HIV conquers immune system faster than previousl... ( DURHAM N.C. New research into the e...)

HIV conquers immune system faster than previously realized

Date:7/18/2008

DURHAM, N.C. New research into the earliest events occurring immediately upon infection with HIV-I shows that the virus deals a stunning blow to the immune system earlier than was previously understood. According to scientists at Duke University Medical Center, this suggests the window of opportunity for successful intervention may be only a matter of days not weeks after transmission, as researchers had previously believed.

Appearing in the August issue of the Journal of Virology, the finding may make the challenge of designing an effective HIV/AIDS vaccine appear daunting. But researchers say the study has also yielded a blueprint for what a successful vaccine should look like, and moreover, when such a vaccine would need to work.

Until now, scientists believed that the window of opportunity to intervene in the process of HIV-1 infection lay in the three to four weeks between transmission and the development of an established pool of infected CD4 T cells. HIV-1 cripples the immune system by invading and killing CD4 T cells, key infection-fighters in the body.

"But this new study shows that HIV-I does a lot of damage to the immune system very early in that time frame, and now we feel that the opportunity to intervene most effectively may range from about five to seven days after infection," said Barton Haynes, M.D., the senior author of the study and director of the Center for HIV/AIDS Vaccine Immunology (CHAVI) at Duke University Medical Center.

Haynes said the findings suggest that an optimal vaccine strategy would have to pack a double punch: First, establishing as much immunity as possible before infection, much as classic vaccines do, and then following a few days later with a mechanism to provoke a strong, secondary, broad-based antibody response. "Vaccine candidates to date have pretty much followed a single strategy. Now we know that we need to activate multiple arms of the immune system and we have a be
'/>"/>

Contact: Michelle Gailiun
michelle.gailiun@duke.edu
919-660-1306
Duke University Medical Center
Source:Eurekalert

0

GOOD

Page: 1 2 3
Related medicine news :

1. Peptimmune Announces the Second Close of Series D Private Financing
2. Brain Cancer Vaccines Immune Response Key to Outcomes
3. Brain cancer study: Magnitude of post-vaccine immune response linked to clinical outcomes
4. Researchers link Huntingtons disease to overactive immune response in the brain
5. Breakthrough "Neuro Nutrition" Targets the Brain and Vagus Nerve To Boost the Body's Immune, Hormone and Neurological Systems
6. Multi-target immune therapy improves outcomes of severe lupus nephritis
7. Immune Molecule Key to Preventing Organ Rejection
8. Nasal spray using bodys immune system provides hope of cure for common cold
9. Immune Design Announces $18 Million Series A Financing
10. Autoimmune Disease Treatment May Not Dampen Immune System
11. Immune molecule that plays a powerful role in avoiding organ rejection identified

Post Your Comments:

(Date:5/20/2013)... 20, 2013 Dr. Robert Mokbel is ... trained to use the Laser Assisted New Attachment Procedure, ... patients with gum disease. LANAP may help many Fountain ... gum disease restore the jawbone support necessary to support ... of plaque and tartar in the mouth. Daily oral ...

(Date:5/20/2013)... May 20, 2013 In order to prepare ... and wellness team from DrSmartphoneMD launched an article series to ... , The series launched with the precautions that ... of the DrSmartphoneMD program are not one of the 3.5 ... that more than 90% of all skin cancer cases are ...

(Date:5/20/2013)... (PRWEB) May 20, 2013 Daily Gossip, online ... provide its readers with useful tips that can help them ... , According to the website Natural Vitiligo Treatment System ... the numerous positive reviews it has received from the persons ... until now, but Daily Gossip has interviewed some of the ...

(Date:5/20/2013)... 20, 2013 Eben Pagan's ... the public creating a frenzy among business owners ... elite business training. WealthSpringMarketing.com's Tiffany Hendricks has published ... an exclusive bonus. , "Eben Pagan is a ... training to individuals serious about success," reports Hendricks. ...

(Date:5/20/2013)... May 20, 2013 Mombo from ... national conference of the US Lactation Consultant Association (USLCA) ... including nurses, doctors and other health professionals. , ... at helping lactation professionals discover and learn about the ... of the most popular nursing pillows, which new mothers ...

Breaking Medicine News(10 mins):Health News:Fountain Valley, Ca Gum Disease Patients with Missing Teeth Can Now Receive Laser Gum Surgery from Dr. Robert Mokbel for Success with Dental Implants 2 Health News:Combat Skin Cancer In Summer Months 2 Health News:New Natural Vitiligo Treatment System That Helps People Treat Vitiligo Permanently Revealed by Daily Gossip Magazine 2 Health News:Eben Pagan's Accelerate: Review and Bonus Released By WealthSpringMarketing.com 2 Health News:Comfort & Harmony™ Exhibited mombo™ Nursing Pillow at USLCA’s First Inaugural Conference 2

[0] Fountain Valley, Ca Gum Disease Patients with Missing Teeth Can Now Receive Laser Gum Surgery from Dr. Robert Mokbel for Success with Dental Implants [0] Combat Skin Cancer In Summer Months [0] New Natural Vitiligo Treatment System That Helps People Treat Vitiligo Permanently Revealed by Daily Gossip Magazine [0] Eben Pagan's Accelerate: Review and Bonus Released By WealthSpringMarketing.com [0] Comfort & Harmony™ Exhibited mombo™ Nursing Pillow at USLCA’s First Inaugural Conference

... and ... IVUS, SAN DIEGO, Nov. 8 Volcano Corporation,(Nasdaq: ... measurement (FM) products designed to enhance the diagnosis and,treatment of ... quarter and first nine months of fiscal 2007. For ...

... Nabi ... Biologics to Biotest, BOCA RATON, Fla., ... third quarter,financial results. The company recorded a net loss of $15.9 ... which included,$7.5 million, or $0.12 per share, of expenses for unusual ...

... to Aid ... Decision-Making, MILFORD, Mass., ... Synapt(TM) HDMS,System to hasten its drug discovery efforts in the area ... C, HIV, osteoporosis, osteoarthritis, and high blood pressure.,Installed in June, the ...

... Hispanic youth report better dental health habits than their non-Hispanic ... researchers at Columbia University Mailman School of Public Health. ... the Journal of Health Care for the Poor and Underserved, ... community in America. , The study, a snapshot of more ...

... stomach-shielding drugs, patient health has suffered, researchers say , , ... Vioxx and Bextra off the market to spare patients, ... new study suggests. , Rates of gastrointestinal events serious ... cox-2 inhibitor medications were ordered off the market in ...

... have identified a way to detect neural progenitor cells ... system cells, in the living human brain using a ... The finding, supported by the National Institutes of Health ... depression, Parkinson,s disease, brain tumors, and a host of ...

Volcano Reports Record Third Quarter Revenues Nabi Biopharmaceuticals Announces Third Quarter 2007 Financial Results and Positive Vote from November 8, 2007 Special Stockholders Meeting Medivir Reshapes Drug Discovery Study of minority New York City youth finds unequal burden of poor dental health Vioxx Ban Tied to Rise in Serious GI Trouble Imaging neural progenitor cells in the living human brain

(Date:5/20/2013)... SAN DIEGO , May 20, 2013 Volcano ... and manufacturer of precision guided therapy tools designed to ... vascular disease, today announced it will highlight its efforts ... including its Fractional Flow Reserve (FFR) and iFR ® ... clinical and educational presentations and events at EuroPCR 2013 ...

(Date:5/20/2013)... Pa. , May 20, 2013 B. ... patient, clinician and environmental safety with products, services ... B.Braun will feature its innovative Outlook® 400ES and ... and barcoding capabilities at the American Association of ... at the Boston Convention ...

(Date:5/20/2013)... May 20, 2013 Landauer, Inc. (NYSE: ... environmental radiation measurement and monitoring, outsourced medical physics services ... its Board of Directors declared, at its meeting on ... $0.55 per share for the third quarter of fiscal ... 2013, to shareholders of record on June 7, 2013. ...

Breaking Medicine Technology:Volcano to Highlight its Physiology Expansion Efforts at EuroPCR 2013 2 Volcano to Highlight its Physiology Expansion Efforts at EuroPCR 2013 3 Volcano to Highlight its Physiology Expansion Efforts at EuroPCR 2013 4 B. Braun Committed To Improving Patient Safety 2 Landauer, Inc. Declares Regular Cash Dividend 2

[0] Volcano to Highlight its Physiology Expansion Efforts at EuroPCR 2013 [0] B. Braun Committed To Improving Patient Safety [0] Landauer, Inc. Declares Regular Cash Dividend

... Conn., Sept. 16 MedClean Technologies (OTC Bulletin Board: ... technology for the treatment and disposal of medical waste ... today announced it has signed a distribution agreement with ... organization with over 125 years of combined experience in ...

... Quarterly Dividend -- ABBOTT PARK, Ill., Sept. 16 ... ... ... // Results are keyed by longUrl, so we need to grab the first one. for (var r ...

Cached Medicine Technology:MedClean Technologies Signs Distribution Agreement with Trojan Energy Systems 2 MedClean Technologies Signs Distribution Agreement with Trojan Energy Systems 3 Abbott Declares 347th Consecutive Quarterly Dividend 2 Abbott Declares 347th Consecutive Quarterly Dividend 3 Abbott Declares 347th Consecutive Quarterly Dividend 4 Abbott Declares 347th Consecutive Quarterly Dividend 5 Abbott Declares 347th Consecutive Quarterly Dividend 6

MedClean Technologies Signs Distribution Agreement with Trojan Energy Systems Abbott Declares 347th Consecutive Quarterly Dividend

... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...

... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...

Medicine Products:

Adenosine Deaminase, Body Fluid ADAMTS13 Activity & Inhibitor (VWF Cleaving Protease)Acylcarnitine Quantitative Profile, Plasma Acycloguanosine, Urine