment preparation and wait time.  This regimen can ... patients who are elderly and frail.  Many elderly dialysis ... centers for some duration of time. Residents ...
(Date:6/23/2016)... NEW YORK , June 23, 2016 ... rough waters, but it continues to present great opportunities ... featured companies for today: Intrexon Corp. (NYSE: ... ), Arena Pharmaceuticals Inc. (NASDAQ: ARNA ), ... Learn more about these stocks and receive your complimentary ...
(Date:6/23/2016)... -- Delcath Systems, Inc. (NASDAQ: DCTH ), a ... of primary and metastatic liver cancers, announces that the ... www.againsttheodds.eu - has been awarded a silver medal ... The website was developed as an education ... who are coping with the devastating diagnosis of cancer ...
Breaking Medicine Technology: