Navigation Links
HIV Medication Patch Shows Promise in Early Trial
Date:10/25/2011

By Randy Dotinga
HealthDay Reporter

TUESDAY, Oct. 25 (HealthDay News) -- Preliminary research suggests that a patch could deliver an AIDS drug to patients, but it's too early to know if it could work in animals, let alone humans.

Still, the findings raise the prospect of a simple way to administer AIDS drugs, which patients don't always take as they should. Patches could be worn for seven days, and an author of the new study said it would add only a fraction of a cent to the cost of the drug itself.

"We are encouraged by these results, and we're ready to go to the next stage of developments," said lead researcher Anthony Ham, director of formulations with the pharmaceutical research company ImQuest BioSciences. The study was funded by the U.S. National Institutes of Health.

The researchers successfully used transdermal patches to administer 96 percent of an AIDS drug to simulated skin over a week, Ham said. The AIDS drug, which is under development, is not available to the public.

"These patches require a low cost to manufacture, have a high rate of release and are able to inhibit HIV infection," Ham said. The next step is to test the patches in animals.

Patients with HIV, the virus that causes AIDS, don't need to cope with the complicated regimens of earlier years that required them to take multiple pills at different times throughout the day. Now, about 70 percent of newly treated patients in the United States take a single pill a day, while patients in other parts of the world may take one pill twice a day, said Rowena Johnston, director of research with the Foundation for AIDS Research.

"Still, the important limitation of pills, regardless of how few there are or even how minimal the side effects, is adherence," Johnston noted. Research has shown that many patients, if not most, don't take their pills all the time.

"The huge potential advantage of a patch, depending on how long it secretes the right level of drug, is the ability to maintain the right level of the drug without the fluctuations observed when adherence to pills is less than perfect," Johnston said.

A patch could also be an effective way to provide medication that prevents people from getting HIV in the first place, she said.

Still, "there's a long way to go between what appears to be promising findings now and a patient's skin," she said. While patches have long been used in other kinds of medicine, researchers will still need to launch studies to test their safety and figure out if they work, she said. "The concept is a good one, but I wonder whether there are fundamental difficulties behind nobody else having successfully developed these before."

The study was scheduled to be presented Tuesday at the American Association of Pharmaceutical Scientists annual meeting in Washington, D.C. Research presented at medical meetings has to be viewed as preliminary because it has not gone through the peer review process required by medical journals.

More information

For more about AIDS, try the U.S. National Library of Medicine.

SOURCES: Anthony Ham, Ph.D., director, formulations, ImQuest BioSciences, Frederick, Md.; Rowena Johnston, Ph.D., director, research, Foundation for AIDS Research, New York City; Oct. 25, 2011, presentation, American Association of Pharmaceutical Scientists annual meeting, Washington D.C.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Certain pain medications do not appear to be associated with skin cancer risk
2. Study supports alternative anti-seizure medication following acute brain injury
3. Enovate Announces New Lightweight Medication Cart Series
4. PharmacyChecker.com Begins Blog About Americans' Access to Affordable Medication
5. NACDS RxIMPACT "Hill Day" Features More Advocates Increased Focus on Medication Adherence
6. South Dakota Students with Asthma Can Breathe Easier After New Law Allows Self-Administered Medications
7. RememberItNow! Launches Mobile Medication Reminder and eHealth Service
8. Medica Selects Fairview Pharmacy Services, LLC to Deliver Medication Therapy Management Services to City of Minneapolis Employees
9. New England Journal of Medicine Article Trumpets “Priority” Status of Helping Patients Take Medications Correctly
10. Pollen.com Reports Five U.S. Cities with Highest Pollen Activity -- Total Prescriptions for Allergy Medications 3.7% Higher than Last Year
11. Low vitamin D levels associated with more asthma symptoms and medication use
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
HIV Medication Patch Shows Promise in Early Trial
(Date:12/2/2016)... ... December 02, 2016 , ... Center for Autism and Related ... those affected by autism spectrum disorder (ASD) and other developmental disabilities. The group, which ... give parents and other caregivers the opportunity to share stories and advice, seek help, ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... of two ostomy patients, standing as living proof that attitude and determination can ... diseases and issues that spike around the holidays. This campaign will offer patients ...
(Date:12/2/2016)... ... December 02, 2016 , ... CloudLIMS.com, a class-leading provider of ... Lite. CloudLIMS Lite helps biobanks, clinical, research and testing laboratories keep track of ... new version is a faster and a more efficient product, allowing batch processing ...
(Date:12/2/2016)... ... December 02, 2016 , ... Rijuven Corp launches rejiva ( http://www.rejiva.com ... and night. No other wearable health technology on the market can deliver all that ... poeple more meaningful insights about their health than the usual heart rate and steps ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... needy individuals and families from eight different sites throughout Miami-Dade and Broward counties. ... 1,000 volunteers worked very hard on Thanksgiving morning by putting together individual meals ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... YORK , December 2, 2016 ... Research titled "Global Market Study on Automated Endoscope Reprocessors: Single ... a CAGR of 8.6% Between 2016 and 2024 " the global automated ... and is expected to expand at a CAGR of 7.2% ... valuation of US$ 1,367.6 Mn by 2024. ...
(Date:12/2/2016)... , Dec. 2, 2016 In the ... sources apart from those derived from C. sativa, the ... Universita` di Napoli Federico II , the Universita` ... the first comprehensive, critical, integrated and unified inventory of ... article focuses on the remarkable chemical and structural ...
(Date:12/2/2016)... British Columbia , December 2, 2016 bioLytical ... den INSTI HIV-Selbsttest, bei den Mitgliedern des Apothekenbundes von Kenia eingeführt. ... ... INSTI HIV Self Test! (PRNewsFoto/bioLytical Laboratories) ...      (Photo: http://photos.prnewswire.com/prnh/20161201/444905 ) ...
Breaking Medicine Technology: