Navigation Links
HIV Drug a Double-Edged Sword for Infants
Date:1/18/2009

Nevirapine protects during breast-feeding, but resistant disease can develop in first year, study shows,,,,

SUNDAY, Jan. 18 (HealthDay News) -- The antiretroviral drug nevirapine may help prevent babies of HIV-positive mothers from getting the virus through breast-feeding, but it also greatly increases the odds of developing drug-resistant HIV if they are infected during the first year of life, a new study finds.

Still, the researchers consider the six-week course of the drug the best alternative available.

Given the higher chance of a baby on nevirapine acquiring treatment-resistant HIV, the authors call for the infants to also receive protease inhibitors (PIs), which can combat nevirapine-resistant HIV strains.

"Until other interventions become available, the extended nevirapine regimen remains a reasonable way to prevent infections through breast-feeding," senior investigator Dr. Deborah Persaud, a pediatric HIV expert at John Hopkins Children's Center, said in a news release issued by the school.

The study, published in the Jan. 1 issue of the Public Library of Science One, noted the treatment is best for HIV-positive mothers in developing countries where bottle feeding is not an alternative because of cost, safety or availability.

HIV infection is estimated to occur in one out of 10 breast-fed infants, most of the time happening in the first 14 weeks of life, according to estimates by the World Health Organization (WHO), which recommends breast-feeding for at least six months despite the known risk of HIV transmission.

Two reports published in 2008 found that a six-week treatment of nevirapine cut the risk of HIV infection from breast-feeding nearly in half, while a 14-week regimen cut it by 66 percent.

More information

The U.S. National Institute of Allergy and Infectious Disease has more about HIV infection in women.



-- Kevin McKeever



SOURCE: Johns Hopkins Children's Center, news release, Jan. 5, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Anemia treatment may be a double-edged sword
2. Cellular senescence a double-edged sword
3. Nicotine in breast milk disrupts infants sleep patterns
4. Shaking may cause brain damage and serious long-term effects to infants
5. Maternal depression and controlling behavior associated with increased stress response in infants
6. Repeat steroids to premature infants linked to cerebral palsy
7. Babies raised in bilingual homes learn new words differently than infants learning one language
8. Research shows how genetic mutation causes epilepsy in infants
9. Combination vaccines okay for infants, study shows
10. $4 million nursing grant focuses on at-risk premature infants
11. McNeil Consumer Healthcare is Voluntarily Withdrawing Infants Cough and Cold Products:
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
HIV Drug a Double-Edged Sword for Infants
(Date:3/24/2017)... ... March 24, 2017 , ... ... inspiring stories about real people of God in congregations across the United States. ... a Presbyterian minister ordained in 1964 who has served congregations in seven states ...
(Date:3/23/2017)... ... March 23, 2017 , ... Demonstrating their commitment to ... public health departments have been awarded national accreditation through the Public Health ... the expanding network of communities across the nation whose health departments meet rigorous ...
(Date:3/23/2017)... ... , ... 82% of adults are unaware of the dangers that infectious bacteria play in mouth ... two times a day that dentists recommend. The ramifications of improper oral upkeep go far ... adults missing 164 million hours of work each year due to dental issues. That is ...
(Date:3/23/2017)... ... 23, 2017 , ... Hakim Unique Group (HUG) just closed ... Healthcom Group (CHG). , The HUG investment is a landmark move, expanding ... CHG is a growing, internationally recognized healthcare management, technology, and services organization. It ...
(Date:3/23/2017)... ... ... After raising more than $1.135 million ($1,479,231 AUD) from nearly 20,000 backers ... crowdfunding history, has established a U.S. Headquarters in New York City, FaceCradle USA, LLC, ... excited to be operating on U.S. shores, where most of our initial crowdfunding backers ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... Research and Markets has announced the addition of the ... ... capillary electrophoresis market to grow at a CAGR of 7.06% during ... Market 2017-2021, has been prepared based on an in-depth market analysis ... and its growth prospects over the coming years. The report also ...
(Date:3/23/2017)... Newborns are highly vulnerable to infections ... their young immune systems typically mount weak antibody ... achieving strong vaccine responses in newborn animals, including ... trials — by adding compounds known as adjuvants ... papers, they also describe improved adjuvant formulations that ...
(Date:3/23/2017)... , March 23, 2017 ... from the TACTI-mel trial of IMP321 in combination with ... the first (1mg/kg) cohort experiencing a complete response. Recruitment ... cohort is expected to be fully recruited by Q317. ... the AIPAC breast cancer study are expected mid-year (recruitment ...
Breaking Medicine Technology: