Navigation Links
HIV Can Penetrate a Woman's Healthy Genital Skin
Date:12/16/2008

Study finds virus can reach immune cells in just 4 hours

TUESDAY, Dec. 16 (HealthDay News) -- A new route of male-to-female transmission of HIV -- in which the virus can travel through healthy genital skin to reach immune cells in just four hours -- has been identified by U.S. researchers.

It's long been believed that the normal lining of the vaginal tract was an effective barrier to HIV during sexual intercourse, because the large HIV virus couldn't penetrate the tissue. But the Northwestern University Feinberg School of Medicine researchers found that HIV can penetrate normal, healthy genital tissue to a depth where it can get to immune cells and infect them.

The researchers labeled HIV viruses with photo-activated fluorescent tags and were able to track the viruses as they penetrated the outermost lining of the female genital tract (the squamous epithelium) in female human tissue obtained through hysterectomy and in animal models.

The findings were expected to be presented Dec. 16 at the American Society for Cell Biology annual meeting, in San Francisco.

"This is an unexpected and important result. We have a new understanding of how HIV can invade the female genital tract," principal investigator Thomas Hope, a professor of cell and molecular biology, said in a university news release.

"Until now, science has really had no idea about the details of how sexual transmission of HIV actually works. The mechanism was all very murky," Hope said.

These findings, if confirmed in future studies, could help in the development of new microbicides and vaccines to protect women against HIV.

"We urgently need new prevention strategies or therapeutics to block the entry of HIV through a woman's genital skin," said Hope. While condoms are 100 percent effective in blocking HIV, "people don't always use them for cultural and other reasons."

Women account for 26 percent of all new HIV cases in the United States, according to the U.S. Centers for Disease Control and Prevention. Based on its most recent analysis of 2005 data, the CDC estimated that there were 56,300 new HIV infections that year, and 31 percent were due to high-risk heterosexual contact. More than half of the new cases of HIV infection worldwide are in women.

More information

The U.S. Food and Drug Administration has more about women and HIV.



-- Robert Preidt



Northwestern University, news release, Dec. 16, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Which segments of the gastrointestinal tract does Salmonella enteritidis penetrate?
2. Fibers in Semen Help HIV Penetrate Cells
3. Beth Israel Deaconess Medical Center Maintains Healthy IT Servers With Third Brigade
4. YMCA of the USA Expands Healthy Communities Initiatives With $6.8 Million Grant from the Robert Wood Johnson Foundation
5. Womens Health The Daily Fix Your Guide to Healthy Habits for Good Nutrition
6. Average Americans Without Health Insurance Are Young and Healthy With Above Average Incomes
7. A Healthy New Year's Resolution for Your Eyes
8. Strikeithealthyfamily.com Provides Parents With Sense of Relief
9. Healthy Eating and Good Nutrition Go Hand-in-Hand in Tight Economic Times
10. Healthy Travel Media Launches Second Edition of Patients Beyond Borders Singapore Edition
11. Nets Provide Fans with Healthy In-Game Snack Option
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: