Navigation Links
HIV drugs, Abacavir and Didanosine increase the risk of heart attack
Date:2/7/2008

A study to assess the adverse effects of anti-retroviral drugs shows that two widely-used HIV drugs are associated with an increased risk of heart attack/the formation of blood clots in the heart. With the use of Didanosine, the risk of developing a heart attack increases by 49%, with Abacavir; the increased risk is 90%. The effect is most pronounced in patients with a high underlying cardiovascular risk. The research findings also show that the adverse effect is reversible, if patients discontinue use of these particular drugs.

The scientists who conducted the study recommend that patients on Abacavir or Didanosine should evaluate their underlying cardiovascular risk with their doctor and discuss whether any changes to their drug regime are warranted. The scientists strongly urge HIV patients not to stop taking Abacavir or Didanosine, before they have consulted their doctor.

Since the study began in 1999, D:A:D (the Data Collection of Adverse effects of Anti-HIV Drugs Study) has examined the side-effects of anti-retroviral drugs, including a possible increase in the risk of heart attack. Recent analysis has focused on a class of drugs, not previously examined, known as the nucleoside analogues, which inhibit the HIV virus by preventing it from multiplying. This class of drugs includes Stavudine, Zidovudine, Lamivudine, Abacavir and Didanosine. Only the last two drugs in the analysis were shown to have an adverse effect with respect to heart disease.

The side-effects associated with Didanosine and Abacavir are, naturally, most significant for HIV-infected patients who already have a high underlying cardiovascular risk. The drug effect increases an individual persons underlying risk by a factor of 1.9 for a person on Abacavir, and 1.49 for a person on Didanosine. For a person with a low underlying risk, this increase in risk is still negligible, but for someone with a high underlying risk, this could have serious co
'/>"/>

Contact: Communication Department
email@sund.ku.dk
453-532-7069
University of Copenhagen
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Targeting gut bugs could revolutionize future drugs, say researcher
2. MicroRNAs may be key to HIVs ability to hide, evade drugs, Jefferson scientists find
3. American Pacific Reports Revenue Increase of 34% and Net Income of $2.9 Million for Fiscal 2008 First Quarter
4. Medical Cost Increases to Accelerate Worldwide Over Next Five Years, Watson Wyatt Poll Finds
5. Otter Tail Corporation Reports Record Revenues and Net Income From Continuing Operations for 2007; Earnings Per Share of $1.78; Board Approves Dividend Increase
6. UKs largest charity announces increase in funding to almost £4 billion over 5 years
7. CRH Medical Corporation announces substantial increase in patient visits
8. Will This President Never Learn? Another Budget -- Another Increase to Ineffective Abstinence-Only Programs
9. FY2009 Budget Increases International Development Funding but Does Little for Domestic Nutrition Programs
10. ATS Medical Expects Fourth Quarter Revenue to Increase by Approximately 32%
11. Natural Nutrition Operating Subsidiary Reports Record 29% Increase in Revenues for 2007 of $17,460,000
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... Representatives with Recharge Retreats ... list of destinations for International Yoga Teacher Trainings. , ... that the company chose Italy due to the fact ... trainings since it's an easy flight for Canadians and ... from all over Europe, UK, Africa, and the Middle ...
(Date:8/27/2014)... The Global and China Maleic Anhydride Industry ... state of the Maleic Anhydride industry in Global and ... the industry, including definitions, applications and industry chain structure. ... provided with a focus on history, developments, trends and ... international and Chinese situation is also offered. Get a ...
(Date:8/27/2014)... IQ Formulations , a leading manufacturer of ... of the Cystic Fibrosis Foundation. For an entire month ... led by TigerFitness.com in which 5 percent of the ... to the respected nonprofit organization. , Last year, ... Isla, a young girl fighting Cystic Fibrosis. The company ...
(Date:8/27/2014)... 27, 2014 Aspirus Wausau Hospital today ... US with Buzz™ Digital O.R. at Aspirus Wausau Hospital, ... 13 new operating rooms will be Buzz, a centralized ... integrative system supports planning, navigation, imaging and communications connectivity. ... of intuitive software and hardware all controlled from the ...
(Date:8/27/2014)... Salt Lake City, Utah (PRWEB) August 27, 2014 ... sponsorship of Wasatch Indoor Bike Park, Utah’s first indoor mountain ... an assortment of mountain and park-style bikes in both adult ... , SCOTT Sports, who already operated a distribution warehouse in ... Idaho, to Salt Lake City. , “We are proud to ...
Breaking Medicine News(10 mins):Health News:Recharge Retreats Adds Italy to Its International Yoga Teacher Trainings Destinations 2Health News:Recharge Retreats Adds Italy to Its International Yoga Teacher Trainings Destinations 3Health News:Maleic Anhydride Industry & Isoprene Market Global and China Analysis Now Available at ReportsnReports.com 2Health News:Maleic Anhydride Industry & Isoprene Market Global and China Analysis Now Available at ReportsnReports.com 3Health News:Maleic Anhydride Industry & Isoprene Market Global and China Analysis Now Available at ReportsnReports.com 4Health News:Maleic Anhydride Industry & Isoprene Market Global and China Analysis Now Available at ReportsnReports.com 5Health News:IQ Formulations Contributes Sizeable Donation to Cystic Fibrosis Foundation 2Health News:Aspirus Wausau Hospital Announces First Large Scale Digital Operating Room Integration Project in the US 2Health News:Aspirus Wausau Hospital Announces First Large Scale Digital Operating Room Integration Project in the US 3Health News:SCOTT Sports to Sponsor Wasatch Indoor Bike Park 2
... Inc. (OTC Bulletin Board: NZYM) today announced financial results for its ... , , For the fourth quarter ended March ... of $4.6 million for the same period last year. Gross ... income of $1.1 million for the same period last year. ...
... Health Care, Insurers Can "Discriminate...On the Basis of Which ... June 3 At a press conference today in ... Poizner to praise new rules proposed by the Department ... when they get sick. The group called on ...
... ... communication breakdowns that contribute to delays in care and clinical decision-making, Fauquier Hospital in ... 15-25 minutes per shift. , ... Knoxville, TN (PRWEB) June 3, 2009 -- In an effort to eliminate ...
... Informatics Solution enables healthcare professionals to more immediately ... information , , WARRENDALE, Pa., June 3 ... an informatics application that enables healthcare professionals to ... radiology patients, contrast injections from nearly anywhere. This ...
... USAID/State Department/Private Sector Initiative Unveils Initial Aid to ... and CAFAmerica,s Saxon-Harrold Report on Progress. , ... Woman Initiative ( http://www.OneWomanInitiative.org ), a one-year-old public/private ... Muslim populations, today announced its first grants, totaling ...
... release is available in French . , ... discovered that a widely used anti-diabetic drug can boost the ... treatments. Their findings will be published June 3 in the ... Dr. Russell Jones, an assistant professor at McGill,s Goodman Cancer ...
Cached Medicine News:Health News:Synthetech Announces Fiscal 2009 Results 2Health News:Synthetech Announces Fiscal 2009 Results 3Health News:Synthetech Announces Fiscal 2009 Results 4Health News:Synthetech Announces Fiscal 2009 Results 5Health News:Synthetech Announces Fiscal 2009 Results 6Health News:Consumer Watchdog Praises Insurance Commissioner Poizner for Health Insurance 'Rescission' Rules, Pans Schwarzenegger Administration for Failure to Regulate HMOs 2Health News:Consumer Watchdog Praises Insurance Commissioner Poizner for Health Insurance 'Rescission' Rules, Pans Schwarzenegger Administration for Failure to Regulate HMOs 3Health News:Fauquier Hospital Nurses Increasing Productivity by 15-25 Minutes per Shift with PerfectServe 2Health News:MEDRAD Introduces Manage.Report - Advances Evidence-Based Decision Making 2Health News:MEDRAD Introduces Manage.Report - Advances Evidence-Based Decision Making 3Health News:'One Woman Initiative' Announces First Grants to Women's Organizations in Five Nations 2Health News:'One Woman Initiative' Announces First Grants to Women's Organizations in Five Nations 3Health News:'One Woman Initiative' Announces First Grants to Women's Organizations in Five Nations 4Health News:Common diabetes drug may 'revolutionize' cancer therapies 2
(Date:8/27/2014)... , Aug. 27, 2014 Amgen (NASDAQ: ... Drug Administration (FDA) has granted priority review designation for ... Ivabradine is an oral drug that inhibits the ... sinoatrial node, the body,s cardiac pacemaker. 1 Ivabradine ... on myocardial contractility or ventricular repolarization. 1 Heart ...
(Date:8/27/2014)... -- "Fatty Liver Disease Global Clinical Trials Review, H2, ... trial scenario. This report provides elemental information and data ... Disease . It includes an overview of the trial ... of trial conduction across the globe. The databook offers ... phase, trial status, prominence of the sponsors and also ...
(Date:8/27/2014)... 2014 IRIDEX Corporation (NASDAQ: IRIX ) ... is scheduled to make an investor presentation at the ... Eastern Time on Wednesday, September 3, in New York City.  ... presentation will be available in the Investors section of the ... IRIDEX IRIDEX Corporation was founded in 1989 and ...
Breaking Medicine Technology:FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 2FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 3FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 4FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 5FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 6FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 7Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 2Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 3Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 4Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 5
... New Jersey, April 16, 2012 NoviPet , ... , will showcase new food supplements for dogs at the Backer,s ... take place on April 18-20 2012, in Atlantic City, New Jersey. ... company,s booth 834 at Atlantic City Convention Center. NoviPet intends to ...
... MUMBAI, India, April 15, 2012  Piramal Imaging SA ("Piramal"), ... PIRHEALTH, BSE: 500302], announced positive first results from a ... florbetaben reliably detects beta-Amyloid in the brain during life ... potential tool to aid in the diagnosis and assessment ...
Cached Medicine Technology:NoviPet to Present New Food Supplements for Dogs at Pet Industry Spring Trade Show 2Encouraging Phase III Study Results Show PET Imaging with Florbetaben Reliably Detects Beta-Amyloid in the Brain 2Encouraging Phase III Study Results Show PET Imaging with Florbetaben Reliably Detects Beta-Amyloid in the Brain 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: