Navigation Links
HIV Medication Patch Shows Promise in Early Trial
Date:10/25/2011

By Randy Dotinga
HealthDay Reporter

TUESDAY, Oct. 25 (HealthDay News) -- Preliminary research suggests that a patch could deliver an AIDS drug to patients, but it's too early to know if it could work in animals, let alone humans.

Still, the findings raise the prospect of a simple way to administer AIDS drugs, which patients don't always take as they should. Patches could be worn for seven days, and an author of the new study said it would add only a fraction of a cent to the cost of the drug itself.

"We are encouraged by these results, and we're ready to go to the next stage of developments," said lead researcher Anthony Ham, director of formulations with the pharmaceutical research company ImQuest BioSciences. The study was funded by the U.S. National Institutes of Health.

The researchers successfully used transdermal patches to administer 96 percent of an AIDS drug to simulated skin over a week, Ham said. The AIDS drug, which is under development, is not available to the public.

"These patches require a low cost to manufacture, have a high rate of release and are able to inhibit HIV infection," Ham said. The next step is to test the patches in animals.

Patients with HIV, the virus that causes AIDS, don't need to cope with the complicated regimens of earlier years that required them to take multiple pills at different times throughout the day. Now, about 70 percent of newly treated patients in the United States take a single pill a day, while patients in other parts of the world may take one pill twice a day, said Rowena Johnston, director of research with the Foundation for AIDS Research.

"Still, the important limitation of pills, regardless of how few there are or even how minimal the side effects, is adherence," Johnston noted. Research has shown that many patients, if not most, don't take their pills all the time.

"The huge potential advantage of a patch, depending on how long it secretes the right level of drug, is the ability to maintain the right level of the drug without the fluctuations observed when adherence to pills is less than perfect," Johnston said.

A patch could also be an effective way to provide medication that prevents people from getting HIV in the first place, she said.

Still, "there's a long way to go between what appears to be promising findings now and a patient's skin," she said. While patches have long been used in other kinds of medicine, researchers will still need to launch studies to test their safety and figure out if they work, she said. "The concept is a good one, but I wonder whether there are fundamental difficulties behind nobody else having successfully developed these before."

The study was scheduled to be presented Tuesday at the American Association of Pharmaceutical Scientists annual meeting in Washington, D.C. Research presented at medical meetings has to be viewed as preliminary because it has not gone through the peer review process required by medical journals.

More information

For more about AIDS, try the U.S. National Library of Medicine.

SOURCES: Anthony Ham, Ph.D., director, formulations, ImQuest BioSciences, Frederick, Md.; Rowena Johnston, Ph.D., director, research, Foundation for AIDS Research, New York City; Oct. 25, 2011, presentation, American Association of Pharmaceutical Scientists annual meeting, Washington D.C.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Certain pain medications do not appear to be associated with skin cancer risk
2. Study supports alternative anti-seizure medication following acute brain injury
3. Enovate Announces New Lightweight Medication Cart Series
4. PharmacyChecker.com Begins Blog About Americans' Access to Affordable Medication
5. NACDS RxIMPACT "Hill Day" Features More Advocates Increased Focus on Medication Adherence
6. South Dakota Students with Asthma Can Breathe Easier After New Law Allows Self-Administered Medications
7. RememberItNow! Launches Mobile Medication Reminder and eHealth Service
8. Medica Selects Fairview Pharmacy Services, LLC to Deliver Medication Therapy Management Services to City of Minneapolis Employees
9. New England Journal of Medicine Article Trumpets “Priority” Status of Helping Patients Take Medications Correctly
10. Pollen.com Reports Five U.S. Cities with Highest Pollen Activity -- Total Prescriptions for Allergy Medications 3.7% Higher than Last Year
11. Low vitamin D levels associated with more asthma symptoms and medication use
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
HIV Medication Patch Shows Promise in Early Trial
(Date:5/27/2017)... TX (PRWEB) , ... May 27, 2017 , ... Hate visiting the dentist? You should ... you'll need to take care of your teeth at home. Here are some dental tips ... after meals. Keep a small toothbrush in your work desk or a locker at school ...
(Date:5/27/2017)... ... 2017 , ... Most us are familiar with the sound of occasional popping ... Osteoarthritis Initiative shows that certain people who experience consistent joint popping, grating and ... doctors the opportunity to treat patients before the problem becomes pronounced, potentially hedging off ...
(Date:5/26/2017)... , ... May 26, 2017 , ... ... at Boston CEO 2017 on May 30th and 31st at The Four Seasons ... for leading executives in the life sciences, offering exclusive access to key decision ...
(Date:5/26/2017)... , ... May 26, 2017 , ... ... of the CareFusion NOX-T3 portable sleep monitor with its Somnoware Sleep Device Interface ... browser-based interface for diagnostic device operations. With this platform, initializing devices and importing ...
(Date:5/26/2017)... ... 26, 2017 , ... via seating is proud to partner ... chair specifically designed for clinical areas. Genie Copper Mesh is a crossover chair ... to provide customers with a game changing chair that is affordably priced,” Chas ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... 9, 2017 Zimmer Biomet Holdings, Inc. (NYSE ... today announced it has earned a spot on ... The Company was ranked among 500 U.S. employers as ... Healthcare Equipment and Services. The annual ... anonymous, independent survey of over 30,000 employees across 25 ...
(Date:5/9/2017)... , May 9, 2017  Oramed Pharmaceuticals ... ), a clinical-stage pharmaceutical company focused on the ... that the Canadian Intellectual Property Office has granted ... Oral Administration of Exenatide". The patent covers Oramed,s ... GLP-1 is an incretin hormone that ...
(Date:5/8/2017)... , May 8, 2017 MACRA replaces ... from fee for service reimbursement. Black Book Research crowdsource-surveyed ... 1.       The Market for MIPS Compliance Technology ... of physician practices with 3 or more clinicians seek ... by Q4. "Given the magnitude of the changes, the ...
Breaking Medicine Technology: