Navigation Links
HIV drug that protects a fetus should be avoided for one year after childbirth, researchers say
Date:2/25/2010

BIRMINGHAM, Ala. Women given the human immunodeficiency virus (HIV) prevention drug nevirapine to protect their fetus should not use an HIV-drug regimen that contains nevirapine for at least one year after childbirth, say researchers at the University of Alabama at Birmingham (UAB).

A new UAB study found that while nevirapine works well to prevent mother-to-child HIV transmission, a single dose of nevirapine in infected pregnant women can trigger resistance to some forms of the AIDS-drug cocktail known as combination antiretroviral treatment (ART). This nevirapine-induced resistance fades after about 12 months and no longer hinders ART, says UAB Professor of Obstetrics and Gynecology Jeffrey S.A. Stringer, M.D., the study's lead author.

The findings are published in PLoS Medicine, a journal of the nonprofit Public Library of Science.

Single-dose nevirapine is widely used to prevent mother-to-child transmission of HIV, an infection that affects more than 30 million people globally and leads to more than 2 million AIDS-related deaths each year.

"This study shows that women who need treatment more than 12 months after using nevirapine to prevent mother-to-child transmission safely can use standard first-line treatments in their countries," says Stringer, director of the UAB-affiliated Center for Infectious Disease Research in Zambia. "Women who need treatment sooner than that should use a combination that does not contain nevirapine, typically an ART regimen that contains protease-inhibitor drugs."

The UAB study included 878 infected women in Zambia, Cote d'Ivoire and Thailand. Some were given single-dose nevirapine and others were not; all participants were given ART immediately upon confirmed infection and monitored for one year.

Nevirapine continues to be the backbone of anti-HIV therapy in the developing world, and its usefulness in preventing mother-to-child transmission is confirmed in the new stu
'/>"/>

Contact: Troy Goodman
tdgoodman@uab.edu
205-934-8938
University of Alabama at Birmingham
Source:Eurekalert

Page: 1 2

Related medicine news :

1. What gives us sunburn protects crayfish against bacteria
2. Broccoli sprout-derived extract protects against ultraviolet radiation
3. Early HRT Protects a Womans Heart
4. Regular Walking Protects the Aging Brain
5. Ovary Removal Protects Some High-Risk Women
6. Cell recycling protects tumor cells from anti-cancer therapy
7. Fasting Before Chemo Protects Healthy Cells
8. Injectable Antibiotic Protects Against Lyme Disease in Mice
9. New Drug Protects Against Radiation Damage
10. Gene Variant Protects Black Heart Failure Patients
11. Treating Stomach Infection Early Protects Against Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... ... ... Enterprises, LLC has announced the opening of its newest store location in Zanesville, Ohio. The ... The premium frozen yogurt chain was listed as #22 on the Inc. 500 list of ... Zanesville, OH 43701. , “We are thrilled to finally open a store in Zanesville ...
(Date:7/7/2015)... ... ... a reputable source of authentic tickets for the CONCACAF Gold Cup Group A ... Foxborough, Massachusetts. , The second round of matches being held from Group A of the ... will be held on Friday, July 10th and will feature Honduras vs. Panama and the ...
(Date:7/7/2015)... ... July 07, 2015 , ... An article published June ... how innovation and technology would be the “key factors” in the growth of ... accessibility and affordability, especially in emerging and growing markets. According to the compounding ...
(Date:7/7/2015)... ... 07, 2015 , ... Researchers at UC Davis have reviewed ... didn’t) and how similar programs can be improved. , Interviewing staff, clinicians and ... of Practice (HEALTH COP) program, the team identified four factors that helped clinicians ...
(Date:7/7/2015)... Washington (PRWEB) , ... July 07, 2015 , ... ... that will provide payment parity for an expanded list of telehealth services available ... bi-partisan sponsorship from Representatives Gregg Harper (R-MS 3), Diane Black (R-TN 6) and ...
Breaking Medicine News(10 mins):Health News:sweetFrog Grows in Ohio with New Store Opening 2Health News:CONCACAF Group A Tickets: USA vs. Haiti & Honduras vs. Panama at Gillette Stadium: Ticket Down Slashes CONCACAF Gold Cup Group A Tickets in Foxborough 2Health News:Recent Article on Pharmaceutical Innovation Highlights the Need for Creative Solutions to Common Problems, Says Medlife Pharmacy 2Health News:Recent Article on Pharmaceutical Innovation Highlights the Need for Creative Solutions to Common Problems, Says Medlife Pharmacy 3Health News:UC Davis Study Identifies Tools, Strategies for Enhancing Obesity Prevention in Rural Communities 2Health News:UC Davis Study Identifies Tools, Strategies for Enhancing Obesity Prevention in Rural Communities 3Health News:The American Telemedicine Association Supports Legislation to Expand Medicare Coverage for Telemedicine Services 2
... health research? The National Institutes of Health (NIH) wants ... meeting March 4-6 on behalf of the NIH Office ... develop research priorities for the next decade. The meeting ... scientists, health-care providers, patients, community groups, advocacy groups and ...
... the University of California, San Diego, Stanford University School of ... a chronic form of leukemia can progress into a deadlier ... an indicator of when this type of cancer chronic ... more accurate prognoses for the disease and improved treatment choices. ...
... BMP Sunstone,Corporation (Nasdaq: BJGP ) (,BMP ... 8, 2009, senior executives of Sunstone (Tangshan),Pharmaceutical Co., ... Vice Premier of,the State Counsel of the PRC, ... and other senior central and local government officials. ...
... Medical Interpreters Association (IMIA) appointed a representative for ... The IMIA is proud to announce Lola Bendana, ... for Canada. Her role is primarily to represent ... and initiate activities that will promote the medical ...
... Nektar Therapeutics (Nasdaq: NKTR ) announced today ... Phase 1 dose-escalation study of NKTR-105, a novel PEGylated ... assess the safety, pharmacokinetics and anti-tumor activity of NKTR-105 ... have failed all prior available therapies. "The start ...
... GlaxoSmithKline today announced initiation and dosing of the ... programme to evaluate the efficacy, safety and tolerability ... Syncria(R) (albiglutide) in men and women with type ... include more than 4,000 patients."Despite continued advances in ...
Cached Medicine News:Health News:WU hosts public hearing, conference to help NIH prioritize women's health research 2Health News:Scientists uncover indicator that warns leukemia is progressing to more dangerous form 2Health News:Scientists uncover indicator that warns leukemia is progressing to more dangerous form 3Health News:BMP Sunstone Reiterates Commitment to Quality, Innovation and Long-Term Growth at Meeting with Senior Officials 2Health News:BMP Sunstone Reiterates Commitment to Quality, Innovation and Long-Term Growth at Meeting with Senior Officials 3Health News:IMIA Interpreter Association Appoints Canada Representative 2Health News:IMIA Interpreter Association Appoints Canada Representative 3Health News:Dosing Begins in Phase 1 Clinical Study Evaluating NKTR-105 in Cancer Patients With Refractory Solid Tumors 2Health News:Dosing Begins in Phase 1 Clinical Study Evaluating NKTR-105 in Cancer Patients With Refractory Solid Tumors 3Health News:Dosing Begins in Phase 1 Clinical Study Evaluating NKTR-105 in Cancer Patients With Refractory Solid Tumors 4Health News:GSK Initiates Phase III Programme for Novel Type 2 Diabetes Medication, Syncria(R) (albiglutide) 2Health News:GSK Initiates Phase III Programme for Novel Type 2 Diabetes Medication, Syncria(R) (albiglutide) 3
(Date:7/7/2015)... July 7, 2015 BioRx, a Diplomat company (NYSE: ... a Top Workplace in 2015 based on a survey held ... Media Group and a Philadelphia -based research ... and was completed by employees across the Greater ... area, with topics ranging from workplace environment to overall organizational ...
(Date:7/7/2015)... 7, 2015 Hill-Rom,s recent announcement that ... in cash and stock means the company can ... to Kalorama Information. The healthcare market researcher said ... device and advanced wound care markets, and is ... lifting devices, and other healthcare equipment. Welch Allyn,s ...
(Date:7/7/2015)... --  ICD-10 Charts ( www.icd10charts.com ) announced today ... officially launched its newest line of ICD-10 preparation ... new 4 Step ICD-10 Implementation Plan.  Both of ... Charts resources and mobile apps, are available to ... the release of these resources, the company has ...
Breaking Medicine Technology:BioRx Named a Top Workplace in 2015 by Enquirer Media 2BioRx Named a Top Workplace in 2015 by Enquirer Media 3Kalorama: Hill-Rom Enters Monitoring Market with Welch Allyn Purchase 2Kalorama: Hill-Rom Enters Monitoring Market with Welch Allyn Purchase 3ICD-10 Charts Releases Revolutionary Free Solution for Complete ICD-10 Preparation 2ICD-10 Charts Releases Revolutionary Free Solution for Complete ICD-10 Preparation 3ICD-10 Charts Releases Revolutionary Free Solution for Complete ICD-10 Preparation 4
... WIRE)--May 15, 2007 - Synthetic Blood,International, Inc. ... analysis of its Phase IIa study with ... line with preliminary,study results announced in December ... of increasing patients' oxygen,tension levels compared with ...
... WIRE)--May 17, 2007 - Salix,Pharmaceuticals, Ltd. (NASDAQ:SLXP) today ... the Company's products,will be presented at Digestive Disease ... Digestive Disease Week is considered the,largest and most ... Every year it attracts more than 16,000 physicians,researchers ...
Cached Medicine Technology:Positive Statistical Analysis from Synthetic Blood's Oxycyte,Traumatic Brain Injury Trial Indicates Achievement of Primary,Endpoint 2Positive Statistical Analysis from Synthetic Blood's Oxycyte,Traumatic Brain Injury Trial Indicates Achievement of Primary,Endpoint 3Salix Pharmaceuticals Previews Digestive Disease Week 2007 2Salix Pharmaceuticals Previews Digestive Disease Week 2007 3Salix Pharmaceuticals Previews Digestive Disease Week 2007 4Salix Pharmaceuticals Previews Digestive Disease Week 2007 5
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: